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General Information
Symbol
Scer\GAL4dpp.blk1
Species
S. cerevisiae
Name
FlyBase ID
FBal0040480
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
dpp-GAL4, dppGAL4, dppblk-Gal4, dppblink-GAL4, blk-GAL4, dppdisk-Gal4, decapentaplegic-GAL4, dppDISC-GAl4, DppblkGal4, dpp-blink.Gal4
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Expression of a GAL4 driver is controlled by the 4kb BamHI dpp blk enhancer within the 106-110 region.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Expression Data
Reporter Expression
No Assay Recorded
Stage
Tissue/Position (including subcellular localization)
Reference
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Drives expression at the anterior/posterior compartment boundary of imaginal discs, and at the morphogenetic furrow of the eye disc.

Scer\GAL4dpp.blk1 drives expression in neuroblasts positioned along the distal edge and in cells of the proximal part of the inner proliferation zone in the larval optic anlage.

Scer\GAL4dpp.blk1 drives expression in a subset of adult hemocytes; expressing cells are most abundant in the thorax and around the dorsal vessel in the abdomen, with few expressing cells in other abdomenal regions or in the legs. Scer\GAL4dpp.blk1 also drives expression in adult pericardial nephrocytes, and in salivary glands.

Scer\GAL4dpp.blk1 expression is not seen in the posterior compartment and a sharp boundary is created at the A/P border, whereas it declines gradually in the anterior compartment with stronger expression on the dorsal side than on the ventral side.

Expression in wandering third instar larvae is observed in imaginal discs, in the salivary glands, and in the midgut.

Expression is observed at the morphogenetic furrow.

Expression is observed in both the male and female genital discs, and is complementary to that of wg. Expression is excluded from the repressed male primordium in the female genital disc.

Late third instar expression is observed in a stripe of cells posterior to the dorsocentral sensory mother cells in the wing disc.

 
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

antennal disc & eye | ectopic, with eyUAS.cHa

antennal segment & eye | ectopic, with eyaUAS.cBa

chordotonal organ & wing | ectopic, with atoUAS.cJa

chordotonal organ & wing | ectopic, with Mmus\Atoh1UAS.cQa

dorsal mesothoracic disc & actin filament | ectopic, with PvrUAS.cRa

eye photoreceptor cell & dorsal mesothoracic disc | ectopic, with eyUAS.cHa

eye photoreceptor cell & ventral thoracic disc | ectopic, with eyUAS.cHa

eye photoreceptor cell | ectopic & antennal disc, with eyUAS.cHa

haltere & macrochaeta, with scUAS.cHa

haltere & ommatidium | ectopic, with eyUAS.cHa

leg & chaeta, with sensUAS.cNa

leg & eye | ectopic, with eyUAS.cHa

leg & eye | ectopic, with toyUAS.cCa

leg & ommatidium | ectopic, with eyaUAS.cBa

macrochaeta & wing | ectopic, with atoUAS.cJa

macrochaeta & wing | ectopic, with Mmus\Atoh1UAS.cQa

macrochaeta & wing | ectopic, with Mmus\Neurog1bato.UAS

macrochaeta & wing | ectopic, with Mmus\Neurog1H2ato.UAS

macrochaeta & wing | ectopic, with Mmus\Neurog1UAS.cQa

proboscis & ommatidium | ectopic, with eyUAS.cHa

scutellum & macrochaeta, with dppUAS.cSa

scutum & chaeta, with sensUAS.cNa

scutum & macrochaeta, with sktlUAS.cHa

sensory mother cell | ectopic & dorsal mesothoracic disc, with amosUAS.cGa

ventral thoracic disc & eye | ectopic, with eyUAS.cHa

wing & chaeta, with sensUAS.cNa

wing & eye | ectopic, with toyUAS.cCa

wing & macrochaeta, with pbUAS.A

wing & macrochaeta, with scUAS.cHa

wing & macrochaeta, with SerUAS.cSa

wing & macrochaeta, with sktlUAS.cHa

wing & ommatidium | ectopic, with eyaUAS.cBa

wing vein L3 & chaeta | ectopic, with phylUAS.cPa

wing vein L3 & sensory neuron

Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

Scer\GAL4dpp.blk1, tkvQ253D.UAS.cNb has visible phenotype, enhanceable by nmoP1/nmo[+]

NOT Enhanced by
Suppressed by
Statement
Reference

MitfUAS.cZa, Scer\GAL4dpp.blk1 has visible | adult stage phenotype, suppressible by Vha55[+]/Vha5516

MoedsRNA.327-775.UAS, Scer\GAL4dpp.blk1, pucE69/puc[+] has visible phenotype, suppressible by Rho172R/Rho1[+]

Scer\GAL4dpp.blk1, tshUAS.cGa has visible phenotype, suppressible by wgl-12/wg[+]

Scer\GAL4dpp.blk1, tshUAS.cGa has visible phenotype, suppressible by hthdtl-S142204/hth[+]

NOT suppressed by
Statement
Reference

HIV-1\VpuUAS.cLa, Scer\GAL4dpp.blk1 has visible phenotype, non-suppressible by msn[+]/msn102

