A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Allele Scer\GAL4elav.PLu

General Information
SymbolScer\GAL4elav.PLuSpeciesS. cerevisiae
Nameembryonic lethal, abnormal vision promoter construct of LuoFlyBase IDFBal0042579
Feature typealleleAssociated geneScer\GAL4
Allele class
Mutagenin vitro construct - regulatory fusion
hide Recent Updates
Description
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Update Feed
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Progenitor genotype
Nature of the lesion
Statement
Reference
Construct: Scer\GAL4 expression is driven by an elav promoter.
Carried in construct
(Ayoob et al., 2004, Rohrbough et al., 2004, Banerjee et al., 2004, Yoshida et al., 2004, Yapici et al., 2008, Sanchez-Soriano and Prokop, 2005, Kolesnikov and Beckendorf, 2005, Labrador et al., 2005, Murthy et al., 2003, Sweeney and Davis, 2002, Ruan et al., 2002, Zhang et al., 2005, Tsuda et al., 2002, Haghighi et al., 2003, Bhat, 2005, Sanyal et al., 2002, Kazantsev et al., 2002, Kaufmann et al., 2002, Dworak et al., 2001, Huang and Stern, 2002, Adam et al., 2003, Sanchez-Soriano et al., 2005, Hou et al., 2003, Madden et al., 1999, Taniguchi et al., 2000, Drapeau et al., 2003, Featherstone et al., 2002, Scott et al., 2003, Crowner et al., 2003, Fergestad et al., 2006, Hu et al., 2001, Kaufmann et al., 1998, Winberg et al., 2001, Keleman and Dickson, 2001, Suster and Bate, 2002, Suh et al., 2002, Osterwalder et al., 2001, Pitman et al., 2002, Samson and Chalvet, 2003, Pipes et al., 2001, Kidd et al., 1998, Rao and Zipursky, 1998, Bergmann et al., 2002, Yoshida et al., 2001, Yoshikawa et al., 2003, Hidalgo et al., 2001, Bashaw et al., 2001, Zordan et al., 2006, Renden et al., 2001, Liu et al., 2006, Saitoe et al., 2001, Deshpande et al., 2001, Hu et al., 2005, Hu, 2005, Steffan et al., 2001, Liu et al., 2003, Tschaepe et al., 2002, Haines and Stewart, 2007, Chang et al., 2008, Edenfeld et al., 2007, Kracklauer et al., 2007, Clark et al., 2002, Terman et al., 2002, Mackler et al., 2002, Terman et al., 2002, Keleman et al., 2002, Fritz and VanBerkum, 2002, Takamatsu et al., 2002, Chalvet and Samson, 2002, Moore et al., 2002, Wills et al., 2002, Rodan et al., 2002, Bach et al., 2003, Lee et al., 2004, Fradkin et al., 2004, Kim et al., 2002, Gallio et al., 2004, Robinson et al., 2002, Lee et al., 2004, Coyle et al., 2004, McCabe et al., 2004, Wang et al., 2009, Kumar et al., 2009, Fan et al., 2003, Georgiou and Tear, 2002, Kuppers-Munther et al., 2004, Wolfgang et al., 2004, Poskanzer et al., 2003, Balan et al., 2008, Bottenberg et al., 2009, Johnson et al., 2004, Wang et al., 2003, Chang et al., 2003, Shulman and Feany, 2003, Certel et al., 2000, Sigrist et al., 2000, Marek et al., 2000, Featherstone et al., 2000, Simpson et al., 2000, Rajagopalan et al., 2000, Luo et al., 1994, Feany and Bender, 2000, Sone et al., 2000, Kinrade et al., 2001, Simpson et al., 2000, Bashaw et al., 2000, Yannoni and White, 1999, Ray et al., 1999, Gao et al., 1999, Zars et al., 2000, Wills et al., 1999, Ma and Haddad, 1999, Benveniste et al., 1998, Kidd et al., 1999, Littleton et al., 1999, Noordermeer et al., 1998, Winberg et al., 1998, Garrity et al., 1999, Bashaw and Goodman, 1999, Hekmat-Scafe et al., 2005, Rosenzweig et al., 2005, Thomas et al., 1997, Bernardoni et al., 1997, Davis et al., 1997, Fischer et al., 2004, Tanaka et al., 2004, Miguel-Aliaga et al., 2004, Broihier et al., 2004, Whited et al., 2004, van Roessel et al., 2004, Stebbins and Yin, 2001, Koizumi et al., 2001, Mackler and Reist, 2001, Reiter et al., 1996, Saitoe et al., 2001, Wittmann et