Allele Scer\GAL4^T80

General Information
Symbol	Scer\GAL4^T80	Species	S. cerevisiae
Name		FlyBase ID	FBal0042563
Feature type	allele	Associated gene	Scer\GAL4
Also Known As	T80

Allele class
Mutagen	P-element activity
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity (Wilder and Perrimon, 1995, Rorth, 1996, Brand, 1997.6.30)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{GawB}T80 (Wilder and Perrimon, 1995, Denholm et al., 2005, Yoshida et al., 2004, Hollmann et al., 2002, Ward et al., 2001, Beller et al., 2002, Tal et al., 2002, Billuart et al., 2001, Takaesu et al., 2005, Speck et al., 2003, Bardot et al., 2002, Hrdlicka et al., 2002, Negeri et al., 2002, Donaldson et al., 2004, Fortier and Belote, 2000, Chen et al., 2004, Ahmed et al., 2003, Ben-Yaacov et al., 2001, Turnage et al., 2000, Ye and Fortini, 1999, Cullen and McCall, 2004, Hernandez et al., 2005, Nagaraj et al., 1999, Brand, 1997.6.30, Marquez et al., 2001, Fossgreen et al., 1998, LaJeunesse et al., 1998, Schnepp et al., 1996, Rorth, 1996, Yaich et al., 1998, Beller et al., 2002, Gorczyca et al., 2007, Lu et al., 2006, Hull-Thompson et al., 2009, Hyun et al., 2006, Eggert et al., 2004, Maxwell et al., 2008, Blanke and Jackle, 2006, Casso et al., 2012, Gutiérrez et al., 2012, Casso et al., 2008, Jung et al., 2007, Li et al., 2007, Morris et al., 2006, Vicente-Crespo et al., 2008, Tang et al., 2008, Schulze et al., 2009, Fraichard et al., 2010, Wang and Ward, 2010, Loveall and Deitcher, 2010, Winther et al., 2006, Neto-Silva et al., 2010, Rendina et al., 2010, Schirling et al., 2010, Hughes et al., 2010, Muyrers-Chen et al., 2004, Lloyd et al., 2012, Takaesu et al., 2012, Qi et al., 2006, Hyun and Hashimoto, 2011)
Cytology
Phenotypic Data
Phenotypic Class
	developmental rate defective \| larval stage, with kay^{dsRNA.Scer\UAS} (Hyun et al., 2006) eye color defective, with w^{dsRNA.Scer\UAS.cNa} (Negeri et al., 2002) fertile, with LIMK1^{D522A.Scer\UAS} (Chen et al., 2004) lethal, with bab1^Scer\UAS.cGa (Bardot et al., 2002) lethal, with bab2^4.Scer\UAS (Bardot et al., 2002) lethal, with BacA\p35^Scer\UAS.cHa (Morris et al., 2006) lethal, with Baldspot^{dsRNA.Scer\UAS.cJa} (Jung et al., 2007) lethal, with CycE^Scer\UAS.cLa (Morris et al., 2006) lethal, with Dad^Scer\UAS.cTa (Marquez et al., 2001) lethal, with dap^{Scer\UAS.cdNa} (Morris et al., 2006) lethal, with E2f^Scer\UAS.cNa (Morris et al., 2006) lethal, with EP115^EP115 (Rorth, 1996) lethal, with Hsap\CDKN1A^Scer\UAS.cHa (Morris et al., 2006) lethal, with Hsap\MLL::Hsap\AFF1^Scer\UAS.cMa (Muyrers-Chen et al., 2004) lethal, with Hsap\MLL::Hsap\MLLT3^{Scer\UAS.C.T:Zzzz\FLAG} (Muyrers-Chen et al., 2004) lethal, with kay^{dsRNA.Scer\UAS} (Hyun et al., 2006) lethal, with LamC^{ΔN.Scer\UAS.cSa} (Schulze et al., 2009) lethal, with peb^EP55 (Rorth, 1996) lethal, with pzg^Scer\UAS.cEa (Eggert et al., 2004) lethal, with RhoGAP93B^{dsRNA.Scer\UAS} (Billuart et al., 2001) lethal, with