FlyBase Allele Report: Scer\GAL4[T80]

Expression in the midgut is found in a distinct group of Dh31-expressing enteroendocrine cells located at the junction region of the anterior midgut and the acid-secreting portion of the larval midgut. This junction region occurs at a conspicuous and characteristic U-shaped bend in the gut. These are referred to as the "midgut junction Dh31-expressing cells".

(Lajeunesse et al., 2010)

Expression of Scer\GAL4^T80 is described as being pan-imaginal discs.

(Billuart et al., 2001)

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate | larval stage, with kay^dsRNA.UAS

(Hyun et al., 2006)

abnormal eye color, with w^{dsRNA.UAS.cNa}

(Negeri et al., 2002)

abnormal mitotic cell cycle, with kay^dsRNA.UAS

(Hyun et al., 2006)

abnormal size | larval stage, with vn^ΔIg.UAS

(Donaldson et al., 2004)

decreased occurrence of cell division | larval stage, with vn^ΔIg.UAS

(Donaldson et al., 2004)

fertile, with LIMK1^D522A.UAS

(Chen et al., 2004)

increased cell death | somatic clone, with hep^Act.UAS

(Külshammer and Uhlirova, 2013)

lethal, with bab1^UAS.cGa

(Bardot et al., 2002)

lethal, with bab2^4.UAS

(Bardot et al., 2002)

lethal, with BacA\p35^UAS.cHa

(Morris et al., 2006)

lethal, with Baldspot^{dsRNA.UAS.cJa}

(Jung et al., 2007)

lethal, with CycE^UAS.cLa

(Morris et al., 2006)

lethal, with Dad^UAS.cTa

(Marquez et al., 2001)

lethal, with dap^UAS.cdNa

(Morris et al., 2006)

lethal, with E2f1^UAS.cNa

(Morris et al., 2006)

lethal, with EP115^EP115

(Rorth, 1996)

lethal, with Hsap\CDKN1A^UAS.cHa

(Morris et al., 2006)

lethal, with Hsap\KMT2A::Hsap\AFF1^UAS.cMa

(Muyrers-Chen et al., 2004)

lethal, with Hsap\KMT2A::Hsap\MLLT3^{UAS.C.Tag:FLAG}

(Muyrers-Chen et al., 2004)

lethal, with kay^dsRNA.UAS

(Hyun et al., 2006)

lethal, with LamC^ΔN.UAS.cSa

(Schulze et al., 2009)

lethal, with peb^EP55

(Rorth, 1996)

lethal, with pzg^UAS.cEa

(Eggert et al., 2004)

lethal, with RhoGAP93B^dsRNA.UAS

(Billuart et al., 2001)

lethal, with rpr^UAS.cZa

(Morris et al., 2006)

lethal, with tra2^UAS.Tag:MYC

(Qi et al., 2006)

lethal | heat sensitive, with Tip60^{dsRNA.UAS.cSa}

(Schirling et al., 2010)

lethal | larval stage, with Dref^{dsRNA.h-h.UAS}

(Yoshida et al., 2004)

lethal | pupal stage, with Dref^{dsRNA.h-h.UAS}

(Yoshida et al., 2004)

lethal - all die before end of larval stage, with GEFmeso^UAS.cBa

(Blanke and Jackle, 2006)

lethal - all die before end of larval stage, with sktl^UAS.cHa

(Hassan et al., 1998)

lethal - all die before end of P-stage, with rk^GD14383

(Loveall and Deitcher, 2010)

lethal - all die during embryonic stage, with Bx42^dsRNA.UAS

(Negeri et al., 2002)

partially lethal, with Hsap\APP^695.UAS.cYa

(Yagi et al., 2000)

partially lethal - majority die, with LamC^W557S.UAS

(Schulze et al., 2009)

partially lethal - majority die, with su(sable)^UAS.cTa

(Turnage et al., 2000)

partially lethal - majority die, with tum^{dsRNA.UAS.cBa}

(Billuart et al., 2001)

partially lethal - majority live, with Mad^1.UAS

(Takaesu et al., 2005)

some die during embryonic stage, with Bx42^dsRNA.UAS

(Negeri et al., 2002)

some die during larval stage, with GEFmeso^UAS.cBa

(Blanke and Jackle, 2006)

some die during larval stage, with sktl^UAS.cHa

(Hassan et al., 1998)

some die during pharate adult stage, with rk^GD14383

(Loveall and Deitcher, 2010)

viable, with f^{dsRNA.UAS.fIR}

(Maxwell et al., 2008)

