Allele Dmel\y^+mDint

General Information
Symbol	Dmel\y^+mDint	Species	D. melanogaster
Name		FlyBase ID	FBal0036048
Feature type	allele	Associated gene	Dmel\y

Allele class
Mutagen	in vitro construct - minigene, in vitro construct - deletion
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - deletion (Harrison et al., 1989) in vitro construct - minigene (Geyer and Corces, 1987)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Internal deletion removing the complete intron. (Harrison et al., 1989) Construct: Internal deletion removing the complete intron. (Geyer and Corces, 1987)
Carried in construct	P{dam⁺.phy705} (Boivin and Dura, 1998) P{Dint} (Geyer and Corces, 1987, Harrison et al., 1989) P{lyB} (Busseau and Bucheton, 1999) P{ninaE.Y126E} (Salcedo et al., 2003) P{ninaE.Y126F} (Salcedo et al., 2003) P{ninaE-LimRh1.1D4} (Knox et al., 2003) P{ninaE-LimRh1.K} (Knox et al., 2003) P{ninaE-Rh3.F133E} (Salcedo et al., 2003) P{ninaE-Rh3.F133Y} (Salcedo et al., 2003) P{ninaE-Rh3.K110E} (Salcedo et al., 2003) P{ninaE-Rh3.K110N} (Salcedo et al., 2003) P{ninaE-Rh5.A53Y} (Salcedo et al., 2003) P{ninaE-Rh5.D125Q.Y127F} (Salcedo et al., 2003) P{ninaE-Rh5.F147Y} (Salcedo et al., 2003) P{ninaE-Rh5.H38P.R42L} (Salcedo et al., 2003) P{ninaE-Rh5.I110Y} (Salcedo et al., 2003) P{ninaE-Rh5.N104K} (Salcedo et al., 2003) P{ninaE-Rh5.R243F} (Salcedo et al., 2003) P{ninaE-Rh5.S325A} (Salcedo et al., 2003) P{ninaE-Rh5.T173I.W176Y} (Salcedo et al., 2003) P{Rh1+5} (Chou et al., 1996) P{UAS-Alh.FLAG} (Perrin et al., 2003) P{UAS-Alh.L} (Perrin et al., 2003) P{UAS-Alh.L-PHD} (Perrin et al., 2003) P{UAS-Alh.LZ1} (Perrin et al., 2003) P{UAS-Alh.LZ2} (Perrin et al., 2003) P{UAS-Alh.L-Δ1-53} (Perrin et al., 2003) P{UAS-Alh.L-ΔLZ} (Perrin et al., 2003) P{UAS-Alh.L-ΔPHD} (Perrin et al., 2003) P{UAS-Alh.S} (Perrin et al., 2003) P{UAS-LZ-AF10} (Perrin et al., 2003) P{UAS-MLL.Nter} (Perrin et al., 2003) P{UAS-MLL-AF10} (Perrin et al., 2003) P{UAS-MLL-Alh} (Perrin et al., 2003) P{UAS-mor.LZ} (Perrin et al., 2003) P{UASy⁺} (Perrin et al., 2003) P{yhsPc} (Fauvarque et al., 1995) P{yhsph} (Fauvarque et al., 1995)
Cytology
Phenotypic Data
Phenotypic Class
	body color defective (Geyer and Corces, 1987)
Phenotype Manifest In
	arista (Drapeau et al., 2006) chaeta (Drapeau et al., 2006) macrochaeta (Geyer and Corces, 1987) sex comb (Drapeau et al., 2006) unguis (Drapeau et al., 2006)
Detailed Description
	Statement Reference The male mating success of y^+mDint males is statistically equivalent to controls. y^+mDint flies have greatly reduced pigmentation in the aristae and tarsal claws. They show a partial reduction in the bristles and sex combs. (Drapeau et al., 2006) Body colour: body, wing and sex combs wild-type on y^-; bristles, tarsal clawd and aristae yellow on y^-. Larval mouth part colour: intermediate on y^-. Larval denticle belt colour: yellow on y^-. (Harrison et al., 1989) Body colour: wild type, wing and sex combs wild type, bristles. Larval mouth part colour: reduced. Larval denticle belt colour: mutant. (Geyer and Corces, 1987)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Partially rescues	y^+mDint partially rescues y[-] (Geyer and Corces, 1987)
Comments
Stocks ( 17 )
Bloomington	9432 y¹ w^*; P{UAS-MLL.Nter}2 8646 y¹ w^67c23; P{UAS-Alh.S}3 9417 y¹ w^67c23; P{UAS-Alh.L}3 8639 y¹ w^67c23; P{UAS-mor.LZ}2 8634 y¹ w^67c23; P{UAS-LZ-AF10}2 9140 y¹ w^67c23; P{UAS-Alh.LZ1}3 9395 y¹ w^67c23; P{yhsPc}703.9.3 8637 y¹ w^67c23; P{UAS-Alh.L-PHD}2 8645 y¹ w^67c23; P{UAS-Alh.L-ΔLZ}2 9397 y¹ w^67c23; P{yhsph}704.1/CyO 8638 y¹ w^67c23; P{UAS-Alh.L-ΔPHD}3 8636 y¹ w^67c23; P{UAS-MLL-Alh}2/CyO
	More stocks available...
Notes on Origin
Discoverer

