Allele Dmel\Wow^γb

General Information
Symbol	Dmel\Wow^γb	Species	D. melanogaster
Name		FlyBase ID	FBal0039116
Feature type	allele	Associated gene	Dmel\Wow
Also Known As	Wow<up>gamma b</up>

Allele class
Mutagen
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| recessive (Pal Bhadra et al., 1998) sterile \| recessive (Birchler et al., 1994) visible \| recessive (Birchler et al., 1994)
Phenotype Manifest In
	Malpighian tubule (Birchler et al., 1994) pigment cell (Birchler et al., 1994, Pal Bhadra et al., 1998) testis (Birchler et al., 1994) wing (Birchler et al., 1994)
Detailed Description
	Statement Reference In a w⁺ background the Wow homozygotes have a discernibly visible reduction in eye pigmentation, which is nevertheless still near the wild type colour. Wow increases pigment levels in the Malpighian tubules and testes. This increase is more marked for Wow homozygotes than for Wow heterozygotes. The wings of Wow mutant homozygotes are reduced and sometimes do not fully expand. Males and females are sterile. In some backgrounds mutants are only semi-viable, with the semi-lethality being more pronounced for males than females. (Birchler et al., 1994)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement Reference Wow^γb has phenotype, suppressible by Low¹ (Pal Bhadra et al., 1998)
Enhancer of
Statement Reference Wow^γb is an enhancer of phenotype of w^+mC (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^a59k1 (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^a (Pal Bhadra et al., 1998, Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^aM (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^aR84h (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^bl (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^Bwx (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^cf (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^co (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^col (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^DZL (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^IR1 (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^IR2 (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^IR3 (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^IR4 (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^IR5 (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^IR6 (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^is (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^ric (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^sat (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^sp1 (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^sp2 (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^sp4 (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^zl (Birchler et al., 1994) Wow^γb is an enhancer of phenotype of w^zm (Birchler et al., 1994)
NOT Enhancer of
Statement Reference Wow^γb is a non-enhancer of phenotype of lt^X84 (Birchler et al., 1994) Wow^γb is a non-enhancer of phenotype of w^Adh.PB (Birchler et al., 1994) Wow^γb is a non-enhancer of phenotype of w^apl (Birchler et al., 1994) Wow^γb is a non-enhancer of phenotype of w^bf2 (Birchler et al., 1994) Wow^γb is a non-enhancer of phenotype of w^c (Birchler et al., 1994) Wow^γb is a non-enhancer of phenotype of w^e (Birchler et al., 1994) Wow^γb is a non-enhancer of phenotype of w^h (Birchler et al., 1994) Wow^γb is a non-enhancer of phenotype of wⁱ (Birchler et al., 1994)
Suppressor of
Statement Reference Wow^γb is a suppressor of phenotype of Low¹ (Pal Bhadra et al., 1998) Wow^γb is a suppressor of phenotype of w^+mF (Birchler et al., 1994) Wow^γb is a suppressor of phenotype of w^a2 (Birchler et al., 1994) Wow^γb is a suppressor of phenotype of w^a3 (Birchler et al., 1994) Wow^γb is a suppressor of phenotype of w^a4 (Birchler et al., 1994) Wow^γb is a suppressor of phenotype of w^bf (Birchler et al., 1994) Wow^γb is a suppressor of phenotype of w^E (Birchler et al., 1994)
NOT Suppressor of
Statement Reference Wow^γb is a non-suppressor of phenotype of lt^X84 (Birchler et al., 1994) Wow^γb is a non-suppressor of phenotype of w^Adh.PB (Birchler et al., 1994) Wow^γb is a non-suppressor of phenotype of w^apl (Birchler et al., 1994) Wow^γb is a non-suppressor of phenotype of w^bf2 (Birchler et al., 1994) Wow^γb is a non-suppressor of phenotype of w^c (Birchler et al., 1994) Wow^γb is a non-suppressor of phenotype of w^e (Birchler et al., 1994) Wow^γb is a non-suppressor of phenotype of w^h (Birchler et al., 1994) Wow^γb is a non-suppressor of phenotype of wⁱ (Birchler et al., 1994)
Additional Comments
Genetic Interactions
Statement Reference The effect of Inr-a^EMS2 is epistatic to that of Wow^γb and Mow^EMS. Low¹ and Wow^γb mutually suppress the effect of the other. (Pal Bhadra et al., 1998) In the presence of w^a the eye color is reduced to that found in a female homozygous for a w deficiency. In the Wow mutant homozygotes the w^a allele is reduced further to an almost w phenotype. (Birchler et al., 1994)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Wow<up>gamma b</up> (Pal Bhadra et al., 1998, Birchler et al., 1994) Wow^γb
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Pal Bhadra et al., 1998, Mol. Gen. Genet. 259(2): 198--206 Role of multiple trans-acting regulators in modifying the effect of the retrotransposon copia on host gene expression in Drosophila. [FBrf0104493] Birchler et al., 1994, Genetics 137(4): 1057--1070 Weakener of white (Wow), a gene that modifies the expression of the white eye color locus and that suppresses position effect variegation in Drosophila melanogaster. [FBrf0074960]

Allele Dmel\Wowγb

Allele Dmel\Wow^γb