rpr^Scer\UAS.cZa (Morris et al., 2006) lethal, with tra2^{Scer\UAS.T:Hsap\MYC} (Qi et al., 2006) lethal \| embryonic stage, with Bx42^{dsRNA.Scer\UAS} (Negeri et al., 2002) lethal \| heat sensitive, with Tip60^{Scer\UAS.Scer\UAS.cSa} (Schirling et al., 2010) lethal \| larval stage, with Dref^{dsRNA.h-h.Scer\UAS} (Yoshida et al., 2004) lethal \| larval stage, with GEFmeso^Scer\UAS.cBa (Blanke and Jackle, 2006) lethal \| larval stage, with sktl^Scer\UAS.cHa (Hassan et al., 1998) lethal \| pharate adult stage, with rk^GD14383 (Loveall and Deitcher, 2010) lethal \| pupal stage, with Dref^{dsRNA.h-h.Scer\UAS} (Yoshida et al., 2004) mitotic cell cycle defective, with kay^{dsRNA.Scer\UAS} (Hyun et al., 2006) partially lethal - majority die, with LamC^{W557S.Scer\UAS} (Schulze et al., 2009) partially lethal - majority die, with su(s)^Scer\UAS.cTa (Turnage et al., 2000) partially lethal - majority die, with tum^{dsRNA.Scer\UAS.cBa} (Billuart et al., 2001) partially lethal - majority live, with Mad^1.Scer\UAS (Takaesu et al., 2005) viable, with f^{dsRNA.Scer\UAS.fIR} (Maxwell et al., 2008) viable, with Hsap\MLL^{Scer\UAS.C.T:Zzzz\FLAG} (Muyrers-Chen et al., 2004) viable, with Ide^{dsRNA.Scer\UAS} (Hyun and Hashimoto, 2011) viable, with LamC^hs.PSb (Schulze et al., 2009) viable, with LamC^{K493W.Scer\UAS} (Schulze et al., 2009) viable, with LamC^{L567P.Scer\UAS} (Schulze et al., 2009) viable, with LamC^{N210K.Scer\UAS} (Schulze et al., 2009) viable, with LamC^{R401K.Scer\UAS.cSa} (Schulze et al., 2009) viable, with LamC^ΔC.Scer\UAS (Schulze et al., 2009) viable, with LIMK1^{D522A.Scer\UAS} (Chen et al., 2004) viable, with Tk^{dsRNA.Scer\UAS.cWa} (Winther et al., 2006) viable, with tra2^{dsRNA.Scer\UAS} (Maxwell et al., 2008) visible, with Bap170^{dsRNA.Scer\UAS.cRa} (Rendina et al., 2010) visible, with cv-c^{dsRNA.Scer\UAS} (Billuart et al., 2001) visible, with ed^Ext.Scer\UAS (Ahmed et al., 2003) visible, with Hsap\APLP2::Hsap\APP^{Scer\UAS.T:Hsap\MYC} (Fossgreen et al., 1998) visible, with LIMK1^{D522A.Scer\UAS} (Chen et al., 2004) visible, with Magi^Scer\UAS.cBa (Beller et al., 2002, Beller et al., 2002) visible, with numb^{F195V.Scer\UAS.T:Hsap\MYC} (Yaich et al., 1998) visible, with Psn^+14.Scer\UAS (Ye and Fortini, 1999) visible, with ptc^{Δ1.2C.Scer\UAS}, ptc¹⁰ (Lu et al., 2006) visible, with ptc^{Δ1.2C.Scer\UAS}/ptc¹⁰ (Lu et al., 2006) visible, with smo^{dsRNA.Scer\UAS.WIZ} (Casso et al., 2008) visible, with Tip60^{Scer\UAS.Scer\UAS.cSa} (Schirling et al., 2010) visible, with w^{dsRNA.Scer\UAS.cNa} (Negeri et al., 2002)
Phenotype Manifest In