al., 2001, Sink et al., 2001, Bernardoni et al., 1998, Hoang and Chiba, 1998, Schneider et al., 1995, Kim et al., 2003, Rothenberg et al., 2003, Krueger et al., 2003, Schuster et al., 1996, Thomas et al., 1997, Thor and Thomas, 1997, Sone et al., 1997, Mitchell et al., 1996, Kidd et al., 1998, Giniger, 1998, Hickey et al., 2006, Whited et al., 2007, Labrador, 2005, Chen et al., 2006, Wang et al., 2006, Soller et al., 2006, Laviolette et al., 2005, Speder et al., 2006, Augustin et al., 2007, Sun et al., 2006, Wang et al., 2007, Schroll et al., 2006, Wang et al., 2006, Yoshimura et al., 2006, Boyle et al., 2006, Duong et al., 2008, Luan et al., 2006, Girard et al., 2006, Umeda-Kameyama et al., 2007, Meyer and Aberle, 2006, Outeiro et al., 2007, Huelsmeier et al., 2007, Deshpande et al., 2007, Wu et al., 2005, Liu et al., 2007, Dietzl et al., 2007, Zarnescu et al., 2005, Wang et al., 2007, Stowers and Isacoff, 2007, Zhu et al., 2008, Beuchle et al., 2007, Grosjean et al., 2008, Umemiya et al., 2002, Stewart et al., 2002, Mondal et al., 2007, Weng et al., 2011, Pandey et al., 2011, Hafer et al., 2011, Loya et al., 2009, Bao et al., 2011, Parker et al., 2011, Miller et al., 2011, Striegel et al., 2012, Joly et al., 2007, Menzel et al., 2007, Carvalho et al., 2010, Coffee et al., 2012, Weiss et al., 2012, Chen and Ganetzky, 2012, Dimitroff et al., 2012, Gates et al., 2007, Long et al., 2008, Huang et al., 2007, Lang et al., 2012, Kim et al., 2012, Naganos et al., 2012, Abbasi-Moheb et al., 2012, Koh et al., 2007, Wairkar et al., 2009, Poeck et al., 2008, Wu et al., 2007, Korolchuk et al., 2007, Chung et al., 2009, Sone et al., 2009, Kaplan et al., 2008, Tzortzopoulos and Skoulakis, 2007, Caldwell et al., 2008, Dickman et al., 2008, Feiguin et al., 2009, Siebert et al., 2009, Pauli et al., 2008, Miller et al., 2009, Pauli et al., 2008, Mandalaywala et al., 2008, Corl et al., 2009, O'Farrell and Kylsten, 2008, Viquez et al., 2006, Rolls et al., 2007, Kohsaka and Nose, 2009, Kohsaka et al., 2007, Jeon et al., 2008, Koch et al., 2008, Kim et al., 2002, Kamiyama and Chiba, 2009, Graf et al., 2009, Song and Tanouye, 2007, Estes et al., 2000, Agrawal et al., 2010, Ratnaparkhi et al., 2008, Poskanzer et al., 2006, Benna et al., 2010, Villányi et al., 2008, Kurusu et al., 2008, Garbe et al., 2007, Wu et al., 2008, Scantlebury et al., 2010, Chen et al., 2010, Wu et al., 2008, Fergestad et al., 2010, Scully et al., 1999, Fradkin et al., 2008, Kim et al., 2010, Higashi-Kovtun et al., 2010, Hekmat-Scafe et al., 2010, Wang et al., 2008, Chang et al., 2006, Khurana et al., 2006, Fulga et al., 2007, Bechstedt et al., 2010, Silies and Klämbt, 2010, Yoshihara et al., 2010, Nagai et al., 2010, Satoh et al., 2008, Neely et al., 2010, Lear et al., 2009, Nagai et al., 2010, Dason et al., 2010, Liang et al., 2011, Mosca and Schwarz, 2010, Bayersdorfer et al., 2010, Saja et al., 2010, Stone et al., 2008, Alic et al., 2011, Mattie et al., 2010, O'Keefe et al., 2011, Panneels et al., 2011, Kramer et al., 2011, Franco et al., 2011, Weake et al., 2011, Shen and Ganetzky, 2009, Couceiro et al., 2005, Nakai et al., 2011, Messaritou et al., 2009, Hua et al., 2011, Keleman et al., 2005, Coleman et al., 2010, Lowery et al., 2010, Raghu et al., 2009, Chang and Min, 2005, Nechipurenko and Broihier, 2012, Funderburk et al., 2009, Bricker et al., 2012, Lawlor et al., 2011, van Eyk et al., 2011, Trinh et al., 2008, Tran et al., 2012, Sasayama et al., 2012, Barone et al., 2011, Panz et al., 2012, Couthouis et al., 2012, Mosca et al., 2012, Kissler et al., 2009, Pfeiffenberger and Allada, 2012, Ben-Shahar et al., 2010, Jeong et al., 2012, Peru Y Colón de Portugal et al., 2012, Lorbeck et al., 2011, Kosmidis et al., 2010, Papanikolopoulou et al., 2010, Reinecke et al., 2011, Fujikake et al., 2008, Tanenhaus et al., 2012, Keleman et al., 2012)