viable, with Hsap\KMT2A^{UAS.C.Tag:FLAG}

(Muyrers-Chen et al., 2004)

viable, with Ide^dsRNA.UAS

(Hyun and Hashimoto, 2011)

viable, with LamC^hs.PSb

(Schulze et al., 2009)

viable, with LamC^K493W.UAS

(Schulze et al., 2009)

viable, with LamC^L567P.UAS

(Schulze et al., 2009)

viable, with LamC^N210K.UAS

(Schulze et al., 2009)

viable, with LamC^R401K.UAS

(Schulze et al., 2009)

viable, with LamC^ΔC.UAS

(Schulze et al., 2009)

viable, with LIMK1^D522A.UAS

(Chen et al., 2004)

viable, with Tk^{dsRNA.UAS.cWa}

(Winther et al., 2006)

viable, with tra2^dsRNA.UAS

(Maxwell et al., 2008)

visible, with Bap170^{dsRNA.UAS.cRa}

(Rendina et al., 2010)

visible, with cv-c^dsRNA.UAS

(Billuart et al., 2001)

visible, with ed^Ext.UAS

(Ahmed et al., 2003)

visible, with Hsap\APLP2::Hsap\APP^UAS.Tag:MYC

(Fossgreen et al., 1998)

visible, with Hsap\APP^695.UAS.cYa

(Yagi et al., 2000)

visible, with LIMK1^D522A.UAS

(Chen et al., 2004)

visible, with Magi^UAS.cBa

(Beller et al., 2002, Beller et al., 2002)

visible, with numb^{F195V.UAS.Tag:MYC}

(Yaich et al., 1998)

visible, with Psn^+14.UAS

(Ye and Fortini, 1999)

visible, with ptc^Δ1.2C.UAS, ptc¹⁰

(Lu et al., 2006)

visible, with ptc^Δ1.2C.UAS/ptc¹⁰

(Lu et al., 2006)

visible, with smo^{dsRNA.UAS.WIZ}

(Casso et al., 2008)

visible, with Tip60^{dsRNA.UAS.cSa}

(Schirling et al., 2010)

visible, with w^{dsRNA.UAS.cNa}

(Negeri et al., 2002)

Phenotype Manifest In

abdominal sternite 6, with tra2^dsRNA.UAS

(Fortier and Belote, 2000)

abdominal tergite 5, with tra2^dsRNA.UAS

(Fortier and Belote, 2000)

abdominal tergite 6, with tra2^dsRNA.UAS

(Fortier and Belote, 2000)

abdominal tergite 7, with tra2^dsRNA.UAS

(Fortier and Belote, 2000)

arista lateral | ectopic, with Diap1^UAS.cHa

(Cullen and McCall, 2004)

campaniform sensillum, with Hsap\SMAD4^100T.UAS

(Takaesu et al., 2005)

cercus, with tra2^dsRNA.UAS

(Fortier and Belote, 2000)

embryonic/larval brain, with vn^ΔIg.UAS

(Donaldson et al., 2004)

enteroblast | adult stage, with zfh2^EAB

(Rojas Villa et al., 2019)

eye, with Magi^UAS.cBa

(Beller et al., 2002, Beller et al., 2002)

female genitalia, with tra2^dsRNA.UAS

(Fortier and Belote, 2000)

femur, with LIMK1^D522A.UAS

(Chen et al., 2004)

imaginal disc, with vn^ΔIg.UAS

(Donaldson et al., 2004)

leg, with Hsap\APP^695.UAS.cYa

(Yagi et al., 2000)

leg, with LIMK1^D522A.UAS

(Chen et al., 2004)

macrochaeta, with numb^{F195V.UAS.Tag:MYC}

(Yaich et al., 1998)

male genitalia, with tnc^{dsRNA.UAS.cFa}

(Fraichard et al., 2010)

medial triple row | ectopic, with Hsap\SMAD4^100T.UAS

(Takaesu et al., 2005)

ommatidium, with Magi^UAS.cBa

(Beller et al., 2002, Beller et al., 2002)

pigment cell, with w^{dsRNA.UAS.cNa}

(Negeri et al., 2002)

scutellar bristle | ectopic, with ed^Ext.UAS

(Ahmed et al., 2003)

scutellar bristle | increased number, with Magi^UAS.cBa

(Beller et al., 2002, Beller et al., 2002)

sex comb, with tra2^dsRNA.UAS

(Fortier and Belote, 2000)

tibia, with LIMK1^D522A.UAS

(Chen et al., 2004)

wing, with Hsap\APLP2::Hsap\APP^UAS.Tag:MYC

(Fossgreen et al., 1998)

