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General Information
Symbol
Dmel\Su(var)3-917
Species
D. melanogaster
Name
FlyBase ID
FBal0039075
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Deletion of 8bp within the open reading frame of a 2.4kb transcript.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

No abdominal dorsal fusion defects are seen in Su(var)3-917 males.

Strong suppressors of bw and w position effect variegation (PEV).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
Enhancer of
Statement
Reference

Su(var)3-917 is an enhancer of visible | adult stage | temperature conditional phenotype of crm32

Suppressor of
Statement
Reference

Su(var)3-917 is a suppressor of visible | adult stage | temperature conditional phenotype of crm32

Phenotype Manifest In
Enhancer of
Statement
Reference

Su(var)3-917 is an enhancer of adult abdomen | temperature conditional phenotype of crm32

Suppressor of
Statement
Reference

Su(var)3-917 is a suppressor of sex comb | increased number | temperature conditional phenotype of crm32

Su(var)3-9[+]/Su(var)3-917 is a suppressor of eye phenotype of DlUAS.cDa, Scer\GAL4ey.PH, lolaGS88A8, psqGS88A8

Other
Additional Comments
Genetic Interactions
Statement
Reference

Su(var)3-917 enhances the abdominal dorsal fusion defects seen in crm32 mutants; unlike in crm32 alone, dorsal fusion phenotypes are visible at 25[o]C. In contrast the crm32 ectopic sex comb phenotype is suppressed.

eggG19561; Su(var)3-917 double mutants mostly exhibit a gourd-shaped germaria and defects in the budding off of new egg chambers; as a result, the double mutant has no developing egg chambers in the ovary.

Su(var)3-917 dominantly suppresses the eye tumour phenotype of flies expressing DlScer\UAS.cDa under the control of Scer\GAL4ey.PH and also carrying the P{GSV1}lolaGS88A8 insertion (which results in the lolaGS88A8 and psqGS88A8 alleles being expressed under the control of Scer\GAL4ey.PH).

Has no effect on the frequency of X-Y chromosome nondisjunction seen in Df(1)X-1-53B males.

Xenogenetic Interactions
Statement
Reference

The addition of Hsap\SUV39Hhs.T:Avic\GFP-EGFP partially complements the suppression of PEV phenotype seen in Su(var)3-917 animals.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 1 )
Crossreferences
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (9)