Allele Ecol\lacZ^{P\T.T:Khc-606}

General Information
Symbol	Ecol\lacZ^{P\T.T:Khc-606}	Species	E. coli
Name		FlyBase ID	FBal0038885
Feature type	allele	Associated gene	Ecol\lacZ

Allele class
Mutagen	in vitro construct - regulatory fusion, in vitro construct - coding region fusion
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - coding region fusion (Giniger et al., 1993) in vitro construct - regulatory fusion (Giniger et al., 1993)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: A 1.9kb fragment encoding the first 606 amino acids of Khc is fused to a 3.4kb fragment of Ecol\lacZ which starts at the eighth codon. It is expressed under the control of a P\T promoter. (Giniger et al., 1993)
Carried in construct	P{KZ.TRAP} (Han et al., 2000, Rotoli et al., 1998, Steinhauer and Kalderon, 2005, Mohr et al., 2001, Martin and St. Johnston, 2003, Jan and Jan, 1993, Clark et al., 1994, Doronkin et al., 2002, Baum et al., 2000, MacDougall et al., 2001, Motola and Neuman-Silberberg, 2004, Giniger et al., 1993, Brent et al., 2000, Newmark et al., 1997, Jankovics et al., 2001, Micklem, 1995, Nakamura et al., 2004, Kolodziej et al., 1995, Styhler et al., 1998, Januschke et al., 2006, Coutelis and Ephrussi, 2007, Sun et al., 2011, Tian and Deng, 2008, Gervais et al., 2008, Krauss et al., 2009, Krauss et al., 2009, Becalska and Gavis, 2010, Yan et al., 2011, Sanghavi et al., 2012)
Tagged with	T:Khc-606 (Rotoli et al., 1998, Styhler et al., 1998, Han et al., 2000, Brent et al., 2000, Baum et al., 2000, MacDougall et al., 2001, Jankovics et al., 2001, Mohr et al., 2001, Doronkin et al., 2002, Martin and St. Johnston, 2003, Nakamura et al., 2004, Steinhauer and Kalderon, 2005, Jan and Jan, 1993, Giniger et al., 1993, Clark et al., 1994, Kolodziej et al., 1995, Micklem, 1995, Tio and Moses, 1997, Newmark et al., 1997)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
Bloomington	8766 y¹ w^*; P{KZ.TRAP}KZ1138
Notes on Origin
Discoverer

Comments
	Portion of Khc is sufficient to produce plus-end directed motor activity. (Clark et al., 1994) Fusion of the Ecol\lacZ gene to the Khc gene targets Ecol\lacZ expression to axons. (Giniger et al., 1993)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	Ecol\lacZ^{P\T.T:Khc-606} Ecol\lacZ^P\T.T:Khc Khc^T:lacZ lacZ^P\T.T:Khc
Name Synonym
Secondary FlyBase IDs

References ( 36 )

Generate a list of	All references relating to this allele ( 36 )

List References by type	Research paper ( 33 ) Supplementary material ( 1 ) Review ( 2 )
Recent research papers ( 3 )
	Sanghavi et al., 2012, Dev. Biol. 367(1): 66--77 A functional link between localized Oskar, dynamic microtubules, and endocytosis. [FBrf0218511] Sun et al., 2011, Development 138(10): 1991--2001 Regulation of somatic myosin activity by Protein Phosphatase 1{beta} controls Drosophila oocyte polarization. [FBrf0213586] Yan et al., 2011, Development 138(9): 1697--1703 Drosophila PI4KIIIalpha is required in follicle cells for oocyte polarization and Hippo signaling. [FBrf0213488] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...

Allele Ecol\lacZP\T.T:Khc-606

Allele Ecol\lacZ^{P\T.T:Khc-606}