Comments
	Carried in plasmid pCiB-yⁱⁿ (which is designed to be a donor plasmid for recombinase-mediated cassette exchange (RMCE) using phiC31\int) and injected into D.melanogaster embryos. (Bateman et al., 2006)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	y^+mDint
Name Synonym
Secondary FlyBase IDs

References ( 13 )
Research paper	Gohl et al., 2008, Genetics 178(1): 127--143 Enhancer blocking and transvection at the Drosophila apterous Locus. [FBrf0202942] Bateman et al., 2006, Genetics 173(2): 769--777 Site-specific transformation of Drosophila via phiC31 integrase-mediated cassette exchange. [FBrf0194832] Drapeau et al., 2006, Genetics 172(2): 1009--1030 A cis-regulatory sequence within the yellow locus of Drosophila melanogaster required for normal male mating success. [FBrf0190716] Knox et al., 2003, J. Biol. Chem. 278(42): 40493--40502 Heterologous expression of Limulus rhodopsin. [FBrf0174768] Kuhn et al., 2003, EMBO J. 22(10): 2463--2471 A test of insulator interactions in Drosophila. [FBrf0158899] Perrin et al., 2003, Mol. Cell. Biol. 23(1): 119--130 The leucine zipper motif of the Drosophila AF10 homologue can inhibit PRE-mediated repression: implications for leukemogenic activity of human MLL-AF10 fusions. [FBrf0155962] Salcedo et al., 2003, J. Neurosci. 23(34): 10873--10878 Molecular basis for ultraviolet vision in invertebrates. [FBrf0167803] Busseau and Bucheton, 1999, D. I. S. 82: 94--95 A Drosophila enhancer detector transposon marked with the yellow gene. [FBrf0111819] Boivin and Dura, 1998, Genetics 150(4): 1539--1549 In vivo chromatin accessibility correlates with gene silencing in Drosophila. [FBrf0105778] Chou et al., 1996, Neuron 17(6): 1101--1115 Identification of a novel Drosophila opsin reveals specific patterning of the R7 and R8 photoreceptor cells. [FBrf0091031] Fauvarque et al., 1995, Mech. Dev. 52(2-3): 343--355 Regulation of polyhomeotic transcription may involve local changes in chromatin activity in Drosophila. [FBrf0083917] Harrison et al., 1989, Dev. Genet. 10: 239--248 The gypsy retrotransposon of Drosophila melanogaster: mechanisms of mutagenesis and interaction with the suppressor of Hairy-wing locus. [FBrf0049522] Geyer and Corces, 1987, Genes Dev. 1: 996--1004 Separate regulatory elements are responsible for the complex pattern of tissue-specific and developmental transcription of the yellow locus in Drosophila melanogaster. [FBrf0046293]

Allele Dmel\y+mDint

Allele Dmel\y^+mDint