wing, with Hsap\APP^695.UAS.cYa

(Yagi et al., 2000)

wing, with LIMK1^D522A.UAS

(Chen et al., 2004)

wing, with Mad^UAS.cNa

(Takaesu et al., 2012)

wing, with mbl^B.UAS

(Vicente-Crespo et al., 2008)

wing, with Psn^+14.UAS

(Ye and Fortini, 1999)

wing, with Snoo^UAS.cTa

(Takaesu et al., 2012)

wing, with Tip60^{dsRNA.UAS.cSa}

(Schirling et al., 2010)

wing, with tkv^{Q199D.UAS.Tag:HA}

(Takaesu et al., 2012)

wing | distal, with ed^Ext.UAS

(Ahmed et al., 2003)

wing blade anterior compartment, with ptc^Δ1.2C.UAS, ptc¹⁰

(Lu et al., 2006)

wing disc, with arm^ΔN.UAS

(Nagaraj et al., 1999)

wing vein, with fuss^UAS.cTa

(Takaesu et al., 2012)

wing vein, with mbl^A.UAS

(Vicente-Crespo et al., 2008)

wing vein, with Psn^+14.UAS

(Ye and Fortini, 1999)

wing vein, with ptc^Δ1.2C.UAS, ptc¹⁰

(Lu et al., 2006)

wing vein, with ptc^Δ1.2C.UAS/ptc¹⁰

(Lu et al., 2006)

wing vein | ectopic, with Bap170^{dsRNA.UAS.cRa}

(Rendina et al., 2010)

wing vein | ectopic, with Tip60^{dsRNA.UAS.cSa}

(Schirling et al., 2010)

wing vein L2, with cv-c^dsRNA.UAS

(Billuart et al., 2001)

wing vein L2, with ed^Ext.UAS

(Ahmed et al., 2003)

wing vein L3, with smo^{dsRNA.UAS.WIZ}

(Casso et al., 2008)

wing vein L4, with smo^{dsRNA.UAS.WIZ}

(Casso et al., 2008)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹ has abnormal cell migration | somatic clone phenotype, suppressible by cher^KK107518, Scer\GAL4^T80

(Külshammer and Uhlirova, 2013)

Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹ has abnormal cell migration | somatic clone phenotype, suppressible by cher¹

(Külshammer and Uhlirova, 2013)

Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹ has lethal - all die during third instar larval stage phenotype, suppressible | partially by cher¹

(Külshammer and Uhlirova, 2013)

Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹ has abnormal cell migration | somatic clone phenotype, suppressible by zip^GD1566, Scer\GAL4^T80

(Külshammer and Uhlirova, 2013)

Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹ has neoplasia | somatic clone phenotype, suppressible by zip^GD1566, Scer\GAL4^T80

(Külshammer and Uhlirova, 2013)

NOT suppressed by

Statement

Reference

Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹ has abnormal mitotic cell cycle | somatic clone phenotype, non-suppressible by cher^KK107518, Scer\GAL4^T80

(Külshammer and Uhlirova, 2013)

Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹ has neoplasia | somatic clone phenotype, non-suppressible by cher^KK107518, Scer\GAL4^T80

(Külshammer and Uhlirova, 2013)

Suppressor of

Statement

Reference

Hsap\NF2^{UAS.Iso1.Tag:FLAG}/Scer\GAL4^T80 is a suppressor | partially of lethal phenotype of Mer⁴

(Gavilan et al., 2014)

Scer\GAL4^T80/Hsap\NF2^{UAS.Iso2.Tag:FLAG} is a suppressor | partially of lethal phenotype of Mer⁴

(Gavilan et al., 2014)

Hsap\NF2^{L64P.UAS.Tag:FLAG}/Scer\GAL4^T80 is a suppressor | partially of lethal phenotype of Mer⁴

(Gavilan et al., 2014)

Hsap\NF2^{K413E.UAS.Tag:FLAG}/Scer\GAL4^T80 is a suppressor | partially of lethal phenotype of Mer⁴

(Gavilan et al., 2014)

Hsap\NF2^{R466X.UAS.Tag:FLAG}/Scer\GAL4^T80 is a suppressor | partially of lethal phenotype of Mer⁴

(Gavilan et al., 2014)

cher^KK107518, Scer\GAL4^T80 is a suppressor of abnormal cell migration | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹

(Külshammer and Uhlirova, 2013)

zip^GD1566, Scer\GAL4^T80 is a suppressor of abnormal cell migration | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹

(Külshammer and Uhlirova, 2013)

zip^GD1566, Scer\GAL4^T80 is a suppressor of neoplasia | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹

