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General Information
Symbol
Dmel\lola1A4
Species
D. melanogaster
Name
FlyBase ID
FBal0039613
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{lacW}lola1A4
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Fas2-expressing axons are seen crossing back and forth across the midline in mutant embryos, in contrast to wild type.
In mutant embryos, the motor axons that project through the SNb peripheral nerve fail to form connections to their cognate muscles. Most commonly, SNb axons appear to "stall" somewhere between the point at which they would normally separate from the ISN and the muscle 6/13 junction. In other hemisegments, SNb axons project through the muscles field but fail to branch into the intermuscle clefts where synapses should be formed. The phenotype is slightly weaker than seen in lola5D2. In mutant embryos neuronal and muscle cell identities are normal. The overall pattern of muscle morphologies and attachments are for the most part normal, though with low penetrance ventral longitudinal muscles can be missing.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
lola1A4
Name Synonyms
Secondary FlyBase IDs
    References (3)