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General Information
Symbol
Scer\GAL4sca-537.4
Species
S. cerevisiae
Name
FlyBase ID
FBal0040466
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
sca-Gal4, scabrous-GAL4, ScaGAL4, sca::Gal4, scabrousGAL4, Scabrous GAL4, sca537.4
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{GawB}sca537.4
Product class / Tool use(s)
Expression Data
Reporter Expression
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Drives expression in proneural clusters and sensory mother cells.

During late larval and prepupal wing development, sca is expressed in a stripe adjacent to the anterior-posterior (A/P) compartment boundary on the anterior side (primordia of the L3 vein) and two stripes bracketing the entire presumptive margin.

Expression is observed in proneural clusters in the wing disc.

 
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

abdominal ventral longitudinal muscle 1 & neuromuscular junction, with acj61,3,4.UAS

abdominal ventral longitudinal muscle 2 & neuromuscular junction, with acj61,3,4.UAS

abdominal ventral longitudinal muscle 3 & neuromuscular junction, with acj61,3,4.UAS

abdominal ventral longitudinal muscle 4 & neuromuscular junction, with acj61,3,4.UAS

aCC neuron & synapse, with Ctet\tetXTNT-LC.UAS

adult abdomen & macrochaeta, with E(spl)m8-HLH1,stop.UAS

adult abdomen & macrochaeta, with E(spl)m8-HLH1.UAS

adult abdomen & macrochaeta, with E(spl)m8-HLHUAS.cGa

adult abdomen & macrochaeta, with E(spl)m8-HLHΔbHIII.UAS

adult abdomen & macrochaeta, with E(spl)m8-HLHΔbHIV.UAS

adult abdomen & macrochaeta, with E(spl)m8-HLHΔbHLH.UAS

adult abdomen & macrochaeta, with grpEP587

adult abdomen & macrochaeta, with MESR4EP386

adult abdomen & macrochaeta, with MESR4EP988

adult abdomen & microchaeta, with bchsEP2299

adult abdomen & microchaeta, with Kr-h1EP2289

adult abdomen & trichogen cell, with aopEP598

adult abdominal sensillum & trichogen cell, with fafEP381

adult head & macrochaeta, with E(spl)m8-HLH1.UAS

adult head & macrochaeta, with E(spl)m8-HLHP-L.UAS

adult head & macrochaeta, with E(spl)m8-HLHUAS.cGa

adult thorax & chaeta, with sggS9A.UAS

adult thorax & chaeta, with sggS9E.UAS

adult thorax & chaeta, with sggUAS.cBa

adult thorax & mechanosensory sensory organ, with nvyUAS.cWa

adult thorax & microchaeta, with sggUAS.cBa

anterior fascicle & motor neuron, with acj61,3,4.UAS

axon & mechanosensory neuron & adult head, with htlAB42, htlDN.UAS.cMb

axon & mechanosensory neuron & adult head, with htlDN.UAS.cMb

axon & ocellus sensory structure, with EgfrDN.UAS.cBa

axon & ocellus sensory structure, with htlAB42, htlDN.UAS.cMb

axon & ocellus sensory structure, with htlDN.UAS.cMb

bract & leg | ectopic, with spis.UAS

chaeta & mesothoracic tergum | ectopic, with AbiUAS.Tag:Myr(Src64B)

external sensory organ precursor cell & dorsal mesothoracic disc, with BobAUAS.cLa

external sensory organ precursor cell & dorsal mesothoracic disc, with TomUAS.cLa

