Allele Ecol\lacZ^H15-H-15

General Information
Symbol	Ecol\lacZ^H15-H-15	Species	E. coli
Name		FlyBase ID	FBal0043864
Feature type	allele	Associated gene	Ecol\lacZ

Allele class
Mutagen	Delta2-3
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	Delta2-3 (Brook et al., 1993)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference P{PZ} element located 331bp 5' to the transcription start site of H15. (Qian et al., 2005)
Caused by insertion	P{PZ}H-15 (Wilder and Perrimon, 1995, Qian et al., 2005, Sato et al., 1999, Brook et al., 1993, Griffin et al., 2000, Svendsen et al., 2000, Qian et al., 2005, Miskolczi-McCallum et al., 2005, Buescher et al., 2004, Abu-Shaar and Mann, 1998, Kadowaki et al., 1996, Zecca et al., 1996, Brook and Cohen, 1996, Buescher et al., 2006, Joshi et al., 2006, Leal et al., 2009, Svendsen et al., 2009, Qian et al., 2008, Beckervordersandforth et al., 2008)
Cytology
Phenotypic Data
Phenotypic Class
	viable (Buescher et al., 2006)
Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	Ecol\lacZ^H-15 Ecol\lacZ^H15-H-15 H15 (Abu-Shaar and Mann, 1998) lacZ^H-15
Name Synonym
Secondary FlyBase IDs

References ( 19 )
Research paper	Leal et al., 2009, Dev. Biol. 325(1): 138--150 Neuromancer1 and Neuromancer2 regulate cell fate specification in the developing embryonic CNS of Drosophila melanogaster. [FBrf0207072] Svendsen et al., 2009, Development 136(16): 2689--2693 The Tbx20 homologs midline and H15 specify ventral fate in the Drosophila melanogaster leg. [FBrf0208458] Beckervordersandforth et al., 2008, Mech. Dev. 125(5-6): 542--557 Subtypes of glial cells in the Drosophila embryonic ventral nerve cord as related to lineage and gene expression. [FBrf0205499] Qian et al., 2008, Proc. Natl. Acad. Sci. U.S.A. 105(50): 19833--19838 Transcription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease. [FBrf0206565] Buescher et al., 2006, Dev. Biol. 292(2): 418--429 Functions of the segment polarity genes midline and H15 in Drosophila melanogaster neurogenesis. [FBrf0190096] Joshi et al., 2006, Dev. Biol. 293(1): 64--76 Delta and Hairy establish a periodic prepattern that positions sensory bristles in Drosophila legs. [FBrf0190130] Miskolczi-McCallum et al., 2005, Dev. Biol. 278(2): 459--472 The Drosophila melanogaster T-box genes midline and H15 are conserved regulators of heart development. [FBrf0183853] Qian et al., 2005, Dev. Biol. 279(2): 509--524 Neuromancer Tbx20-related genes (H15/midline) promote cell fate specification and morphogenesis of the Drosophila heart. [FBrf0183861] Qian et al., 2005, Curr. Biol. 15(24): 2271--2278 Slit and Robo control cardiac cell polarity and morphogenesis. [FBrf0190040] Buescher et al., 2004, Curr. Biol. 14(19): 1694--1702 Drosophila T box proteins break the symmetry of hedgehog-dependent activation of wingless. [FBrf0180065] Griffin et al., 2000, Dev. Biol. 218(2): 235--247 A conserved role for H15-related T-Box transcription factors in zebrafish and Drosophila heart formation. [FBrf0125249] Svendsen et al., 2000, Development 127(19): 4083--4093 The combgap locus encodes a zinc-finger protein that regulates cubitus interruptus during limb development in Drosophila melanogaster. [FBrf0130102] Sato et al., 1999, Development 126(20): 4421--4430 Dfrizzled-3, a new Drosophila Wnt receptor, acting as an attenuator of Wingless signaling in wingless hypomorphic mutants. [FBrf0111481] Abu-Shaar and Mann, 1998, Development 125(19): 3821--3830 Generation of multiple antagonistic domains along the proximodistal axis during Drosophila leg development. [FBrf0104896] Brook and Cohen, 1996, Science 273(5280): 1373--1377 Antagonistic interactions between wingless and decapentaplegic responsible for dorsal-ventral pattern in the Drosophila Leg. [FBrf0089604] Kadowaki et al., 1996, Genes Dev. 10(24): 3116--3128 The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing. [FBrf0091095] Zecca et al., 1996, Cell 87(5): 833--844 Direct and long-range action of a wingless morphogen gradient. [FBrf0090879] Wilder and Perrimon, 1995, Development 121(2): 477--488 Dual functions of wingless in the Drosophila leg imaginal disc. [FBrf0076140] Brook et al., 1993, Development 117(4): 1287--1297 Gene expression during imaginal disc regeneration detected using enhancer-sensitive P-elements. [FBrf0064380]

Allele Ecol\lacZH15-H-15

Allele Ecol\lacZ^H15-H-15