argosΔ7/argosW11 flies have blisters in the eye.
Only 5% of eggs derived from argosΔ7/argosW11 have defects in dorsal appendage morphology, which include a reduced distance between the two appendages and appendages that are shorter than normal.
Heterozygotes show a direct effect on the shape of the wing.
When homozygous mutant clones are made in the eye, although many of the mutant ommatidia have too many photoreceptors, a significant proportion have the correct number. many of these ommatidia are misrotated.
Mutant eye discs show, in addition to the extra R-cell phenotype, severe ommatidial rotation defects, though the initial 45oC rotation seen in wild-type is less affected.
argosΔ7/argosW11 hypomorphic females lay a significant proportion of eggs with fused dorsal appendages. Larvae hatch from the eggs, with dorsal-ventral pattern unperturbed.
The number of midline glia cells is increased to an average of 5.1 +/- 0.2 cells per segment in homozygous embryos.
Retinal degeneration in aging flies.
Mutant ommatidia have extra pigment cells.
Reduced viability and rough eye phenotype, including blistering in the posterior region of the eye due to a lawn of undifferentiated cells in the pupal eye. Eyes have abnormal rhabdomere morphology and extra outer photoreceptors. Optic lobes are small and disorganised. Many of the mystery cells start differentiating as neurons and never leave the developing ommatidia. Extra cone cells and an abnormally high number of primary pigment cells are found in the pupal eye. Interommatidial bristle precursors are disorganised though the total number appears to be normal.