Allele Scer\FLP1^hs.PG

General Information
Symbol	Scer\FLP1^hs.PG	Species	S. cerevisiae
Name	heat shock construct of Golic	FlyBase ID	FBal0040456
Feature type	allele	Associated gene	Scer\FLP1

Allele class
Mutagen	in vitro construct - coding region fusion, in vitro construct - regulatory fusion
Recent Updates
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FB2013_03	Stocks FBst0043660
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - coding region fusion (Golic and Lindquist, 1989) in vitro construct - regulatory fusion (Chou and Perrimon, 1992, Xu and Rubin, 1993, Melnick et al., 1993, Peifer et al., 1993, Ito et al., 1997)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference An Hsp70 promoter drives Scer\FLP1 expression. (Ito et al., 1997) Scer\FLP1 recombinase gene expression is driven by an Hsp70 promoter. (Heberlein et al., 1993) Construct: Scer\FLP1 recombinase gene expression is driven by an Hsp70 promoter. (Xu and Rubin, 1993) Scer\FLP1 expression is driven by an Hsp70 promoter. (Chou and Perrimon, 1992) Scer\FLP1 gene expression is driven by a heat shock promoter. (Golic and Lindquist, 1989, Melnick et al., 1993, Peifer et al., 1993, Ramain et al., 1993)
Carried in construct	P{hsFLP} (Xu and Rubin, 1993, Zhu et al., 2003, Keller et al., 2002, Ahmad and Golic, 1998, Peifer et al., 1993, Heberlein et al., 1993, Harrison and Perrimon, 1993, Melnick et al., 1993, Simpson, 1993, Rauskolb and Wieschaus, 1994, Zusman et al., 1994, Nicolai et al., 2003, Lin et al., 1995, Ramain et al., 1993, Menne and Klambt, 1994, Justice et al., 1995, Heberlein et al., 1995, Smith et al., 1993, Xu et al., 1995, Hsu and Perrimon, 1994, Peifer et al., 1994, Rusch and Levine, 1994, Jhaveri et al., 2000, Golic, 1994, Martin-Bermudo et al., 1995, Luo et al., 1999, Sun and Tower, 1999, Lecuit and Cohen, 1998, Lee and Luo, 1999, Busturia et al., 1997, Tanentzapf et al., 2000, Parnell and Geyer, 2000, Golic et al., 1997, Chou and Perrimon, 1992, Dang and Perrimon, 1992, Golic, 1991, Golic and Lindquist, 1989, Chen and Struhl, 1998, Johnston et al., 1998, Xie and Spradling, 1998, Margolis and Spradling, 1995, Penton and Hoffmann, 1996, Chanut and Heberlein, 1995, Burke and Basler, 1996, Ng et al., 1996, Nellen et al., 1996, Lecuit et al., 1996, Curtiss and Heilig, 1995, Treisman and Rubin, 1995, Tabata et al., 1995, Hart and Bienz, 1996, Doherty et al., 1996, Soto et al., 1995, Buenzow and Holmgren, 1995, Melendez et al., 1995, Diaz-Benjumea and Cohen, 1995, Welte et al., 1993, Ahmad and Golic, 1996, Smith et al., 1996, Strutt and Mlodzik, 1996, Lecuit and Cohen, 1997, Fedorova et al., 1997, Yang et al., 1997, Pai et al., 1998, Perrimon et al., 1996, Chou and Perrimon, 1996, Gonczy and DiNardo, 1996, Rusch and Levine, 1997, Okabe and Okano, 1997, Penton et al., 1997, Ito et al., 1997, Lee et al., 1997, Buescher and Chia, 1997, Brook and Cohen, 1996, de Cuevas et al., 1996, Morimoto et al., 1996, Gong and Golic, 2003, LaLonde et al., 2006, Mitonaka et al., 2007, Boto et al., 2010, Yuan et al., 2011, Awasaki et al., 2008, Thum et al., 2011, Hung et al., 2011, Zhang et al., 2012, Stephan et al., 2011, Shen et al., 2008, Yan et al., 2009, Rakovitsky et al., 2007, Juhász et al., 2008, Cheng et al., 2010, Molnar et al., 2011, Hadjieconomou et al., 2011, Poulton et al., 2011, Singh and Mlodzik, 2012, Pircs et al., 2012, Roch et al., 2010, Elsaesser et al., 2010, Zheng et al., 2010, Biteau et al., 2010, Mathur et al., 2010, Griffin et al., 2009, Silicheva et al., 2010, Hudson and Cooley, 2010, Haruta et al., 2010, Gurudatta et al., 2010)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference All flies bearing Scer\FLP1^hs.PG become mosaic at 38.5^oC, a lower temperature reduces the number of mosaics. (Golic and Lindquist, 1989)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 66 )
Bloomington	8862 P{hsFLP}22, w^* 6 P{hsFLP}1, w¹¹¹⁸; Adv¹/CyO 9675 P{hsFLP}22, y¹ w^; P{UAS-dm.Z}42 7012 y¹ w^ P{hsFLP}1; P{UAS-Tor.WT}III 279 w¹¹¹⁸; MKRS, P{hsFLP}86E/TM6B, Tb¹ 5132 P{hsFLP}1, P{tubP-GAL80}LL1 w^* P{neoFRT}19A 1929 P{hsFLP}12, y¹ w^*; sna^Sco/CyO
Kyoto	105670 P{hsFLP}1, w¹¹¹⁸; Adv¹/CyO 105829 w¹¹¹⁸; MKRS, P{hsFLP}86E/TM6B, Tb¹ 108063 P{neoFRT}19A, P{tubP-GAL80}LL1, P{hsFLP}1, w^* 106583 P{hsFLP}12, y¹ w^; sna^Sco/CyO 101876 y^ w^* P{hsFLP}12; CyO / sna^Sco
	More stocks available...
Notes on Origin
Discoverer	Golic Golic Golic Golic Xu Golic Golic Golic and Lindquist