(Külshammer and Uhlirova, 2013)

NOT Suppressor of

Statement

Reference

Hsap\NF2^{Δ2-3.UAS.Tag:FLAG}/Scer\GAL4^T80 is a non-suppressor of lethal phenotype of Mer⁴

(Gavilan et al., 2014)

Hsap\NF2^{1-301.UAS.Tag:FLAG}/Scer\GAL4^T80 is a non-suppressor of lethal phenotype of Mer⁴

(Gavilan et al., 2014)

Scer\GAL4^T80/Hsap\NF2^{351-595.UAS.Tag:FLAG} is a non-suppressor of lethal phenotype of Mer⁴

(Gavilan et al., 2014)

Hsap\NF2^{1-356.UAS.Tag:FLAG}/Scer\GAL4^T80 is a non-suppressor of lethal phenotype of Mer⁴

(Gavilan et al., 2014)

Hsap\NF2^{300-595.UAS.Tag:FLAG}/Scer\GAL4^T80 is a non-suppressor of lethal phenotype of Mer⁴

(Gavilan et al., 2014)

cher^KK107518, Scer\GAL4^T80 is a non-suppressor of abnormal mitotic cell cycle | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹

(Külshammer and Uhlirova, 2013)

cher^KK107518, Scer\GAL4^T80 is a non-suppressor of neoplasia | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹

(Külshammer and Uhlirova, 2013)

Phenotype Manifest In

Suppressed by

Statement

Reference

Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹ has ommatidium | somatic clone phenotype, suppressible by cher¹

(Külshammer and Uhlirova, 2013)

Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹ has photoreceptor cell | somatic clone phenotype, suppressible by cher¹

(Külshammer and Uhlirova, 2013)

Scer\GAL4^T80, tkv^{Q199D.UAS.Tag:HA} has wing phenotype, suppressible by Scer\GAL4^T80, tkv^{Q199D.UAS.Tag:HA}

(Takaesu et al., 2012)

NOT suppressed by

Statement

Reference

Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹ has eye-antennal disc | somatic clone phenotype, non-suppressible by cher^KK107518, Scer\GAL4^T80

(Külshammer and Uhlirova, 2013)

fuss^UAS.cTa, Scer\GAL4^T80 has wing phenotype, non-suppressible by tkv^{Q199D.UAS.Tag:HA}, Scer\GAL4^T80

(Takaesu et al., 2012)

Suppressor of

Statement

Reference

Scer\GAL4^T80, tkv^{Q199D.UAS.Tag:HA} is a suppressor of wing phenotype of Scer\GAL4^T80, tkv^{Q199D.UAS.Tag:HA}

(Takaesu et al., 2012)

NOT Suppressor of

Statement

Reference

cher^KK107518, Scer\GAL4^T80 is a non-suppressor of eye-antennal disc | somatic clone phenotype of Ras85D^V12.UAS, Scer\GAL4^T80, scrib¹

(Külshammer and Uhlirova, 2013)

tkv^{Q199D.UAS.Tag:HA}, Scer\GAL4^T80 is a non-suppressor of wing phenotype of fuss^UAS.cTa, Scer\GAL4^T80

(Takaesu et al., 2012)

Scer\GAL4^T80/Dronc^CARD.UAS is a non-suppressor of wing disc | somatic clone phenotype of Myc⁴

(Neto-Silva et al., 2010)

yki^UAS.cHa, Scer\GAL4^T80, Dronc^CARD.UAS is a non-suppressor of wing disc | somatic clone phenotype of Myc⁴

(Neto-Silva et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

CG10939^UAS.Tag:MYC/Scer\GAL4^T80 rescues CG10939⁰⁶³⁷³

(Hughes et al., 2010)

Nrx-1^UAS.cLa/Scer\GAL4^T80 rescues Nrx-1²⁷³/Df(3R)5C1

(Li et al., 2007)

pzg^UAS.cEa/Scer\GAL4^T80 rescues pzg^1.3

(Eggert et al., 2004)

Moe^{T559D.UAS.Tag:MYC}/Scer\GAL4^T80 rescues Moe^G0323

(Speck et al., 2003)

Scer\GAL4^T80/Moe^UAS.Tag:MYC rescues Moe^G0323

(Speck et al., 2003)

wds^UAS.cHa/Scer\GAL4^T80 rescues wds^j25

(Hollmann et al., 2002)

WASp^UAS.cBa/Scer\GAL4^T80 rescues Df(3R)3450/WASp¹

(Tal et al., 2002)

