FB2025_01 , released February 20, 2025
Allele: Dmel\wupA13193
Open Close
General Information
Symbol
Dmel\wupA13193
Species
D. melanogaster
Name
FlyBase ID
FBal0036018
Feature type
allele
Associated gene
Dmel\wupA
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(de la Pompa, 1994)
Mutagen
X ray
(de la Pompa, 1994, Ferrus et al., 1990)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Ferrus et al., 1990)
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      cuticle & procephalic segment

      (de la Pompa, 1994)
      Detailed Description
      Statement
      Reference

      All heterozygous females are dead. Embryos have a thin layer of cuticle in the cephalic region.

      (de la Pompa, 1994)

      Flies manifest chronic vibration of their appendages as well as abnormal action potentials.

      (Ferrus et al., 1990)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      wupA13193 has lethal | dominant phenotype, suppressible by Dp(1;3)JC153

      (Casas-Tintó and Ferrús, 2021)

      wupA13193 has lethal | dominant phenotype, suppressible by Dp(1;2)CH322-143G12

      (Casas-Tintó and Ferrús, 2021)
      NOT suppressed by
      Statement
      Reference

      wupA13193 has lethal | dominant phenotype, non-suppressible by Dp(1;2)CH322-61E2

      (Casas-Tintó and Ferrús, 2021)

      wupA13193 has lethal | dominant phenotype, non-suppressible by Dp(1;3)CH322-4P16

      (Casas-Tintó and Ferrús, 2021)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Mutation in the haplo-lethal (HL) region of the Sh complex.

      (Ferrus et al., 1990)

      Mutation within the haplo-lethal (HL) region of the Sh complex.

      (de la Pompa, 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      l(1)13193
      (de la Pompa, 1994)
      l(1)13193DL
      (Casas-Tintó and Ferrús, 2021)
      wupA13193
      Name Synonyms
      Secondary FlyBase IDs
        References (3)