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General Information
Symbol
Scer\GAL4sca-537.4
Species
S. cerevisiae
Name
FlyBase ID
FBal0040466
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
sca-Gal4, scabrous-GAL4, ScaGAL4, sca::Gal4, scabrousGAL4, Scabrous GAL4, sca537.4
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{GawB}sca537.4
Product class / Tool use(s)
Expression Data
Reporter Expression
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference
Drives expression in proneural clusters and sensory mother cells.
During late larval and prepupal wing development, sca is expressed in a stripe adjacent to the anterior-posterior (A/P) compartment boundary on the anterior side (primordia of the L3 vein) and two stripes bracketing the entire presumptive margin.
Expression is observed in proneural clusters in the wing disc.
 
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
abdominal ventral longitudinal muscle 1 & neuromuscular junction, with acj61,3,4.UAS
abdominal ventral longitudinal muscle 2 & neuromuscular junction, with acj61,3,4.UAS
abdominal ventral longitudinal muscle 3 & neuromuscular junction, with acj61,3,4.UAS
abdominal ventral longitudinal muscle 4 & neuromuscular junction, with acj61,3,4.UAS
aCC neuron & synapse, with Ctet\tetXTNT-LC.UAS
adult abdomen & macrochaeta, with E(spl)m8-HLH1,stop.UAS
adult abdomen & macrochaeta, with E(spl)m8-HLH1.UAS
adult abdomen & macrochaeta, with E(spl)m8-HLHUAS.cGa
adult abdomen & macrochaeta, with E(spl)m8-HLHΔbHIII.UAS
adult abdomen & macrochaeta, with E(spl)m8-HLHΔbHIV.UAS
adult abdomen & macrochaeta, with E(spl)m8-HLHΔbHLH.UAS
adult abdomen & macrochaeta, with grpEP587
adult abdomen & macrochaeta, with MESR4EP386
adult abdomen & macrochaeta, with MESR4EP988
adult abdomen & microchaeta, with bchsEP2299
adult abdomen & microchaeta, with Kr-h1EP2289
adult abdomen & trichogen cell, with aopEP598
adult abdominal sensillum & trichogen cell, with fafEP381
adult head & macrochaeta, with E(spl)m8-HLH1.UAS
adult head & macrochaeta, with E(spl)m8-HLHP-L.UAS
adult head & macrochaeta, with E(spl)m8-HLHUAS.cGa
adult thorax & chaeta, with sggS9A.UAS
adult thorax & chaeta, with sggS9E.UAS
adult thorax & chaeta, with sggUAS.cBa
adult thorax & mechanosensory sensory organ, with nvyUAS.cWa
adult thorax & microchaeta, with sggUAS.cBa
anterior fascicle & motor neuron, with acj61,3,4.UAS
axon & mechanosensory neuron & adult head, with htlAB42, htlDN.UAS.cMb
axon & mechanosensory neuron & adult head, with htlDN.UAS.cMb
axon & ocellus sensory structure, with EgfrDN.UAS.cBa
axon & ocellus sensory structure, with htlAB42, htlDN.UAS.cMb
axon & ocellus sensory structure, with htlDN.UAS.cMb
bract & leg | ectopic, with spis.UAS
chaeta & mesothoracic tergum | ectopic, with AbiUAS.Tag:Myr(Src64B)
external sensory organ precursor cell & dorsal mesothoracic disc, with BobAUAS.cLa
external sensory organ precursor cell & dorsal mesothoracic disc, with TomUAS.cLa
eye photoreceptor cell & eye disc | posterior, with DlM619S.K620R.H2N.UAS
eye photoreceptor cell & eye disc | posterior, with SerY1248S.F2I.UAS
macrochaeta & abdomen & pupa, with Cele\ced-3UAS.cSa
macrochaeta & abdominal sternite 1, with l(1)scUAS.cHa
macrochaeta & abdominal sternite 2, with l(1)scUAS.cHa
macrochaeta & abdominal sternite 3, with l(1)scUAS.cHa
macrochaeta & abdominal sternite 4, with l(1)scUAS.cHa
macrochaeta & abdominal sternite 5, with l(1)scUAS.cHa
macrochaeta & abdominal sternite 6, with l(1)scUAS.cHa