Cytology
hide Phenotypic Data
hide Phenotypic Class
hide Phenotype Manifest In
abdominal posterior fascicle neuron & growth cone & filopodium, with Cdc42V12.Scer\UAS.T:Hsap\MYC
abdominal posterior fascicle neuron & growth cone & filopodium, with PakScer\UAS.T:Myr-Src64B
adherens junction & ommatidium | pupal stage P7, with mbtScer\UAS.cMa
axon & ventral nerve cord, with SoxNK439.Scer\UAS
bouton & neuromuscular junction | larval stage, with mtsdn181.Scer\UAS
dopamine neuron & adult brain, with Hsap\SNCAA30P.Scer\UAS
dopamine neuron & adult brain, with Hsap\SNCAA53T.Scer\UAS
dopamine neuron & adult brain, with Hsap\SNCAScer\UAS.cFa
dopamine neuron & adult brain, with Pink1dsRNA.Scer\UAS.cWa
filamentous actin & eye photoreceptor cell | third instar larval stage, with mbtS482N.S521E.Scer\UAS
filamentous actin & ommatidium | pupal stage P7, with mbtS482N.S521E.Scer\UAS
larval Bolwig's organ & nucleus, with GlΔ.Scer\UAS
mesothoracic les3 neuron & growth cone & filopodium, with Cdc42V12.Scer\UAS.T:Hsap\MYC
mesothoracic les3 neuron & growth cone & filopodium, with PakScer\UAS.T:Myr-Src64B
metathoracic les3 neuron & growth cone & filopodium, with Cdc42V12.Scer\UAS.T:Hsap\MYC
metathoracic les3 neuron & growth cone & filopodium, with PakScer\UAS.T:Myr-Src64B
microtubule & neuromuscular junction | larval stage, with mtsdn181.Scer\UAS
neuromuscular junction & bouton, with nejEP1179
nucleus & eye photoreceptor cell | third instar larval stage, with mbtS482N.S521E.Scer\UAS
pigment cell & retina | pupal stage P7, with mbtS482N.S521E.Scer\UAS
rhabdomere & eye photoreceptor cell, with mbtS482N.S521E.Scer\UAS
hide Detailed Description
Statement
Reference
hide External Data
Linkouts
hide Interactions
hide Phenotypic Class
hideEnhanced by
Statement
Reference
hideNOT Enhanced by
Statement
Reference
hideSuppressed by
Statement
Reference
hideNOT suppressed by
Statement
Reference
hideEnhancer of
Statement
Reference
hideNOT Enhancer of
Statement
Reference
hideSuppressor of
Statement
Reference
hideNOT Suppressor of
Statement
Reference
hide Phenotype Manifest In
hideEnhanced by
Statement
Reference
Scer\GAL4elav.PLu, mtsdn181.Scer\UAS has microtubule & neuromuscular junction | larval stage phenotype, enhanceable by PP2A-B'[+]/PP2A-B'104, Scer\GAL4elav.PLu
hideNOT Enhanced by
Statement
Reference
AblK417N.Scer\UAS, Scer\GAL4elav.PLu has phenotype, non-enhanceable by robo1
hideSuppressed by
Statement
Reference
GlΔ.Scer\UAS, Scer\GAL4elav.PLu has larval Bolwig's organ & nucleus phenotype, suppressible | partially by Khc[+]/Khc8
GlΔ.Scer\UAS, Scer\GAL4elav.PLu has larval Bolwig's organ & nucleus phenotype, suppressible | partially by Khc[+]/Khck13314
hideNOT suppressed by
Statement
Reference
hideEnhancer of
Statement
Reference
PP2A-B'[+]/PP2A-B'104, Scer\GAL4elav.PLu is an enhancer of microtubule & neuromuscular junction | larval stage phenotype of Scer\GAL4elav.PLu, mtsdn181.Scer\UAS
hideNOT Enhancer of
Statement
Reference
hideSuppressor of
Statement
Reference
hideNOT Suppressor of
Statement
Reference
cacScer\UAS.T:Avic\GFP-EGFP/Scer\GAL4elav.PLu is a non-suppressor of bouton & larval neuromuscular junction | supernumerary phenotype of Df(2R)CX1/stjk10814
hide Additional Comments
hide Genetic Interactions
Statement
Reference
hide Xenogenetic Interactions
Statement
Reference
hide Complementation & Rescue Data
Rescues
Partially rescues
Fails to rescue