HIV-1\VpuUAS.cLa, Scer\GAL4dpp.blk1 has visible phenotype, non-suppressible by msn[+]/msn06946

HIV-1\VpuUAS.cLa, Scer\GAL4dpp.blk1 has visible phenotype, non-suppressible by Rac1J11/Rac1[+]

HIV-1\VpuUAS.cLa, Scer\GAL4dpp.blk1 has visible phenotype, non-suppressible by Rac1J11/Rac2Δ/Rac2[+]/Rac1[+]

Enhancer of
Statement
Reference

Scer\GAL4dpp.blk1, coro[+], coroex11 is an enhancer of visible phenotype of tkvQ253D.UAS.cNb

coroex6, Scer\GAL4dpp.blk1, coro[+] is an enhancer of visible phenotype of tkvQ253D.UAS.cNb

NOT Enhancer of
Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

PvrDN.UASp, Scer\GAL4dpp.blk1 has male terminalia phenotype, enhanceable by Pvf1[-]

Mmus\Neurog1UAS.cQa, Scer\GAL4dpp.blk1 has macrochaeta & wing | ectopic phenotype, enhanceable by Df(1)N-8/+

NOT Enhanced by
Statement
Reference

Mmus\Neurog1UAS.cQa, Scer\GAL4dpp.blk1 has macrochaeta & wing | ectopic phenotype, non-enhanceable by E(spl)m8-HLHunspecified

Mmus\Neurog1UAS.cQa, Scer\GAL4dpp.blk1 has macrochaeta & wing | ectopic phenotype, non-enhanceable by Mmus\Neurog2UAS.cQa

Mmus\Neurog1UAS.cQa, Scer\GAL4dpp.blk1 has macrochaeta & wing | ectopic phenotype, non-enhanceable by Mmus\Neurod4UAS.cQa

Suppressed by
Statement
Reference

MitfUAS.cZa, Scer\GAL4dpp.blk1 has wing | adult stage phenotype, suppressible by Vha14-1[+]/Vha14-1EY12998

MitfUAS.cZa, Scer\GAL4dpp.blk1 has wing | adult stage phenotype, suppressible by Vha13[+]/Vha13CA07644

MitfUAS.cZa, Scer\GAL4dpp.blk1 has wing | adult stage phenotype, suppressible by Vha55[+]/Vha5516

MitfUAS.cZa, Scer\GAL4dpp.blk1 has wing | adult stage phenotype, suppressible | partially by Vha68-2[+]/Vha68-2R6

HIV-1\VpuUAS.cLa, Scer\GAL4dpp.blk1 has wing phenotype, suppressible | partially by bsk1/bsk[+]

Scer\GAL4dpp.blk1, eyaWT.UAS has eye | ectopic phenotype, suppressible by Abl4/Abl[+]

Scer\GAL4dpp.blk1, eyaWT.UAS has eye | ectopic phenotype, suppressible by Abl04674/Abl[+]

Mmus\Neurog1bato.UAS, Scer\GAL4dpp.blk1 has macrochaeta & wing | ectopic phenotype, suppressible | partially by sensE1/sens[+]

Mmus\Neurog1UAS.cQa, Scer\GAL4dpp.blk1 has macrochaeta & wing | ectopic phenotype, suppressible by E(spl)m8-HLHUAS.cTa

Mmus\Neurog1UAS.cQa, Scer\GAL4dpp.blk1 has macrochaeta & wing | ectopic phenotype, suppressible by E(spl)mδ-HLHUAS.cdCa

Mmus\Neurog1UAS.cQa, Scer\GAL4dpp.blk1 has macrochaeta & wing | ectopic phenotype, suppressible by Nintra.GS.UAS

Scer\GAL4dpp.blk1, tshUAS.cGa has eye phenotype, suppressible by hthdtl-S142204/hth[+]

Scer\GAL4dpp.blk1, tshUAS.cGa has eye phenotype, suppressible by wgl-12/wg[+]

Scer\GAL4dpp.blk1, eyaS-A.UAS has eye | ectopic phenotype, suppressible | partially by rl[+]/rlS-135

Scer\GAL4dpp.blk1, toyUAS.cCa has eye | ectopic phenotype, suppressible by ey2

NOT suppressed by
Statement
Reference

HIV-1\VpuUAS.cLa, Scer\GAL4dpp.blk1 has wing phenotype, non-suppressible by msn[+]/msn102

HIV-1\VpuUAS.cLa, Scer\GAL4dpp.blk1 has wing phenotype, non-suppressible by msn[+]/msn06946

HIV-1\VpuUAS.cLa, Scer\GAL4dpp.blk1 has wing phenotype, non-suppressible by Rac1J11/Rac1[+]

HIV-1\VpuUAS.cLa, Scer\GAL4dpp.blk1 has wing phenotype, non-suppressible by Rac1J11/Rac2Δ/Rac2[+]/Rac1[+]

Gp150UAS.cLa, Scer\GAL4dpp.blk1 has wing margin phenotype, non-suppressible by scaBP2

Scer\GAL4dpp.blk1, eyaUAS.cHa has eye | ectopic phenotype, non-suppressible by bsk1

Enhancer of
Statement
Reference

talUAS.cPa/Scer\GAL4dpp.blk1 is an enhancer of wing phen