|Feature type||allele||Associated gene||Dmel\Su(H)|
|Map ( GBrowse )|
|Allele class||loss of function allele, amorphic allele - genetic evidence|
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|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
Nonsense mutation in codon 138.
Nucleotide substitution: A1226T. Amino acid replacement: K94@.
|Phenotype Manifest In|
The number of corpora cardiaca cells is normal in mutant embryos.
Su(H)/Su(H)[IB115] mutant tissues exhibit a loss of ptc-positive prohemocytes and the overproduction of differentiated plasmatocytes. By contrast, an increase is not observed in the crystal cell population in Su(H)/Su(H)[IB115] mutant lymph glands.
Homozygotes are lethal during pupal development. Heterozygous flies carrying out 10 training sessions to test memory of odours display a lower 24 hour memory in spaced training (rest periods between tasks) compared to control flies.
Lethality during the first day of pupal development. Supernumerary cells stained in mutant imaginal discs have adopted a sensory organ precursor (SOP) fate instead of the epidermal fate they would normally express. The excess SOPs arise from the proneural clusters of potential precursor cels that appear in the imaginal discs during the development of wild type bristles. The wing pouch region of the wing imaginal disc and the retinal field of the eye-antennal imaginal disc are dramatically reduced. Identical phenotype is seen when transheterozygous with Df(2L)TE35BC-24, Su(H)1, Su(H)2 or Su(H)8.
|Phenotype Manifest In|
Su(H)IB115 dominantly enhances the loss of microchaetae seen in NMcd1, NMcd5 or NMcd8 heterozygotes, reducing the number of microchaetae per heminotum to 64.00 +/- 1.84, 69.92 +/- 1.86 or 79.67 +/- 1.40 respectively.
|Complementation & Rescue Data|
|Stocks ( 1 )|
|Notes on Origin|
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 1 )|
|Secondary FlyBase IDs|
|References ( 15 )|
|Personal communication to FlyBase|