FB2025_01 , released February 20, 2025
Allele: Scer\GAL4ptc-559.1
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General Information
Symbol
Scer\GAL4ptc-559.1
Species
S. cerevisiae
Name
FlyBase ID
FBal0040487
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
ptc-GAL4, ptcGal4, patched-gal4, ptc.Gal4, GAL4559.1, ptcgal4, ptc559.1-Gal4, ptc::Gal4, P{GawB}559.1, 559.1
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description
Allele components
Component
Use(s)
Inserted element
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
No Assay Recorded
Stage
Tissue/Position (including subcellular localization)
Reference
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Drives embryonic expresion in a segment polarity expression pattern, and larval expression anterior to the A/P compartment boundary of the wing disc.

ScerGAL4ptc-559.1 drives expression at the boundary of the anterior, or 'H1', and posterior, or 'H2', regions of the hindgut imaginal ring.

ScerGAL4ptc-559.1 drives expression in octopaminergic neurons in the abdominal ganglion.

ScerGAL4ptc-559.1 drives expression in anterior cells immediately adjacent to the A/P compartment bounary of the wing disc.

Adult expression is observed in the mushroom body and in the posterior tip of the thoracic ganglion.

In embryonic brain, higher levels in region surrounding foregut (a region of hh expression). Expressed in embryonic brain in a segmental pattern complementary to that of hh.

ScerGAL4ptc-559.1 drives expression in the at the anterior/posterior compartment boundary of the wing disc.

In wing disc, expressed in a stripe of cells along the anterior-posterior border.

 
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

cell & larval salivary gland | somatic clone, with miGD11624

disc epithelium proper & dorsal mesothoracic disc, with Rho1UAS.cMa

dorsal mesothoracic disc & actin filament, with PvrRNAi.UAS.cRa

embryonic leading edge cell & actin filament, with RacGAP84CUAS.cRa

embryonic leading edge cell & actin filament, with wg-C.UAS

filamentous actin & embryonic/first instar larval cuticle | ectopic, with ovoUAS.cPa

leg & adult cuticle, with oddUAS.cHa

leg & adult cuticle, with sobUAS.cGa

macrochaeta & mesothoracic tergum, with AmunGD9779

macrochaeta & mesothoracic tergum, with AmunUAS.mRFP1

macrochaeta & mesothoracic tergum | ectopic, with AmunGD9779

macrochaeta & mesothoracic tergum | supernumerary, with AmunGD9779

macrochaeta & postnotum, with Ncdc10.UAS.Tag:MYC

macrochaeta & scutellum, with dshUAS.cAa

macrochaeta & wing, with SerUAS.cSa

microchaeta & scutellum, with dshUAS.cAa

microchaeta & tarsal segment 5, with pxbUAS.cIa

nucleus & cell & larval salivary gland | somatic clone, with miGD11624

peripodial epithelium & dorsal mesothoracic disc, with linUAS.cHa

proneural cluster & dorsal mesothoracic disc, with NECNΔ10-12.UAS

scutellum & microchaeta, with l(1)scUAS.cHa

sensory mother cell & dorsal mesothoracic disc, with atoUAS.cJa

sensory mother cell & dorsal mesothoracic disc, with scUAS.cCa

tarsal segment & joint, with Su(dx)UAS.cCa

trichome & adult abdomen, with stanUAS.cUa

wing & microchaeta, with fzUAS.cAa

wing & microchaeta, with NUAS.cSa

wing hair & 1st posterior cell, with dshUAS.cAa

wing hair & 1st posterior cell, with fzUAS.cAa

wing hair & 1st posterior cell, with pkUAS.cGa

wing hair & 1st posterior cell, with stanUAS.cUa

zonula adherens & disc epithelium proper, with CskRNAi.UAS

Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, enhanceable by E(Pc)[+]/E(Pc)w3

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, enhanceable by E(Pc)D4/E(Pc)[+]

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, enhanceable by Mi-2[+]/Mi-2j3D4

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, enhanceable by Su(z)2[+]/Su(z)23-1

Scer\GAL4ptc-559.1, smoRNAi.UAS.WIZ has visible phenotype, enhanceable by hh[+]/hh10

Scer\GAL4ptc-559.1, trcT453A.UAS.L has visible phenotype, enhanceable by matse235/mats[+]

Scer\GAL4ptc-559.1, trcT453A.UAS.L has visible phenotype, enhanceable by matse03077/mats[+]