Comments
hide Stocks ( 2 )
Bloomington
hide Notes on Origin
Discoverer
hide External Crossreferences & Linkouts
Other Crossreferences
Linkouts
hide Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym
elav-GAL4
GAL4elav.PLu
 
Scer\GAL4elav.PLu
 
Name Synonym
embryonic lethal, abnormal vision promoter construct of Luo
Secondary FlyBase IDs
hide References ( 322 )
Generate a list of
List References by type
hide Recent research papers ( 41 )
Abbasi-Moheb et al., 2012, Am. J. Hum. Genet. 90(5): 847--855
Mutations in NSUN2 Cause Autosomal- Recessive Intellectual Disability. [FBrf0218249]
Bricker et al., 2012, Science 337(6090): 96--100
A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans. [FBrf0218824]
Chen and Ganetzky, 2012, J. Cell Biol. 196(4): 529--543
A neuropeptide signaling pathway regulates synaptic growth in Drosophila. [FBrf0217500]
Coffee et al., 2012, Hum. Mol. Genet. 21(4): 900--915
In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation. [FBrf0217253]
Couthouis et al., 2012, Hum. Mol. Genet. 21(13): 2899--2911
Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis. [FBrf0218546]
Dimitroff et al., 2012, PLoS ONE 7(2): e30722
Diet and Energy-Sensing Inputs Affect TorC1-Mediated Axon Misrouting but Not TorC2-Directed Synapse Growth in a Drosophila Model of Tuberous Sclerosis. [FBrf0217461]
Jeong et al., 2012, Neuron 76(4): 721--734
The Control of Semaphorin-1a-Mediated Reverse Signaling by Opposing Pebble and RhoGAPp190 Functions in Drosophila. [FBrf0219982]
Keleman et al., 2012, Nature 489(7414): 145--149
Dopamine neurons modulate pheromone responses in Drosophila courtship learning. [FBrf0219398]
Kim et al., 2012, Genes Dev. 26(9): 974--987
Drosophila Neto is essential for clustering glutamate receptors at the neuromuscular junction. [FBrf0218161]
Lang et al., 2012, PLoS Genet. 8(4): e1002683
Genetic inhibition of solute-linked carrier 39 family transporter 1 ameliorates aβ pathology in a Drosophila model of Alzheimer's disease. [FBrf0218220]
Mosca et al., 2012, Nature 484(7393): 237--241
Trans-synaptic Teneurin signalling in neuromuscular synapse organization and target choice. [FBrf0218053]
Naganos et al., 2012, Neurosci. Res. 73(1): 49--55
Mutations in the Drosophila insulin receptor substrate, CHICO, impair olfactory associative learning. [FBrf0217997]
Nechipurenko and Broihier, 2012, J. Cell Biol. 196(3): 345--362
FoxO limits microtubule stability and is itself negatively regulated by microtubule disruption. [FBrf0217391]
Panz et al., 2012, Biol. Cell 104(9): 553--568
A novel role for the non-catalytic intracellular domain of Neprilysins in muscle physiology. [FBrf0219388]
Peru Y Colón de Portugal et al., 2012, J. Neurosci. 32(49): 17706--17713
Adult Neuronal Arf6 Controls Ethanol-Induced Behavior with Arfaptin Downstream of Rac1 and RhoGAP18B. [FBrf0220158]
Pfeiffenberger and Allada, 2012, PLoS Genet. 8(10): e1003003
Cul3 and the BTB Adaptor Insomniac Are Key Regulators of Sleep Homeostasis and a Dopamine Arousal Pathway in Drosophila. [FBrf0219613]
Sasayama et al., 2012, PLoS ONE 7(6): e39483
Knockdown of the Drosophila Fused in Sarcoma (FUS) Homologue Causes Deficient Locomotive Behavior and Shortening of Motoneuron Terminal Branches. [FBrf0218682]
Striegel et al., 2012, J. Neurosci. 32(4): 1253--1260
Calcium Binding by Synaptotagmin's C2A Domain is an Essential Element of the Electrostatic Switch That Triggers Synchronous Synaptic Transmission. [FBrf0217322]
Tanenhaus et al., 2012, PLoS ONE 7(10): e45130
In Vivo Circadian Oscillation of dCREB2 and NF-κB Activity in the Drosophila Nervous System. [FBrf0219734]