eye photoreceptor cell & eye disc | posterior, with DlM619S.K620R.H2N.UAS

eye photoreceptor cell & eye disc | posterior, with SerY1248S.F2I.UAS

macrochaeta & abdomen & pupa, with Cele\ced-3UAS.cSa

macrochaeta & abdominal sternite 1, with l(1)scUAS.cHa

macrochaeta & abdominal sternite 2, with l(1)scUAS.cHa

macrochaeta & abdominal sternite 3, with l(1)scUAS.cHa

macrochaeta & abdominal sternite 4, with l(1)scUAS.cHa

macrochaeta & abdominal sternite 5, with l(1)scUAS.cHa

macrochaeta & abdominal sternite 6, with l(1)scUAS.cHa

macrochaeta & adult head, with E(spl)m2-BFMUAS.cLa

macrochaeta & head, with neurUAS.cLa

macrochaeta & head, with neurUAS.L.Tag:MYC

macrochaeta & head & pupa, with Cele\ced-3UAS.cSa

macrochaeta & mesothoracic tergum, with AmunGD9779

macrochaeta & mesothoracic tergum, with AmunUAS.mRFP1

macrochaeta & mesothoracic tergum, with E(spl)m2-BFMUAS.cLa

macrochaeta & mesothoracic tergum, with egrGS9830

macrochaeta & mesothoracic tergum, with rprUAS.cIa

macrochaeta & mesothoracic tergum | ectopic, with AmunGD9779

macrochaeta & mesothoracic tergum | ectopic, with AmunUAS.mRFP1

macrochaeta & mesothoracic tergum | supernumerary, with AmunGD9779

macrochaeta & mesothoracic tergum | supernumerary, with AmunUAS.mRFP1

macrochaeta & scutellum, with egrGS9830

macrochaeta & scutellum, with rprUAS.cIa

macrochaeta & scutum, with esgEP684

macrochaeta & scutum, with esgEP2009

macrochaeta & scutum & pupa, with Cele\ced-3UAS.cSa

macrochaeta & tergum, with rprUAS.cIa

macrochaeta & thorax, with tantUAS.cDa

macrochaeta & thorax | supernumerary, with Dl::SerDl-E.Ser-I.UAS

macrochaeta & thorax | supernumerary, with SerY1248S.F2I.UAS

mesothoracic tarsal segment 1 & bract, with aosUAS.cHa

mesothoracic tarsal segment 1 & bract, with EgfrUAS.cBa

mesothoracic tarsal segment 1 & bract | ectopic, with spis.UAS

mesothoracic tergum & macrochaeta, with chndsRNA.UAS

mesothoracic tergum & macrochaeta, with Hsap\EZR1-280.UAS.GFP

microchaeta & leg, with TomUAS.cLa

microchaeta & scutum, with esgEP684

microchaeta & scutum, with esgEP2009

microchaeta & scutum, with hbsUAS.cDa

microtubule cytoskeleton & axon, with β-SpecdsRNA.UAS

neuron & embryonic abdomen | ectopic, with CycEUAS.cLa

neuron & embryonic thorax, with dapUAS.cLa

neuron & embryonic thorax, with Hsap\CDKN1AUAS.cHa

RP2 neuron & synapse, with Ctet\tetXTNT-LC.UAS

scutellum & microchaeta, with emcEP415

scutum & macrochaeta, with RalaS25N.UAS

scutum & macrochaeta & adult, with E(spl)m8-HLH1,stop.UAS

scutum & macrochaeta & adult, with E(spl)m8-HLH1.UAS

scutum & macrochaeta & adult, with E(spl)m8-HLH+,stop.UAS

scutum & macrochaeta & adult, with E(spl)m8-HLHbHLH.UAS

scutum & macrochaeta & adult, with E(spl)m8-HLHUAS.cGa

scutum & macrochaeta & adult, with E(spl)m8-HLHΔbHIV.UAS

scutum & macrochaeta & adult, with E(spl)m8-HLHΔbHLH.UAS

scutum & macrochaeta & tormogen cell, with RalaS25N.UAS

scutum & macrochaeta & trichogen cell, with RalaS25N.UAS

scutum & microchaeta, with BrdUAS.cLa

scutum & microchaeta, with RalaS25N.UAS

scutum & microchaeta & tormogen cell, with RalaS25N.UAS

scutum & microchaeta & trichogen cell, with RalaS25N.UAS

scutum & microchaeta | medial, with araUAS.cGa

scutum & microchaeta | medial, with caupUAS.cdCa

taste bristle & leg | ectopic, with aosUAS.cHa

taste bristle & leg | ectopic, with EgfrUAS.cBa

taste bristle & leg | ectopic, with spis.UAS

thecogen cell & actin filament & pupa, with HemUAS.Tag:Myr(Src64B)

Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

EgfrUAS.cUa, Scer\GAL4sca-537.4 has visible phenotype, enhanceable by pum01688/pum[+]

EgfrUAS.cUa, Scer\GAL4sca-537.4 has visible phenotype, enhanceable by pumMsc/pum[+]

NakUAS.cCa, Scer\GAL4sca-537.4 has visible phenotype, enhanceable by numb[+]/numb1

NOT Enhanced by
Statement
Reference

RalaS25N.cMa.UAS, Scer\GAL4sca-537.4 has visible phenotype, non-enhanceable by DreddB118/Dredd[+]

RalaS25N.cMa.UAS, Scer\GAL4sca-537.4 has visible phenotype, non-enhanceable by Dredd[+]/DreddL23

Suppressed by
Statement
Reference
NOT suppressed by
Statement
Reference

RalaS25N.cMa.UAS, Scer\GAL4sca-537.4 has visible phenotype, non-suppressible by DreddB118/Dredd[+]

