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General Information
Symbol
Dmel\Psce22
Species
D. melanogaster
Name
FlyBase ID
FBal0038968
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

One copy of Psce22 is unable to suppress position effect variegation (PEV) at the w locus caused by In(1)wm4.

One copy of Psce22 moderately suppresses the telomeric position effect (TPE) in stocks carrying a variegating P{hsp26-pt-T}39C-5 insertion at the telomere of the left arm of chromosome two.

Shows no dominant effect on telomeric Position Effect Variegation (PEV) in stocks carrying a variegating w+mW.hs allele at the telomeres of the second and third chromosome.

Lethal over Psc1, shows some degree of viability over deficiencies for the region. Adult survivors of transallelic combinations of "hopeful" alleles show homeotic phenotypes. The wing is often half or less their normal size, bulbous, arched upward and curved inward in the shape of a cashew nut. The posterior compartment of the wing is more severely affected than the anterior compartment. Alula can be reduced or missing, posterior wing margin is missing and the flanking wing blade is eroded. This homeotic phenotype resembles that of the Cbx mutations, and is dominantly enhanced by Su(z)24. Enhances z1 eye color.

No homeotic phenotype and the mutation cannot enhance the homeotic phenotypes of Pc group mutants (FBrf0049524).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement
Reference

Psc[+]/Psce22 is an enhancer of adult mesothoracic segment | ectopic phenotype of E(z)Trm

Psc[+]/Psce22 is an enhancer of adult prothoracic segment phenotype of E(z)Trm

Suppressor of
Statement
Reference

Psc[+]/Psce22 is a suppressor | partially of adult abdominal segment 4 | ectopic phenotype of E(z)Trm

Psc[+]/Psce22 is a suppressor | partially of adult abdominal segment 5 phenotype of E(z)Trm

Psc[+]/Psce22 is a suppressor | partially of adult metathoracic segment phenotype of E(z)Trm

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Psce22/Snr1E1 wings have an extra vein between veins L3 and L4 in 44% of cases.

Has no effect on the frequency of X-Y chromosome nondisjunction seen in Df(1)X-1-53B males.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
Comments
Comments

Member of the "hopeful" class of Psc alleles, i.e. shows some degree of viability in trans to at least one of the "hapless" alleles.

External Crossreferences and Linkouts ( 2 )
Crossreferences
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (12)