WASp^UAS.cBa/Scer\GAL4^T80 rescues WASp^unspecified

(Ben-Yaacov et al., 2001)

Mer^{1-600.UAS.Tag:MYC}/Scer\GAL4^T80 rescues Mer⁴

(LaJeunesse et al., 1998)

Mer^UAS.Tag:MYC/Scer\GAL4^T80 rescues Mer⁴

(LaJeunesse et al., 1998)

Partially rescues

Kdm5^UASp.cSa/Scer\GAL4^T80 partially rescues Kdm5¹⁴⁰

(Drelon et al., 2019)

DCTN1-p150^UAS.cLa/Scer\GAL4^T80 partially rescues DCTN1-p150^Δ22/DCTN1-p150^l1

(Lloyd et al., 2012)

DCTN1-p150^UAS.cLa/Scer\GAL4^T80 partially rescues DCTN1-p150^G38S/DCTN1-p150^l1

(Lloyd et al., 2012)

Syx18^UAS.cGa/Scer\GAL4^T80 partially rescues Syx18^ex6

(Gorczyca et al., 2007)

Scer\GAL4^T80/Diap1^UAS.cHa partially rescues Diap1¹

(Cullen and McCall, 2004)

cora^{1-1698.UAS.Tag:MYC}/Scer\GAL4^T80 partially rescues cora¹⁴

(Ward et al., 2001)

cora^{1-1698.UAS.Tag:MYC}/Scer\GAL4^T80 partially rescues cora⁸

(Ward et al., 2001)

cora^{1-383.UAS.Tag:MYC}/Scer\GAL4^T80 partially rescues cora¹⁰

(Ward et al., 2001)

cora^{1-383.UAS.Tag:MYC}/Scer\GAL4^T80 partially rescues cora⁸

(Ward et al., 2001)

Mer^{1-375.UAS.Tag:MYC}/Scer\GAL4^T80 partially rescues Mer⁴

(LaJeunesse et al., 1998)

Mer^{1-350.UAS.Tag:MYC}/Scer\GAL4^T80 partially rescues Mer⁴

(LaJeunesse et al., 1998)

Mer^{3.UAS.Tag:MYC}/Scer\GAL4^T80 partially rescues Mer⁴

(LaJeunesse et al., 1998)

vn^UAS.cSa/Scer\GAL4^T80 partially rescues Df(3L)γ3/vn^L6

(Schnepp et al., 1996)

Fails to rescue

Moe^{T559A.UAS.Tag:MYC}/Scer\GAL4^T80 fails to rescue Moe^G0323

(Speck et al., 2003)

cora^{1-1698.UAS.Tag:MYC}/Scer\GAL4^T80 fails to rescue cora⁵

(Ward et al., 2001)

cora^{1-383.UAS.Tag:MYC}/Scer\GAL4^T80 fails to rescue cora¹⁴

(Ward et al., 2001)

cora^{1-383.UAS.Tag:MYC}/Scer\GAL4^T80 fails to rescue cora⁴

(Ward et al., 2001)

cora^{1-383.UAS.Tag:MYC}/Scer\GAL4^T80 fails to rescue cora⁶

(Ward et al., 2001)

cora^{1-383.UAS.Tag:MYC}/Scer\GAL4^T80 fails to rescue cora⁵

(Ward et al., 2001)

Mer^{ΔBB.UAS.Tag:MYC}/Scer\GAL4^T80 fails to rescue Mer⁴

(LaJeunesse et al., 1998)

Mer^{1-169.UAS.Tag:MYC}/Scer\GAL4^T80 fails to rescue Mer⁴

(LaJeunesse et al., 1998)

Mer^{351-635.UAS.Tag:MYC}/Scer\GAL4^T80 fails to rescue Mer⁴

(LaJeunesse et al., 1998)

Scer\GAL4^T80/Mer^{351-601.UAS.Tag:MYC} fails to rescue Mer⁴

(LaJeunesse et al., 1998)

Mer^{1-330.UAS.Tag:MYC}/Scer\GAL4^T80 fails to rescue Mer⁴

(LaJeunesse et al., 1998)

Mer^{BBA.UAS.Tag:MYC}/Scer\GAL4^T80 fails to rescue Mer⁴

(LaJeunesse et al., 1998)

Mer^{601-635.UAS.Tag:MYC}/Scer\GAL4^T80 fails to rescue Mer⁴

(LaJeunesse et al., 1998)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

1878

106551

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

GAL4^T80

Scer\GAL4^T80

T80

(LaJeunesse et al., 1998, Rorth, 1996)

Name Synonyms

Secondary FlyBase IDs

References (80)

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