Allele Ecol\lacZ^esg-A507.2M2

General Information
Symbol	Ecol\lacZ^esg-A507.2M2	Species	E. coli
Name		FlyBase ID	FBal0040735
Feature type	allele	Associated gene	Ecol\lacZ
Also Known As	mgm1

Allele class
Mutagen	P-element activity
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity (Bellen et al., 1989, Staab et al., 1996)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference P-element insertion at cytological location 35D-35E. (Bellen et al., 1989)
Caused by insertion	P{lArB}A507.2M2 (Bellen et al., 1989, Staab et al., 1996, Bellen, 1998.8.10, Heller and Steinmann-Zwicky, 1998, Roote, 1996.9.24, Heller and Steinmann-Zwicky, 1998, Arbouzova and Zeidler, 2006, Wawersik et al., 2005, Streit et al., 2002)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 2 )
Bloomington	11033 CyO, P{lArB}A507.2M2, chif^A507/b¹ Adh^* cn^* l(2)^; ry⁵⁰⁶
Kyoto	108984 CyO, P{lArB}A507.2M2, chif^A507/b¹ Adh^* cn^* l(2)^; ry⁵⁰⁶
Notes on Origin
Discoverer

Comments
	Expressed specifically in male germ cells and not in proliferating germ cells. (Staab et al., 1996)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	Ecol\lacZ^A507.2M2 Ecol\lacZ^esg-A507.2M2 lacZ^A507.2M2 mgm1 (Streit et al., 1999, Heller and Steinmann-Zwicky, 1998, Heller and Steinmann-Zwicky, 1998, Lin, 1997, Staab et al., 1996) mgm-1 (Arbouzova and Zeidler, 2006)
Name Synonym	male germline-marker 1 (Staab et al., 1996) male germline marker 1 (Casper and Van Doren, 2006)
Secondary FlyBase IDs

References ( 13 )
Research paper	Wawersik et al., 2005, Nature 436(7050): 563--567 Somatic control of germline sexual development is mediated by the JAK/STAT pathway. [FBrf0188143] Streit et al., 2002, Int. J. Dev. Biol. 46(1 Spec No): 159--166 mgm1, the earliest sex-specific germline marker in Drosophila, reflects expression of the gene esg in male stem cells. [FBrf0147086] Janzer and Steinmann-Zwicky, 2001, Mech. Dev. 100(1): 3--13 Cell-autonomous and somatic signals control sex-specific gene expression in XY germ cells of Drosophila. [FBrf0132399] Heller and Steinmann-Zwicky, 1998, Mech. Dev. 73(2): 203--209 In Drosophila, female gonadal cells repress male-specific gene expression in XX germ cells. [FBrf0102745] Heller and Steinmann-Zwicky, 1998, Mech. Dev. 72(1,2): 169--173 No premature gene expression in germ cells of embryos deriving from nos females. [FBrf0102183] Staab et al., 1996, Development 122(12): 4065--4071 Somatic sex-determining signals act on XX germ cells in Drosophila embryos. [FBrf0091303] Bellen et al., 1989, Genes Dev. 3: 1288--1300 P-element-mediated enhancer detection: a versatile method to study development in Drosophila. [FBrf0049801]
Review	Arbouzova and Zeidler, 2006, Development 133(14): 2605--2616 JAK/STAT signalling in Drosophila: insights into conserved regulatory and cellular functions. [FBrf0193685] Casper and Van Doren, 2006, Development 133(15): 2783--2791 The control of sexual identity in the Drosophila germline. [FBrf0193937] Lin, 1997, A. Rev. Genet. 31: 455--491 The tao of stem cells in the germline. [FBrf0100666]
Personal communication to FlyBase	Bellen, 1998.8.10, Patterns of insertions of lacZ reporter constructs. Patterns of insertions of lacZ reporter constructs. [FBrf0103137] Roote, 1996.9.24, A507 mutant for chiffon? A507 mutant for chiffon? [FBrf0089995]
Abstract	Streit et al., 1999, Europ. Dros. Res. Conf. 16: 246 Early sex-specific gene expression in germ cells. [FBrf0110883]

Allele Ecol\lacZesg-A507.2M2

Allele Ecol\lacZ^esg-A507.2M2