Tran et al., 2012, J. Biol. Chem. 287(8): 5243--5252
Multiple Members of the UDP-GalNAc: Polypeptide N-Acetylgalactosaminyltransferase Family Are Essential for Viability in Drosophila. [FBrf0217507]
Weiss et al., 2012, Genetics 190(2): 581--600
Huntingtin Aggregation Kinetics and Their Pathological Role in a Drosophila Huntington's Disease Model. [FBrf0217529]
Alic et al., 2011, Aging Cell 10(1): 137--147
Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor. [FBrf0212768]
Bao et al., 2011, J. Neurogenet. 25(4): 201--206
Overexpression of Human MRP1 in Neurons causes resistance to Antiepileptic Drugs in Drosophila Seizure Mutants. [FBrf0216724]
Barone et al., 2011, Dis. Model Mech. 4(5): 701--707
Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease. [FBrf0215025]
Franco et al., 2011, Mol. Cell. Proteomics 10(5): M110.002188
A Novel Strategy to Isolate Ubiquitin Conjugates Reveals Wide Role for Ubiquitination during Neural Development. [FBrf0213919]
Hafer et al., 2011, Genetics 189(3): 907--921
The Drosophila CPEB Protein Orb2 Has a Novel Expression Pattern and Is Important for Asymmetric Cell Division and Nervous System Function. [FBrf0216612]
Hua et al., 2011, Biol. Chem. 392(10): 919--926
Toxicity of Alzheimer's disease-associated Aβ peptide is ameliorated in a Drosophila model by tight control of zinc and copper availability. [FBrf0215055]
Kramer et al., 2011, PLoS Biol. 9(1): e1000569
Epigenetic Regulation of Learning and Memory by Drosophila EHMT/G9a. [FBrf0212836]
Lawlor et al., 2011, Hum. Mol. Genet. 20(19): 3757--3768
Double-stranded RNA is pathogenic in Drosophila models of expanded repeat neurodegenerative diseases. [FBrf0215240]
Liang et al., 2011, Cytoskeleton (Hoboken) 68(1): 1--7
NOMPC, a member of the TRP channel family, localizes to the tubular body and distal cilium of Drosophila campaniform and chordotonal receptor cells. [FBrf0212668]
Lorbeck et al., 2011, PLoS ONE 6(4): e18412
Microarray analysis uncovers a role for tip60 in nervous system function and general metabolism. [FBrf0213446]
Miller et al., 2011, J. Neurosci. 31(14): 5335--5347
Drosophila mmp2 regulates the matrix molecule faulty attraction (frac) to promote motor axon targeting in Drosophila. [FBrf0213409]
Nakai et al., 2011, J. Neurosci. 31(36): 12759--12766
Calcineurin and Its Regulator Sra/DSCR1 Are Essential for Sleep in Drosophila. [FBrf0215272]
O'Keefe et al., 2011, Mech. Dev. 128(1-2): 59--70
EndoGI modulates Notch signaling and axon guidance in Drosophila. [FBrf0213012]
Pandey et al., 2011, PLoS ONE 6(11): e28106
The Glucuronyltransferase GlcAT-P Is Required for Stretch Growth of Peripheral Nerves in Drosophila. [FBrf0216828]
Panneels et al., 2011, PLoS ONE 6(4): e18478
Drosophila photoreceptor cells exploited for the production of eukaryotic membrane proteins: receptors, transporters and channels. [FBrf0213462]
Parker et al., 2011, Genetics 187(2): 523--534
Drosophila as a Model for Epilepsy: bss Is a Gain-of-Function Mutation in the Para Sodium Channel Gene That Leads to Seizures. [FBrf0213034]
Reinecke et al., 2011, PLoS ONE 6(8): e23865
Implicating calpain in tau-mediated toxicity in vivo. [FBrf0214684]
van Eyk et al., 2011, Hum. Mol. Genet. 20(14): 2783--2794
Perturbation of the Akt/Gsk3-{beta} signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs. [FBrf0213942]
Weake et al., 2011, Genes Dev. 25(14): 1499--1509
Post-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation. [FBrf0214372]
Weng et al., 2011, J. Neurosci. 31(12): 4421--4433
The Cytoplasmic Adaptor Protein Caskin Mediates Lar Signal Transduction during Drosophila Motor Axon Guidance. [FBrf0213321]