Comments
	Transient transfection assay in DH33 cultured cells. (Smith et al., 1996) There is a low level of constitutive expression. Recombinase is active in the somatic cells and the germline producing white-eyed and dark red-eyed progeny. (Golic and Lindquist, 1989)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	FLP1^hs.PG hs-FLP (Lee and Luo, 1999) Scer\FLP1^hs.PG
Name Synonym	heat shock construct of Golic (Golic and Lindquist, 1989)
Secondary FlyBase IDs
	FBal0042546
References ( 128 )

Generate a list of	All references relating to this allele ( 128 )

List References by type	Research paper ( 125 ) Supplementary material ( 1 ) Review ( 1 ) Abstract ( 1 )
Recent research papers ( 10 )
	Pircs et al., 2012, PLoS ONE 7(8): e44214 Advantages and Limitations of Different p62-Based Assays for Estimating Autophagic Activity in Drosophila. [FBrf0219364] Singh and Mlodzik, 2012, Dev. Cell 23(1): 82--96 Hibris, a Drosophila Nephrin Homolog, Is Required for Presenilin-Mediated Notch and APP-like Cleavages. [FBrf0218978] Zhang et al., 2012, PLoS ONE 7(2): e31994 Control of tissue growth and cell transformation by the salvador/warts/hippo pathway. [FBrf0217552] Hadjieconomou et al., 2011, Nat. Methods 8(3): 260--266 Flybow: genetic multicolor cell labeling for neural circuit analysis in Drosophila melanogaster. [FBrf0213120] Hung et al., 2011, Science 334(6063): 1710--1713 Direct redox regulation of F-actin assembly and disassembly by Mical. [FBrf0217252] Molnar et al., 2011, PLoS Genet. 7(3): e1001335 Role of the Drosophila non-visual ß-arrestin kurtz in hedgehog signalling. [FBrf0213301] Poulton et al., 2011, Development 138(9): 1737--1745 The microRNA pathway regulates the temporal pattern of Notch signaling in Drosophila follicle cells. [FBrf0213494] Stephan et al., 2011, Mol. Biol. Cell 22(21): 4079--4092 Membrane-targeted WAVE mediates photoreceptor axon targeting in the absence of the WAVE complex in Drosophila. [FBrf0216499] Thum et al., 2011, J. Comp. Neurol. 519(17): 3415--3432 Diversity, variability, and suboesophageal connectivity of antennal lobe neurons in D. melanogaster larvae. [FBrf0216269] Yuan et al., 2011, Science 333(6048): 1458--1462 Light-induced structural and functional plasticity in Drosophila larval visual system. [FBrf0215276] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...

Allele Scer\FLP1hs.PG

Allele Scer\FLP1^hs.PG