Scer\GAL4ptc-559.1, trcT453A.UAS.L has visible phenotype, enhanceable by wts[+]/wts3-17

NOT Enhanced by
Statement
Reference

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, non-enhanceable by esc1/esc[+]

Scer\GAL4ptc-559.1, trcT453A.UAS.L has visible phenotype, non-enhanceable by matsPBrv/mats[+]

Suppressed by
Statement
Reference

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by Su(z)21/Su(z)2[+]

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by Su(z)21.a1/Su(z)2[+]

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by Su(z)21.b7/Su(z)2[+]

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by Su(z)2k06344/Su(z)2[+]

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by Asx[+]/Asx1

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by eff[+]/effmer4

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by e(Pc)84DET66.1/e(Pc)84DE[+]

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by esc21/esc[+]

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by His2Av[+]/His2Av810

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by His2Av[+]/His2Av05146

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by kisBG01657/kis[+]

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by Pc3/Pc[+]

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by Pc[+]/Pcf01890

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by pho[+]/pho1

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by ScmD1/Scm[+]

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by Su(z)123/Su(z)12[+]

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by tara1/tara[+]

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by tou2/tou[+]

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by brm[+]/brm2

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by trx[+]/trxKG08639

Scer\GAL4ptc-559.1, smoRNAi.UAS.WIZ has visible phenotype, suppressible by swmF4/swm[+]

Scer\GAL4ptc-559.1, smoRNAi.UAS.WIZ has visible phenotype, suppressible by swmF14/swm[+]

Scer\GAL4ptc-559.1, smoRNAi.UAS.WIZ has visible phenotype, suppressible by swmF11/swm[+]

Scer\GAL4ptc-559.1, smoRNAi.UAS.WIZ has visible phenotype, suppressible by ptc[+]/ptc10

Atg1UAS.cCa, Scer\GAL4ptc-559.1 has visible phenotype, suppressible by EcR[+]/EcR225

NOT suppressed by
Statement
Reference

E2f1RNAi.UAS.cJa, Scer\GAL4ptc-559.1 has visible phenotype, non-suppressible by esc1/esc[+]

Scer\GAL4ptc-559.1, smoRNAi.UAS.WIZ has visible phenotype, non-suppressible by swmF15/swm[+]

Enhancer of
Statement
Reference
NOT Enhancer of
Statement
Reference
Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference

Scer\GAL4ptc-559.1/RokCAT-KG.UAS is a non-suppressor of visible phenotype of mwh6/mwh1

Scer\GAL4ptc-559.1/tsgUAS.cYa is a non-suppressor of visible phenotype of cv1

Phenotype Manifest In
Enhanced by
Statement
Reference

CskGD9345, Scer\GAL4ptc-559.1 has wing disc phenotype, enhanceable by dia[+]/dia5

CskGD9345, Scer\GAL4ptc-559.1 has wing disc phenotype, enhanceable by shg[+]/shg2

CskGD9345, Scer\GAL4ptc-559.1 has wing disc phenotype, enhanceable by shg[+]/shgR6

Scer\GAL4ptc-559.1, Sin3AKK100700 has wing disc phenotype, enhanceable by pucE69/puc[+]

Mmus\Dlk1SM.UAS, Scer\GAL4ptc-559.1 has wing phenotype, enhanceable by N[+]/N55e11

Mmus\Dlk1M.UAS, Scer\GAL4ptc-559.1 has wing phenotype, enhanceable by N[+]/N55e11

CskRNAi.UAS, Scer\GAL4ptc-559.1 has zonula adherens & disc epithelium proper phenotype, enhanceable by pucE69/puc[+]

NOT Enhanced by
Statement
Reference

Scer\GAL4ptc-559.1, Sin3AKK100700 has wing disc phenotype, non-enhanceable by pydunspecified/pyd[+]

Mmus\Dlk1SM.UAS, Scer\GAL4ptc-559.1 has wing cell phenotype, non-enhanceable by N[+]/N55e11

Suppressed by
Statement
Reference

CskGD9345, Scer\GAL4ptc-559.1 has wing disc phenotype, suppressible by tsr[+]/tsrN96A

CskGD9345, Scer\GAL4ptc-559.1 has wing disc phenotype, suppressible by zip[+]/zip1

CskGD9345, Scer\GAL4ptc-559.1 has wing disc phenotype, suppressible by zip2/zip[+]

CskGD9345, Scer\GAL4ptc-559.1 has wing disc phenotype, suppressible by ena23/ena[+]