	abdominal sternite 6, with tra2^{dsRNA.Scer\UAS} (Fortier and Belote, 2000) abdominal tergite 5, with tra2^{dsRNA.Scer\UAS} (Fortier and Belote, 2000) abdominal tergite 6, with tra2^{dsRNA.Scer\UAS} (Fortier and Belote, 2000) abdominal tergite 7, with tra2^{dsRNA.Scer\UAS} (Fortier and Belote, 2000) anal plate, with tra2^{dsRNA.Scer\UAS} (Fortier and Belote, 2000) arista lateral \| ectopic, with th^Scer\UAS.cHa (Cullen and McCall, 2004) embryonic/larval brain, with vn^{ΔIg.Scer\UAS} (Donaldson et al., 2004) eye, with Magi^Scer\UAS.cBa (Beller et al., 2002, Beller et al., 2002) female genitalia, with tra2^{dsRNA.Scer\UAS} (Fortier and Belote, 2000) femur, with LIMK1^{D522A.Scer\UAS} (Chen et al., 2004) imaginal disc, with vn^{ΔIg.Scer\UAS} (Donaldson et al., 2004) leg, with LIMK1^{D522A.Scer\UAS} (Chen et al., 2004) macrochaeta, with numb^{F195V.Scer\UAS.T:Hsap\MYC} (Yaich et al., 1998) male genitalia, with tnc^{dsRNA.Scer\UAS.cFa} (Fraichard et al., 2010) medial triple row \| ectopic, with Hsap\SMAD4^{100T.Scer\UAS} (Takaesu et al., 2005) ommatidium, with Magi^Scer\UAS.cBa (Beller et al., 2002, Beller et al., 2002) pigment cell, with w^{dsRNA.Scer\UAS.cNa} (Negeri et al., 2002) scutellar bristle \| ectopic, with ed^Ext.Scer\UAS (Ahmed et al., 2003) scutellar bristle \| supernumerary, with Magi^Scer\UAS.cBa (Beller et al., 2002, Beller et al., 2002) sensillum campaniformium, with Hsap\SMAD4^{100T.Scer\UAS} (Takaesu et al., 2005) sex comb, with tra2^{dsRNA.Scer\UAS} (Fortier and Belote, 2000) tibia, with LIMK1^{D522A.Scer\UAS} (Chen et al., 2004) wing, with Hsap\APLP2::Hsap\APP^{Scer\UAS.T:Hsap\MYC} (Fossgreen et al., 1998) wing, with LIMK1^{D522A.Scer\UAS} (Chen et al., 2004) wing, with Mad^Scer\UAS.cNa (Takaesu et al., 2012) wing, with mbl^B.Scer\UAS (Vicente-Crespo et al., 2008) wing, with Psn^+14.Scer\UAS (Ye and Fortini, 1999) wing, with Snoo^Scer\UAS.cTa (Takaesu et al., 2012) wing, with Tip60^{Scer\UAS.Scer\UAS.cSa} (Schirling et al., 2010) wing, with tkv^{Q199D.Scer\UAS.T:Ivir\HA1} (Takaesu et al., 2012) wing \| anterior compartment, with ptc^{Δ1.2C.Scer\UAS}, ptc¹⁰ (Lu et al., 2006) wing \| anterior compartment, with ptc^{Δ1.2C.Scer\UAS}/ptc¹⁰ (Lu et al., 2006) wing \| distal, with ed^Ext.Scer\UAS (Ahmed et al., 2003) wing disc, with arm^ΔN.Scer\UAS (Nagaraj et al., 1999) wing vein, with fuss^Scer\UAS.cTa (Takaesu et al., 2012) wing vein, with mbl^A.Scer\UAS (Vicente-Crespo et al., 2008) wing vein, with Psn^+14.Scer\UAS (Ye and Fortini, 1999) wing vein, with ptc^{Δ1.2C.Scer\UAS}, ptc¹⁰ (Lu et al., 2006) wing vein, with ptc^{Δ1.2C.Scer\UAS}/ptc¹⁰ (Lu et al., 2006) wing vein \| ectopic, with Bap170^{dsRNA.Scer\UAS.cRa} (Rendina et al., 2010) wing vein \| ectopic, with Tip60^{Scer\UAS.Scer\UAS.cSa} (Schirling et al., 2010) wing vein L2, with cv-c^{dsRNA.Scer\UAS} (Billuart et al., 2001) wing vein L2, with ed^Ext.Scer\UAS (Ahmed et al., 2003) wing vein L3, with smo^{dsRNA.Scer\UAS.WIZ} (Casso et al., 2008) wing vein L4, with smo^{dsRNA.Scer\UAS.WIZ} (Casso et al., 2008)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement Reference Scer\GAL4^T80, tkv^{Q199D.Scer\UAS.T:Ivir\HA1} has wing phenotype, suppressible by Scer\GAL4^T80, tkv^{Q199D.Scer\UAS.T:Ivir\HA1} (Takaesu et al., 2012, Takaesu et al., 2012)
NOT suppressed by
