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General Information
Symbol
Dmel\bs14
Species
D. melanogaster
Name
FlyBase ID
FBal0039185
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:
C24344393T
Reported nucleotide change:
C?T
Amino acid change:
Q102term | bs-PA; Q102term | bs-PB; Q102term | bs-PC
Reported amino acid change:
Q102term
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Amino acid replacement: Q102term.
Mutation lies before the MADS domain.
Nucleotide substitution: C?T.
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Heterozygotes have ectopic vein tissue in the wing.
bs14 homozygous clones in the dorsal air sac primordium grow normally and populate the tip of the air sac primordium to the same degree as wild-type clones
bs14 embryos show defects in the tracheal system at stage 16, having truncated terminal branches (about 95% penetrance).
In homozygotes, lethality acts at the 2nd or 3rd larval instar. Mutants show a tracheal phenotype similar to that of bs03267. When heterozygous with wild type, a few additional veins develop.
Mosaic analysis shows that the effect of bs14 is autonomous with respect to the effects on cell size: cells are considerably smaller. However dorsal veins overlying ventral clones are widened and blisters extend beyond clone borders.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
bs14 has visible | dominant phenotype, enhanceable by tx33-2/tx[+]
Phenotype Manifest In
Enhanced by
Statement
Reference
bs14 has wing vein | ectopic phenotype, enhanceable by tx33-2/tx[+]
Additional Comments
Genetic Interactions
Statement
Reference
The extra wing vein phenotype of bs14/+ flies is more pronounced if they are also carrying tx33-2/+.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments
Chromosome carrying bs14 is larval lethal but the basis for the lethality is not clear, though it does map within Df(2R)Px2. Alleles fall into a series in ascending order of severity: bsA48 < bs11 < bs12 < bs13 < bs14 < Df(2R)bs-F31.
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (7)