CskGD9345, Scer\GAL4ptc-559.1 has wing disc phenotype, suppressible by ena[+]/ena210

CskGD9345, Scer\GAL4ptc-559.1 has wing disc phenotype, suppressible by tumDH15/tum[+]

CskGD9345, Scer\GAL4ptc-559.1 has wing disc phenotype, suppressible by bsk1/bsk[+]

CskGD9345, Scer\GAL4ptc-559.1 has wing disc phenotype, suppressible by bsk2/bsk[+]

CskGD9345, Scer\GAL4ptc-559.1 has wing disc phenotype, suppressible by Arpc1[+]/Arpc1Q25st

CskGD9345, Scer\GAL4ptc-559.1 has wing disc phenotype, suppressible by Arpc1Q25sd/Arpc1[+]

Rho1UAS.cMa, Scer\GAL4ptc-559.1 has wing disc phenotype, suppressible by ena23/ena[+]

Scer\GAL4ptc-559.1, hepUAS.cUa has wing disc phenotype, suppressible by ena23/ena[+]

Scer\GAL4ptc-559.1, hepUAS.cUa has wing disc phenotype, suppressible by ena[+]/ena210

Scer\GAL4ptc-559.1, Sin3AKK100700 has wing disc phenotype, suppressible by bsk2/bsk[+]

Scer\GAL4ptc-559.1, Sin3AKK100700 has wing disc phenotype, suppressible by shg[+]/shgR69

Scer\GAL4ptc-559.1, smoRNAi.UAS.WIZ has wing vein phenotype, suppressible by swmF4/swm[+]

Scer\GAL4ptc-559.1, smoRNAi.UAS.WIZ has wing vein phenotype, suppressible by swmF14/swm[+]

Scer\GAL4ptc-559.1, smoRNAi.UAS.WIZ has wing vein phenotype, suppressible by swmF11/swm[+]

Scer\GAL4ptc-559.1, smoRNAi.UAS.WIZ has wing vein phenotype, suppressible by ptc[+]/ptc10

Atg1UAS.cCa, Scer\GAL4ptc-559.1 has wing hair phenotype, suppressible by EcR[+]/EcR225

CskRNAi.UAS, Scer\GAL4ptc-559.1 has zonula adherens & disc epithelium proper phenotype, suppressible by pucUAS.cMa

CskRNAi.UAS, Scer\GAL4ptc-559.1 has zonula adherens & disc epithelium proper phenotype, suppressible by Rho172O/Rho1[+]

CskRNAi.UAS, Scer\GAL4ptc-559.1 has zonula adherens & disc epithelium proper phenotype, suppressible by shg[+]/shgR69

CskRNAi.UAS, Scer\GAL4ptc-559.1 has zonula adherens & disc epithelium proper phenotype, suppressible by p120ctn[+]/p120ctn308

Scer\GAL4ptc-559.1, fzUAS.cSa has trichome & adult abdomen phenotype, suppressible by stanE59/stan3

NECNΔ10-12.UAS, Scer\GAL4ptc-559.1 has proneural cluster & dorsal mesothoracic disc phenotype, suppressible | somatic clone by sggM11

NOT suppressed by
Statement
Reference

Scer\GAL4ptc-559.1, Sin3AKK100700 has wing disc phenotype, non-suppressible by pydunspecified/pyd[+]

Scer\GAL4ptc-559.1, smoRNAi.UAS.WIZ has wing vein phenotype, non-suppressible by swmF15/swm[+]

Enhancer of
Statement
Reference
NOT Enhancer of
Suppressor of
Statement
Reference

Scer\GAL4ptc-559.1/pkUAS.cGa is a suppressor of wing hair & 1st posterior cell phenotype of in1

Scer\GAL4ptc-559.1/ciUAS.Tag:HA is a suppressor of wing phenotype of fu1

NOT Suppressor of
Statement
Reference

Scer\GAL4ptc-559.1/Pex2UAS.cCa is a non-suppressor of spermatid phenotype of Pex107

Scer\GAL4ptc-559.1/Pex2UAS.cCa is a non-suppressor of testis phenotype of Pex107

Scer\GAL4ptc-559.1/Pex2UAS.cCa is a non-suppressor of testis phenotype of Pex1010

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Rescues
Comments
Images (0)
Mutant
Wild-type
Stocks (5)
Notes on Origin
Discoverer
Comments
Comments

GAL4 expression is driven by the ptc promoter in this enhancer trap element.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (684)