macrochaeta & adult head, with E(spl)m2-BFMUAS.cLa
macrochaeta & head, with neurUAS.cLa
macrochaeta & head, with neurUAS.L.Tag:MYC
macrochaeta & head & pupa, with Cele\ced-3UAS.cSa
macrochaeta & mesothoracic tergum, with AmunGD9779
macrochaeta & mesothoracic tergum, with AmunUAS.mRFP1
macrochaeta & mesothoracic tergum, with E(spl)m2-BFMUAS.cLa
macrochaeta & mesothoracic tergum, with egrGS9830
macrochaeta & mesothoracic tergum, with rprUAS.cIa
macrochaeta & mesothoracic tergum | ectopic, with AmunGD9779
macrochaeta & mesothoracic tergum | ectopic, with AmunUAS.mRFP1
macrochaeta & mesothoracic tergum | supernumerary, with AmunGD9779
macrochaeta & mesothoracic tergum | supernumerary, with AmunUAS.mRFP1
macrochaeta & scutellum, with egrGS9830
macrochaeta & scutellum, with rprUAS.cIa
macrochaeta & scutum, with esgEP684
macrochaeta & scutum, with esgEP2009
macrochaeta & scutum & pupa, with Cele\ced-3UAS.cSa
macrochaeta & tergum, with rprUAS.cIa
macrochaeta & thorax, with tantUAS.cDa
macrochaeta & thorax | supernumerary, with Dl::SerDl-E.Ser-I.UAS
macrochaeta & thorax | supernumerary, with SerY1248S.F2I.UAS
mesothoracic tarsal segment 1 & bract, with aosUAS.cHa
mesothoracic tarsal segment 1 & bract, with EgfrUAS.cBa
mesothoracic tarsal segment 1 & bract | ectopic, with spis.UAS
mesothoracic tergum & macrochaeta, with chndsRNA.UAS
mesothoracic tergum & macrochaeta, with Hsap\EZR1-280.UAS.GFP
microchaeta & leg, with TomUAS.cLa
microchaeta & scutum, with esgEP684
microchaeta & scutum, with esgEP2009
microchaeta & scutum, with hbsUAS.cDa
microtubule cytoskeleton & axon, with β-SpecdsRNA.UAS
neuron & embryonic abdomen | ectopic, with CycEUAS.cLa
neuron & embryonic thorax, with dapUAS.cLa
neuron & embryonic thorax, with Hsap\CDKN1AUAS.cHa
RP2 neuron & synapse, with Ctet\tetXTNT-LC.UAS
scutellum & microchaeta, with emcEP415
scutum & macrochaeta, with RalaS25N.UAS
scutum & macrochaeta & adult, with E(spl)m8-HLH1,stop.UAS
scutum & macrochaeta & adult, with E(spl)m8-HLH1.UAS
scutum & macrochaeta & adult, with E(spl)m8-HLH+,stop.UAS
scutum & macrochaeta & adult, with E(spl)m8-HLHbHLH.UAS
scutum & macrochaeta & adult, with E(spl)m8-HLHUAS.cGa
scutum & macrochaeta & adult, with E(spl)m8-HLHΔbHIV.UAS
scutum & macrochaeta & adult, with E(spl)m8-HLHΔbHLH.UAS
scutum & macrochaeta & tormogen cell, with RalaS25N.UAS
scutum & macrochaeta & trichogen cell, with RalaS25N.UAS
scutum & microchaeta, with BrdUAS.cLa
scutum & microchaeta, with RalaS25N.UAS
scutum & microchaeta & tormogen cell, with RalaS25N.UAS
scutum & microchaeta & trichogen cell, with RalaS25N.UAS
scutum & microchaeta | medial, with araUAS.cGa
scutum & microchaeta | medial, with caupUAS.cdCa
taste bristle & leg | ectopic, with aosUAS.cHa
taste bristle & leg | ectopic, with EgfrUAS.cBa
taste bristle & leg | ectopic, with spis.UAS
thecogen cell & actin filament & pupa, with HemUAS.Tag:Myr(Src64B)
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
EgfrUAS.cUa, Scer\GAL4sca-537.4 has visible phenotype, enhanceable by pum01688/pum[+]
EgfrUAS.cUa, Scer\GAL4sca-537.4 has visible phenotype, enhanceable by pumMsc/pum[+]
NakUAS.cCa, Scer\GAL4sca-537.4 has visible phenotype, enhanceable by numb[+]/numb1
NOT Enhanced by
Statement
Reference
RalaS25N.cMa.UAS, Scer\GAL4sca-537.4 has visible phenotype, non-enhanceable by DreddB118/Dredd[+]
RalaS25N.cMa.UAS, Scer\GAL4sca-537.4 has visible phenotype, non-enhanceable by Dredd[+]/DreddL23
Suppressed by
Statement
