FB2025_01 , released February 20, 2025
Allele: Dmel\RpL32+t3.3
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General Information
Symbol
Dmel\RpL32+t3.3
Species
D. melanogaster
Name
FlyBase ID
FBal0038903
Feature type
allele
Associated gene
Dmel\RpL32
Associated Insertion(s)
Carried in Construct
P{RP49}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Kongsuwan et al., 1985)
wild_type
(Kongsuwan et al., 1985)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Kongsuwan et al., 1985)
wild_type
(Kongsuwan et al., 1985)
Mutagen
in vitro construct
(Crozatier et al., 1992, Schweisguth et al., 1990, Tamate et al., 1990, Kongsuwan et al., 1985)
Progenitor genotype
Carried in construct
P{RP49}
Cytology
Description

A genomic 3.3kb fragment containing the gene for the large subunit ribosomal protein 49, plus about 0.6kb of downstream and about 2.1kb of upstream DNA.

(Kongsuwan et al., 1985)
Allele components
Component
Use(s)
Regulatory region(s)
RpL32
Encoded product / tool
RpL32
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3R:30,044,713..30,048,021 [-]
Comment:

Position of genomic fragment on reference sequence inferred by FlyBase curator based on author statement: A genomic 3.3kb fragment containing the gene plus about 0.6kb of downstream and about 2.1kb of upstream DNA.

(Kongsuwan et al., 1985)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Specifically suppresses the dominant phenotype of RpL32 mutations, both with respect to bristle phenotype and developmental rate.

      (Kongsuwan et al., 1985)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      RpL32+t3.3 rescues the Minute phenotype of Ts(YLt;3Lt)B81+Dp(3;1)67A.

      (Crozatier et al., 1992)
      Images (0)
      Mutant
      Wild-type
      Stocks (5)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Some inserts of this allele are less effective than others at suppressing the RpL32 phenotype.

      (Kongsuwan et al., 1985)

      RpL32 expression has been studied in flies carrying an extra copy of the RpL32 gene (RpL32+t3.3).

      (Tamate et al., 1990)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      RpL32+t3.3
      Name Synonyms
      Secondary FlyBase IDs
        References (5)