Allele Dmel\Scr^Scer\UAS.cAa

General Information
Symbol	Dmel\Scr^Scer\UAS.cAa	Species	D. melanogaster
Name	Saccharomyces cerevisiae UAS construct a of Andrew	FlyBase ID	FBal0039015
Feature type	allele	Associated gene	Dmel\Scr

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Andrew et al., 1994)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: Expression of Scr cDNA under influence of Scer\GAL4 UAS. (Andrew et al., 1994)
Carried in construct	P{UAS-Scr.A} (Andrew et al., 1994, Yao et al., 1999, Barmina et al., 2005, Maruyama et al., 2011, Papadopoulos et al., 2010)
Cytology
Phenotypic Data
Phenotypic Class
	visible, with Scer\GAL4^dpp.blk1 (Yao et al., 1999)
Phenotype Manifest In
	antenna, with Scer\GAL4^dpp.blk1 (Yao et al., 1999) embryonic/larval salivary gland \| ectopic, with Scer\GAL4^tub.PU (Maruyama et al., 2011) mesothoracic tarsal segment, with Scer\GAL4^rn-GAL4-5 (Barmina et al., 2005) mesothoracic tibial transverse bristle row \| ectopic, with Scer\GAL4^rn-GAL4-5 (Barmina et al., 2005) metathoracic tarsal bristle transverse row 2 \| ectopic, with Scer\GAL4^rn-GAL4-5 (Barmina et al., 2005) metathoracic tarsal segment, with Scer\GAL4^rn-GAL4-5 (Barmina et al., 2005) prothoracic tarsal segment, with Scer\GAL4^rn-GAL4-5 (Barmina et al., 2005) sex comb \| ectopic, with Scer\GAL4^rn-GAL4-5 (Barmina et al., 2005)
Detailed Description
	Statement Reference Expression of Scr[Scer\UAS.cAa] under the control of Scer\GAL4[tub.PU] results in ectopic salivary glands developing and invaginating in parasegments 0 and 1 (as well as the normal glands that develop in parasegment 2). (Maruyama et al., 2011) Expression of Scr^Scer\UAS.cAa, under the control of Scer\GAL4^rn-GAL4-5, results in formation of ectopic transverse bristle rows and sex combs on the distal basitarsus of T2 and T3 legs, and a reduction and fusion of the more distal tarsal segments in all three legs. (Barmina et al., 2005)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement Reference Scer\GAL4^dpp.blk1, Scr^Scer\UAS.cAa has visible phenotype, suppressible by hth^Scer\UAS.cPa/Scer\GAL4^dpp.blk1 (Yao et al., 1999)
Phenotype Manifest In
Suppressed by
Statement Reference Scer\GAL4^dpp.blk1, Scr^Scer\UAS.cAa has antenna phenotype, suppressible by hth^Scer\UAS.cPa/Scer\GAL4^dpp.blk1 (Yao et al., 1999)
Additional Comments
Genetic Interactions
Statement Reference Co-expression of hth^Scer\UAS.cPa partially suppresses the antenna to leg transformation phenotypes produced by ectopic expression of Scr^Scer\UAS.cAa driven by Scer\GAL4^dpp.blk1. The antennae produced are aristaless and occasionally duplicated, similar to the hth^Scer\UAS.cPa phenotype. (Yao et al., 1999)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer	D.J. Andrews.

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Scr^Scer\UAS.cAa Scr^UAS.cAa
Name Synonym	Saccharomyces cerevisiae UAS construct a of Andrew
Secondary FlyBase IDs

References ( 5 )
Research paper	Maruyama et al., 2011, PLoS ONE 6(6): e20901 Genome-Wide Analysis Reveals a Major Role in Cell Fate Maintenance and an Unexpected Role in Endoreduplication for the Drosophila FoxA Gene Fork Head. [FBrf0214025] Barmina et al., 2005, Dev. Biol. 288(2): 528--544 Sex- and segment-specific modulation of gene expression profiles in Drosophila. [FBrf0190088] Yao et al., 1999, Dev. Biol. 211(2): 268--276 A common mechanism for antenna-to-leg transformation in Drosophila: suppression of homothorax transcription by four HOM-C genes. [FBrf0111139] Andrew et al., 1994, EMBO J. 13(5): 1132--1144 Setting limits on homeotic gene function: restraint of Sex combs reduced activity by teashirt and other homeotic genes. [FBrf0068401]
Supplementary material	Papadopoulos et al., 2010, Proc. Natl. Acad. Sci. U.S.A. 107(9): Supporting Information. [FBrf0220957]

Allele Dmel\ScrScer\UAS.cAa

Allele Dmel\Scr^Scer\UAS.cAa