FlyBase Allele Report: Dmel\phyl[4]

General Information

Symbol

Dmel\phyl⁴

Species

D. melanogaster

Name

FlyBase ID

FBal0044262

Feature type

allele

Associated gene

Dmel\phyl

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(Dickson et al., 1995)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Dickson et al., 1995)

partially lethal (with phyl²²⁴⁵)

(Pi et al., 2004)

partially lethal - majority live (with phyl¹)

(Pi et al., 2001)

partially lethal - majority live (with phyl²)

(Pi et al., 2001)

partially lethal - majority live (with phyl²²⁴⁵)

(Pi et al., 2001)

visible (with phyl¹)

(Pi et al., 2001)

visible (with phyl²)

(Pi et al., 2001)

visible (with phyl²²⁴⁵)

(Pi et al., 2001)

Phenotype Manifest In

adult abdominal segment 3 & chaeta (with phyl¹)

(Pi et al., 2001)

adult abdominal segment 3 & chaeta (with phyl²)

(Pi et al., 2001)

adult abdominal segment 3 & microchaeta (with phyl¹)

(Pi et al., 2001)

adult abdominal segment 3 & microchaeta (with phyl²)

(Pi et al., 2001)

adult abdominal segment 3 & tormogen cell | supernumerary (with phyl¹)

(Pi et al., 2001)

adult abdominal segment 3 & tormogen cell | supernumerary (with phyl²)

(Pi et al., 2001)

adult abdominal segment 3 & trichogen cell | supernumerary (with phyl¹)

(Pi et al., 2001)

adult abdominal segment 3 & trichogen cell | supernumerary (with phyl²)

(Pi et al., 2001)

adult abdominal segment 4 & chaeta (with phyl¹)

(Pi et al., 2001)

adult abdominal segment 4 & chaeta (with phyl²)

(Pi et al., 2001)

adult abdominal segment 4 & microchaeta (with phyl¹)

(Pi et al., 2001)

adult abdominal segment 4 & microchaeta (with phyl²)

(Pi et al., 2001)

adult abdominal segment 4 & tormogen cell | supernumerary (with phyl¹)

(Pi et al., 2001)

adult abdominal segment 4 & tormogen cell | supernumerary (with phyl²)

(Pi et al., 2001)

adult abdominal segment 4 & trichogen cell | supernumerary (with phyl¹)

(Pi et al., 2001)

adult abdominal segment 4 & trichogen cell | supernumerary (with phyl²)

(Pi et al., 2001)

chaeta (with phyl²²⁴⁵)

(Pi et al., 2004, Pi et al., 2001)

mesothoracic tergum & chaeta (with phyl¹)

(Pi et al., 2001)

mesothoracic tergum & chaeta (with phyl²)

(Pi et al., 2001)

mesothoracic tergum & microchaeta (with phyl¹)

(Pi et al., 2001)

mesothoracic tergum & microchaeta (with phyl²)

(Pi et al., 2001)

mesothoracic tergum & tormogen cell | supernumerary (with phyl¹)

(Pi et al., 2001)

mesothoracic tergum & tormogen cell | supernumerary (with phyl²)

(Pi et al., 2001)

mesothoracic tergum & trichogen cell | supernumerary (with phyl¹)

(Pi et al., 2001)

mesothoracic tergum & trichogen cell | supernumerary (with phyl²)

(Pi et al., 2001)

photoreceptor cell R1

(Dickson et al., 1995)

photoreceptor cell R6

(Dickson et al., 1995)

photoreceptor cell R7

(Dickson et al., 1995)

Detailed Description

Statement

Reference

phyl⁴/phyl²²⁴⁵ flies have a greatly reduced number of bristles on the notum compared to wild type.

(Pi et al., 2004)

78% of the notal microchaetae and 87% of the microchaetae on abdominal segments 3 and 4 are missing in phyl¹/phyl⁴ flies. 45% of bristles on the notum are duplicated, having 2 hairs emerging from 2 sockets or a fused socket, and 28% of bristles on the notum show other defects (including 1 hair surrounded by 2-3 sockets, and 2 socket or 4 socket clusters without shafts). 1% of bristles on abdominal segments 3 and 4 are duplicated (2 hairs/2 sockets) and 20% show other defects. The number of notal microchaetae and microchaetae on abdominal segments 3 and 4 are reduced in phyl²/phyl⁴ flies. 58% of bristles on the notum are duplicated, having 2 hairs emerging from 2 sockets or a fused socket, and 9.2% of bristles on the notum show other defects (including 1 hair surrounded by 2-3 sockets, and 2 socket or 4 socket clusters without shafts). 6.7% of bristles on abdominal segments 3 and 4 are duplicated (2 hairs/2 sockets) and 11.6% show other defects. phyl²²⁴⁵/phyl⁴ adults lack some bristles and other bristles are abnormal.

(Pi et al., 2001)

Semiviable in combination with phyl¹, phyl², phyl³, phyl⁵ and phyl⁶. Ommatidia of phyl²/phyl⁴ flies contain only 5 photoreceptor cells, an R8 and four cells of the R1-6 class. Rare ommatidia have five R1-R6 cells. Missing receptor cells are transformed to cone cells.