Statement Reference fuss^Scer\UAS.cTa, Scer\GAL4^T80 has wing phenotype, non-suppressible by tkv^{Q199D.Scer\UAS.T:Ivir\HA1}, Scer\GAL4^T80 (Takaesu et al., 2012, Takaesu et al., 2012)
Suppressor of
Statement Reference Scer\GAL4^T80, tkv^{Q199D.Scer\UAS.T:Ivir\HA1} is a suppressor of wing phenotype of Scer\GAL4^T80, tkv^{Q199D.Scer\UAS.T:Ivir\HA1} (Takaesu et al., 2012, Takaesu et al., 2012) tkv^{Q253D.Scer\UAS.cNb}/Scer\GAL4^T80 is a suppressor of FlyBase_internalproperty type:organism:organism \| dorsal closure stage phenotype of Sec61α¹ (Wang and Ward, 2010)
NOT Suppressor of
Statement Reference Scer\GAL4^T80/Nc^{CARD.Scer\UAS} is a non-suppressor of wing disc \| somatic clone phenotype of dm⁴ (Neto-Silva et al., 2010) tkv^{Q199D.Scer\UAS.T:Ivir\HA1}, Scer\GAL4^T80 is a non-suppressor of wing phenotype of fuss^Scer\UAS.cTa, Scer\GAL4^T80 (Takaesu et al., 2012, Takaesu et al., 2012) yki^Scer\UAS.cHa, Scer\GAL4^T80, Nc^{CARD.Scer\UAS} is a non-suppressor of wing disc \| somatic clone phenotype of dm⁴ (Neto-Silva et al., 2010)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Mer^{1-600.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 rescues Mer⁴ (LaJeunesse et al., 1998) Mer^{Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 rescues Mer⁴ (LaJeunesse et al., 1998) Moe^{T559D.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 rescues Moe^G0323 (Speck et al., 2003) Nrx-1^Scer\UAS.cLa/Scer\GAL4^T80 rescues Nrx-1²⁷³/Df(3R)5C1 (Li et al., 2007) pzg^Scer\UAS.cEa/Scer\GAL4^T80 rescues pzg^1.3 (Eggert et al., 2004) Scer\GAL4^T80/Moe^{Scer\UAS.T:Hsap\MYC} rescues Moe^G0323 (Speck et al., 2003) Sip1^{Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 rescues Sip1⁰⁶³⁷³ (Hughes et al., 2010) WASp^Scer\UAS.cBa/Scer\GAL4^T80 rescues Df(3R)3450/WASp¹ (Tal et al., 2002) WASp^Scer\UAS.cBa/Scer\GAL4^T80 rescues WASp^unspecified (Ben-Yaacov et al., 2001) wds^Scer\UAS.cHa/Scer\GAL4^T80 rescues wds^j25 (Hollmann et al., 2002)
Partially rescues	cora^{1-383.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 partially rescues cora⁸ (Ward et al., 2001) cora^{1-383.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 partially rescues cora¹⁰ (Ward et al., 2001) cora^{1-1698.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 partially rescues cora⁸ (Ward et al., 2001) cora^{1-1698.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 partially rescues cora¹⁴ (Ward et al., 2001) Gl^Scer\UAS.cLa/Scer\GAL4^T80 partially rescues Gl^G38S/Gl^l1 (Lloyd et al., 2012) Gl^Scer\UAS.cLa/Scer\GAL4^T80 partially rescues Gl^Δ22/Gl^l1 (Lloyd et al., 2012) Mer^{1-350.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 partially rescues Mer⁴ (LaJeunesse et al., 1998) Mer^{1-375.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 partially rescues Mer⁴ (LaJeunesse et al., 1998) Mer^{3.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 partially rescues Mer⁴ (LaJeunesse et al., 1998) Scer\GAL4^T80/th^Scer\UAS.cHa partially rescues th¹ (Cullen and McCall, 2004) Syx18^Scer\UAS.cGa/Scer\GAL4^T80 partially rescues Syx18^ex6 (Gorczyca et al., 2007) vn^Scer\UAS.cSa/Scer\GAL4^T80 partially rescues Df(3L)γ3/vn^L6 (Schnepp et al., 1996)