Reference
NOT suppressed by
Statement
Reference
RalaS25N.cMa.UAS, Scer\GAL4sca-537.4 has visible phenotype, non-suppressible by DreddB118/Dredd[+]
RalaS25N.cMa.UAS, Scer\GAL4sca-537.4 has visible phenotype, non-suppressible by Dredd[+]/DreddL23
Scer\GAL4sca-537.4, dbrEP456 has visible phenotype, non-suppressible by H[+]/HE21
Scer\GAL4sca-537.4, tweEP613 has visible phenotype, non-suppressible by H[+]/HE21
Scer\GAL4sca-537.4, aopEP598 has visible phenotype, non-suppressible by H[+]/HE21
Scer\GAL4sca-537.4, stgEP1213 has visible phenotype, non-suppressible by H[+]/HE21
Scer\GAL4sca-537.4, qsmEP2356 has visible phenotype, non-suppressible by H[+]/HE21
Scer\GAL4sca-537.4, pblEP3415 has visible phenotype, non-suppressible by H[+]/HE21
BxEP1383, Scer\GAL4sca-537.4 has visible phenotype, non-suppressible by H[+]/HE21
Scer\GAL4sca-537.4, wdbEP3559 has visible phenotype, non-suppressible by H[+]/HE21
Scer\GAL4sca-537.4, sdEP1435 has visible phenotype, non-suppressible by H[+]/HE21
RalaS25N.UAS, Scer\GAL4sca-537.4 has visible phenotype, non-suppressible by rl9
Enhancer of
Statement
Reference
NOT Enhancer of
Suppressor of
Statement
Reference
NOT Suppressor of
Phenotype Manifest In
Enhanced by
Statement
Reference
EgfrUAS.cUa, Scer\GAL4sca-537.4 has macrochaeta | ectopic phenotype, enhanceable by pumMsc/pum[+]
Scer\GAL4sca-537.4, htlDN.UAS.cMb has axon & mechanosensory neuron & adult head phenotype, enhanceable by Egfr[+]/Egfrunspecified
NakUAS.cCa, Scer\GAL4sca-537.4 has wing sensillum phenotype, enhanceable by numb[+]/numb1
NakUAS.cCa, Scer\GAL4sca-537.4 has head sensillum phenotype, enhanceable by numb[+]/numb1
NOT Enhanced by
Statement
Reference
Scer\GAL4sca-537.4, htlDN.UAS.cMb has axon & ocellus sensory structure phenotype, non-enhanceable by EgfrE3/Egfr[+]
Suppressed by
Statement
Reference
Scer\GAL4sca-537.4, nvyUAS.cWa has adult thorax & mechanosensory sensory organ phenotype, suppressible by sensUAS.cNa
Scer\GAL4sca-537.4, htlDN.UAS.cMb has axon & ocellus sensory structure phenotype, suppressible by Egfr[+]/Egfrunspecified
RalaS25N.UAS, Scer\GAL4sca-537.4 has scutum & macrochaeta phenotype, suppressible by hep[+]/hepr75
RalaS25N.UAS, Scer\GAL4sca-537.4 has scutum & macrochaeta phenotype, suppressible by hep[+]/hep1
RalaS25N.UAS, Scer\GAL4sca-537.4 has scutum & macrochaeta phenotype, suppressible by bskflp147E/bsk[+]
RalaS25N.UAS, Scer\GAL4sca-537.4 has scutum & macrochaeta phenotype, suppressible by bsk2/bsk[+]
RalaS25N.UAS, Scer\GAL4sca-537.4 has scutum & macrochaeta phenotype, suppressible by bsk1/bsk[+]
NOT suppressed by
Statement
Reference
Scer\GAL4sca-537.4, htlDN.UAS.cMb has axon & mechanosensory neuron & adult head phenotype, non-suppressible by EgfrE3/Egfr[+]
Enhancer of
Statement
Reference
NOT Enhancer of
Statement
Reference
Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference
edΔECD.UAS/Scer\GAL4sca-537.4 is a non-suppressor of microchaeta | heat sensitive phenotype of NECN.hs
edΔECD.UAS/Scer\GAL4sca-537.4 is a non-suppressor of microchaeta | heat sensitive phenotype of Nicd.hs
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Fails to rescue
Comments
Neuroblast-specific expression of α-AdaptinScer\UAS.T:Avic\GFP via Scer\GAL4insc-Mz1407 completely rescues the brain tumor phenotype of α-AdaptinSH0460.
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
GAL4sca-537.4
GAL4sca-H
Scer\GAL4sca-537.4
Name Synonyms
Secondary FlyBase IDs
  • FBal0040488
  • FBal0061869
References (169)