G195S | Dsor1-PA; G192S | Dsor1-PB
Reported as G192S in FBrf93573. Maps to G195S in the CDS encoded by the reference sequence. The difference is due to the use of an upstream splice acceptor in an upstream intron. The annotated version is supported by full length cDNA LD41207 (GB:AY058692). The site of the nucleotide substitution in the mutant was inferred by FlyBase based on the reported amino acid change.
Embryos derived from homozygous fs(1)M31901 females fail to develop structures posterior to the seventh abdominal segment as well as anterior-most structures, including the head skeleton. The posterior defect is significantly suppressed if the female is also carrying one copy of Dsor1Su1; an eighth abdominal segment is formed. This suppression is significantly reduced if the females are also carrying one copy of rl9, rl10a or Df(2R)rl10b. Enhances the tor11D phenotype; considerable numbers of embryos laid by females heterozygous for Dsor1Su1 and tor11D fail to hatch at 28oC.
Suppresses the morphological defects and sterility of asp1/aspDD3 mutants. Survival of embryos is increased, fewer have no nuclei. The asp1; Dsor1Su1 double mutant shows reduction in the frequency of aneuploid and polyploid figures compared to asp1 single mutants.
Completely suppresses the eye phenotype of phl1 hemizygotes. SosJC2 heterozygotes also hemizygous for Dsor1Su1 have 2.62 +/- 0.83 R7-like cells per ommatidium. Partly suppresses the sev6 phenotype; flies hemizygous for sev6 and Dsor1Su1 have an R7 photoreceptor cell in 28.7% of ommatidia. Partly suppresses the maternal tor4 phenotype; 80.3% of embryos derived from tor4 Dsor1Su1 females have an A8 segment. Does not significantly alter the EgfrE3 eye phenotype. Partly suppresses the Egfrf7 phenotype.