Fails to rescue	cora^{1-383.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 fails to rescue cora⁴ (Ward et al., 2001) cora^{1-383.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 fails to rescue cora⁵ (Ward et al., 2001) cora^{1-383.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 fails to rescue cora⁶ (Ward et al., 2001) cora^{1-383.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 fails to rescue cora¹⁴ (Ward et al., 2001) cora^{1-1698.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 fails to rescue cora⁵ (Ward et al., 2001) Mer^{1-169.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 fails to rescue Mer⁴ (LaJeunesse et al., 1998) Mer^{1-330.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 fails to rescue Mer⁴ (LaJeunesse et al., 1998) Mer^{351-635.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 fails to rescue Mer⁴ (LaJeunesse et al., 1998) Mer^{601-635.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 fails to rescue Mer⁴ (LaJeunesse et al., 1998) Mer^{BBA.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 fails to rescue Mer⁴ (LaJeunesse et al., 1998) Mer^{ΔBB.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 fails to rescue Mer⁴ (LaJeunesse et al., 1998) Moe^{T559A.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^T80 fails to rescue Moe^G0323 (Speck et al., 2003) Scer\GAL4^T80/Mer^{351-601.Scer\UAS.T:Hsap\MYC} fails to rescue Mer⁴ (LaJeunesse et al., 1998)
Comments
Stocks ( 2 )
Bloomington	1878 w^*; P{GawB}T80/CyO
Kyoto	106551 w^*; P{GawB}T80/CyO
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	GAL4^T80 Scer\GAL4^T80 T80 (LaJeunesse et al., 1998, Rorth, 1996)
Name Synonym
Secondary FlyBase IDs

References ( 62 )

Generate a list of	All references relating to this allele ( 62 )

List References by type	Research paper ( 61 ) Personal communication to FlyBase ( 1 )
Recent research papers ( 5 )
	Casso et al., 2012, PLoS ONE 7(3): e33827 Expression and Characterization of Drosophila Signal Peptide Peptidase-Like (sppL), a Gene That Encodes an Intramembrane Protease. [FBrf0217861] Gutiérrez et al., 2012, Development 139(1): 117--127 The role of the histone H2A ubiquitinase Sce in Polycomb repression. [FBrf0216868] Lloyd et al., 2012, Neuron 74(2): 344--360 The p150(Glued) CAP-Gly Domain Regulates Initiation of Retrograde Transport at Synaptic Termini. [FBrf0218160] Takaesu et al., 2012, Development 139(18): 3392--3401 Drosophila CORL is required for Smad2-mediated activation of Ecdysone Receptor expression in the mushroom body. [FBrf0219224] Hyun and Hashimoto, 2011, Fly 5(1): 53--57 Physiological effects of manipulating the level of insulin-degrading enzyme in insulin-producing cells of Drosophila. [FBrf0213028] Show all research papers ...

Allele Scer\GAL4T80

Allele Scer\GAL4^T80