Allele Dmel\mas^P

General Information
Symbol	Dmel\mas^P	Species	D. melanogaster
Name		FlyBase ID	FBal0044170
Feature type	allele	Associated gene	Dmel\mas

Allele class	loss of function allele
Mutagen	P-element activity
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class	loss of function allele (Murugasu-Oei et al., 1996)
Mutagen	P-element activity (Murugasu-Oei et al., 1995, Murugasu-Oei et al., 1996)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference P-element insertion is located about 500bp 3' of the mas transcription unit. (Murugasu-Oei et al., 1996) mas locus is 500bp upstream of the P{white-un1} insertion. (Murugasu-Oei et al., 1995)
Caused by insertion	P{wF}mas^P (Murugasu-Oei et al., 1995, Bloomington Drosophila Stock Center, 1999.5.18, Levis et al., 1985, Murugasu-Oei et al., 1996)
Cytology
Phenotypic Data
Phenotypic Class
	smell perception defective (Murugasu-Oei et al., 1995) taste perception defective (Murugasu-Oei et al., 1996)
Phenotype Manifest In

Detailed Description
	Statement Reference Gustatory behaviour: reduced sensitivity to sucrose. Reduced feeding is due to reduced performance of the gustatory circuits, not a disinclination to feed as demonstrated by the proboscis extension reflex. Fails to respond to low concentrations of NaCl but rejection of high concentrations of NaCl and KCl is not significantly different from wild-type; defect in the assessment of salt concentration. (Murugasu-Oei et al., 1996) Defective chemosensory perception in third instar larvae and adults. (Murugasu-Oei et al., 1995)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
Bloomington	5152 w¹¹¹⁸; P{wF}mas^P ry⁵⁰⁶/TM3, ry^RK Sb¹ Ser¹
Notes on Origin
Discoverer

Comments
	"FBti0003614 == FBti0001332 == FBti0001609 == FBti0003050 == P{wF}mas^P" was stated as revision. (Bloomington Drosophila Stock Center, 1999.5.18) Excision lines show a complete reversion to the wildtype. (Murugasu-Oei et al., 1996) A revertant caused by precise excision of the P-element has been isolated. (Murugasu-Oei et al., 1995)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	mas^P[w<up>+,ry⁺]64B</up> (Murugasu-Oei et al., 1996) mas^P unnamed (Murugasu-Oei et al., 1995)
Name Synonym
Secondary FlyBase IDs

References ( 5 )
Research paper	Murugasu-Oei et al., 1996, Mech. Dev. 57(1): 91--101 Mutations in masquerade, a novel serine-protease-like molecule, affect axonal guidance and taste behavior in Drosophila. [FBrf0089757] Murugasu-Oei et al., 1995, Genes Dev. 9(2): 139--154 Masquerade: A novel secreted serine protease-like molecule is required for somatic muscle attachment in the Drosophila embryo. [FBrf0080274] Levis et al., 1985, EMBO J. 4(13A): 3489--3499 Separable cis-acting control elements for expression of the white gene of Drosophila. [FBrf0042436]
Personal communication to FlyBase	Bloomington Drosophila Stock Center, 1999.5.18, mas<up>P</up>. mas^P. [FBrf0108509]
Abstract	Murugasu-Oei et al., 1995, Posakony, White, 1995: 122 Masquerade is required for normal chemosensory behavior and is involved in the formation of the embryonic CNS. [FBrf0084213]

Allele Dmel\masP

Allele Dmel\mas^P