RalaS25N.cMa.UAS, Scer\GAL4sca-537.4 has visible phenotype, non-suppressible by Dredd[+]/DreddL23

Scer\GAL4sca-537.4, dbrEP456 has visible phenotype, non-suppressible by H[+]/HE21

Scer\GAL4sca-537.4, tweEP613 has visible phenotype, non-suppressible by H[+]/HE21

Scer\GAL4sca-537.4, aopEP598 has visible phenotype, non-suppressible by H[+]/HE21

Scer\GAL4sca-537.4, stgEP1213 has visible phenotype, non-suppressible by H[+]/HE21

Scer\GAL4sca-537.4, qsmEP2356 has visible phenotype, non-suppressible by H[+]/HE21

Scer\GAL4sca-537.4, pblEP3415 has visible phenotype, non-suppressible by H[+]/HE21

BxEP1383, Scer\GAL4sca-537.4 has visible phenotype, non-suppressible by H[+]/HE21

Scer\GAL4sca-537.4, wdbEP3559 has visible phenotype, non-suppressible by H[+]/HE21

Scer\GAL4sca-537.4, sdEP1435 has visible phenotype, non-suppressible by H[+]/HE21

RalaS25N.UAS, Scer\GAL4sca-537.4 has visible phenotype, non-suppressible by rl9

Enhancer of
Statement
Reference
NOT Enhancer of
Suppressor of
Statement
Reference
NOT Suppressor of
Phenotype Manifest In
Enhanced by
Statement
Reference

EgfrUAS.cUa, Scer\GAL4sca-537.4 has macrochaeta | ectopic phenotype, enhanceable by pumMsc/pum[+]

Scer\GAL4sca-537.4, htlDN.UAS.cMb has axon & mechanosensory neuron & adult head phenotype, enhanceable by Egfr[+]/Egfrunspecified

NakUAS.cCa, Scer\GAL4sca-537.4 has wing sensillum phenotype, enhanceable by numb[+]/numb1

NakUAS.cCa, Scer\GAL4sca-537.4 has head sensillum phenotype, enhanceable by numb[+]/numb1

NOT Enhanced by
Statement
Reference

Scer\GAL4sca-537.4, htlDN.UAS.cMb has axon & ocellus sensory structure phenotype, non-enhanceable by EgfrE3/Egfr[+]

Suppressed by
Statement
Reference

Scer\GAL4sca-537.4, nvyUAS.cWa has adult thorax & mechanosensory sensory organ phenotype, suppressible by sensUAS.cNa

Scer\GAL4sca-537.4, htlDN.UAS.cMb has axon & ocellus sensory structure phenotype, suppressible by Egfr[+]/Egfrunspecified

RalaS25N.UAS, Scer\GAL4sca-537.4 has scutum & macrochaeta phenotype, suppressible by hep[+]/hepr75

RalaS25N.UAS, Scer\GAL4sca-537.4 has scutum & macrochaeta phenotype, suppressible by hep[+]/hep1

RalaS25N.UAS, Scer\GAL4sca-537.4 has scutum & macrochaeta phenotype, suppressible by bskflp147E/bsk[+]

RalaS25N.UAS, Scer\GAL4sca-537.4 has scutum & macrochaeta phenotype, suppressible by bsk2/bsk[+]

RalaS25N.UAS, Scer\GAL4sca-537.4 has scutum & macrochaeta phenotype, suppressible by bsk1/bsk[+]

NOT suppressed by
Statement
Reference

Scer\GAL4sca-537.4, htlDN.UAS.cMb has axon & mechanosensory neuron & adult head phenotype, non-suppressible by EgfrE3/Egfr[+]

Enhancer of
Statement
Reference
NOT Enhancer of
Statement
Reference
Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference

edΔECD.UAS/Scer\GAL4sca-537.4 is a non-suppressor of microchaeta | heat sensitive phenotype of NECN.hs

edΔECD.UAS/Scer\GAL4sca-537.4 is a non-suppressor of microchaeta | heat sensitive phenotype of Nicd.hs

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Fails to rescue
Comments

Neuroblast-specific expression of α-AdaptinScer\UAS.T:Avic\GFP via Scer\GAL4insc-Mz1407 completely rescues the brain tumor phenotype of α-AdaptinSH0460.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
GAL4sca-537.4
GAL4sca-H
Scer\GAL4sca-537.4
Name Synonyms
Secondary FlyBase IDs
  • FBal0040488
  • FBal0061869
References (169)