FB2025_01 , released February 20, 2025
Allele: Dmel\Pka-C106353
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General Information
Symbol
Dmel\Pka-C106353
Species
D. melanogaster
Name
FlyBase ID
FBal0042702
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Nature of the Allele
Progenitor genotype
Associated Insertion(s)
Cytology
Description

P{PZ} insertion maps after position 71 of the 5' untranslated region.

Allele components
Component
Use(s)
Inserted element
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygotes show slow development, molting to third instar one day later than heterozygous siblings. Most die as third instar larvae. Many of the larvae surviving to the third instar remain so for up to eight days and initiate wandering behaviour but never pupariate. 15% of homozygotes do form small pupae, and about two thirds of these survive to eclose as miniature adults with unexpanded wings.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

Pka-C1[+]/Pka-C106353 is an enhancer of decreased body size | pupal stage phenotype of Nf1E2

Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

A. Spradling.

Comments
External Crossreferences and Linkouts ( 1 )
Crossreferences
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
PKA-C106353
Pka-C106353
Name Synonyms
Secondary FlyBase IDs
    References (4)