Condensation of DNA in the oocyte nucleus to form the karyosome is abnormal in homozygous egg chambers. In some cases the DNA is more diffuse than normal or it is threadlike and fragmented.
Eggs derived from homozygous females show a "grandchildless knirps-like" phenotype; they lack polar granules and pole cells and show deletions of abdominal segments similar to that seen in kni mutant embryos.
Embryos derived from vasunspecified mutant females lack pole cells, pole plasm and abdominal segments. Eggs are also an abnormal shape.
vasunspecified has karyosome phenotype, non-suppressible by mei-41unspecified
exuunspecified, vasunspecified has embryo phenotype
exuunspecified vasunspecified double mutants produce dicephalic embryos.