(Dickson et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

phyl²/phyl⁴ has visible phenotype, enhanceable by ttk[+]/ttk^1e11

(Pi et al., 2001)

phyl²/phyl⁴ has visible phenotype, enhanceable by ttk[+]/ttk^osn

(Pi et al., 2001)

Suppressed by

Statement

Reference

phyl²/phyl⁴ has visible phenotype, suppressible by ttk[+]/ttk^1e11

(Pi et al., 2001)

phyl²/phyl⁴ has visible phenotype, suppressible by ttk[+]/ttk^osn

(Pi et al., 2001)

Phenotype Manifest In

Enhanced by

Statement

Reference

phyl²/phyl⁴ has adult abdominal segment 3 & chaeta phenotype, enhanceable by ttk[+]/ttk^1e11

(Pi et al., 2001)

phyl²/phyl⁴ has adult abdominal segment 3 & trichogen cell | supernumerary phenotype, enhanceable by ttk[+]/ttk^osn

(Pi et al., 2001)

phyl²/phyl⁴ has adult abdominal segment 4 & chaeta phenotype, enhanceable by ttk[+]/ttk^osn

(Pi et al., 2001)

phyl²/phyl⁴ has adult abdominal segment 4 & tormogen cell | supernumerary phenotype, enhanceable by ttk[+]/ttk^osn

(Pi et al., 2001)

phyl²/phyl⁴ has adult abdominal segment 4 & trichogen cell | supernumerary phenotype, enhanceable by ttk[+]/ttk^osn

(Pi et al., 2001)

phyl²/phyl⁴ has adult abdominal segment 3 & tormogen cell | supernumerary phenotype, enhanceable by ttk[+]/ttk^1e11

(Pi et al., 2001)

phyl²/phyl⁴ has adult abdominal segment 3 & trichogen cell | supernumerary phenotype, enhanceable by ttk[+]/ttk^1e11

(Pi et al., 2001)

phyl²/phyl⁴ has adult abdominal segment 4 & chaeta phenotype, enhanceable by ttk[+]/ttk^1e11

(Pi et al., 2001)

phyl²/phyl⁴ has adult abdominal segment 4 & tormogen cell | supernumerary phenotype, enhanceable by ttk[+]/ttk^1e11

(Pi et al., 2001)

phyl²/phyl⁴ has adult abdominal segment 4 & trichogen cell | supernumerary phenotype, enhanceable by ttk[+]/ttk^1e11

(Pi et al., 2001)

phyl²/phyl⁴ has adult abdominal segment 3 & chaeta phenotype, enhanceable by ttk[+]/ttk^osn

(Pi et al., 2001)

phyl²/phyl⁴ has adult abdominal segment 3 & tormogen cell | supernumerary phenotype, enhanceable by ttk[+]/ttk^osn

(Pi et al., 2001)

Suppressed by

Statement

Reference

phyl²/phyl⁴ has mesothoracic tergum & tormogen cell | supernumerary phenotype, suppressible by ttk[+]/ttk^1e11

(Pi et al., 2001)

phyl²/phyl⁴ has mesothoracic tergum & tormogen cell | supernumerary phenotype, suppressible by ttk[+]/ttk^osn

(Pi et al., 2001)

phyl²/phyl⁴ has mesothoracic tergum & trichogen cell | supernumerary phenotype, suppressible by ttk[+]/ttk^1e11

(Pi et al., 2001)

phyl²/phyl⁴ has mesothoracic tergum & trichogen cell | supernumerary phenotype, suppressible by ttk[+]/ttk^osn

(Pi et al., 2001)

phyl²/phyl⁴ has adult abdominal segment 3 & microchaeta phenotype, suppressible by ttk[+]/ttk^1e11

(Pi et al., 2001)

phyl²/phyl⁴ has adult abdominal segment 3 & microchaeta phenotype, suppressible by ttk[+]/ttk^osn

(Pi et al., 2001)

phyl²/phyl⁴ has adult abdominal segment 4 & microchaeta phenotype, suppressible by ttk[+]/ttk^1e11

(Pi et al., 2001)

phyl²/phyl⁴ has adult abdominal segment 4 & microchaeta phenotype, suppressible by ttk[+]/ttk^osn

(Pi et al., 2001)

phyl²/phyl⁴ has mesothoracic tergum & chaeta phenotype, suppressible by ttk[+]/ttk^1e11

(Pi et al., 2001)

phyl²/phyl⁴ has mesothoracic tergum & chaeta phenotype, suppressible by ttk[+]/ttk^osn

(Pi et al., 2001)

phyl²/phyl⁴ has mesothoracic tergum & microchaeta phenotype, suppressible by ttk[+]/ttk^1e11

(Pi et al., 2001)

phyl²/phyl⁴ has mesothoracic tergum & microchaeta phenotype, suppressible by ttk[+]/ttk^osn

(Pi et al., 2001)

Enhancer of

Statement

Reference

phyl⁴ is an enhancer of photoreceptor cell R1 phenotype of Raf¹²

(Dickson et al., 1995)

phyl⁴ is an enhancer of photoreceptor cell R2 phenotype of Raf¹²

(Dickson et al., 1995)

phyl⁴ is an enhancer of photoreceptor cell R3 phenotype of Raf¹²

(Dickson et al., 1995)

phyl⁴ is an enhancer of photoreceptor cell R4 phenotype of Raf¹²

(Dickson et al., 1995)

phyl⁴ is an enhancer of photoreceptor cell R5 phenotype of Raf¹²

(Dickson et al., 1995)

phyl⁴ is an enhancer of photoreceptor cell R6 phenotype of Raf¹²

(Dickson et al., 1995)

phyl⁴ is an enhancer of photoreceptor cell R7 phenotype of Raf¹²

(Dickson et al., 1995)

Suppressor of

Statement

Reference

phyl⁴ is a suppressor of photoreceptor cell R7 phenotype of Raf::tor^12D.hs.sev

(Dickson et al., 1995)

Other

Statement

Reference

phyl⁴, sev^{Y1485A.W1486A.sev} has photoreceptor cell R7 phenotype

(Dickson et al., 1995)

Additional Comments

Genetic Interactions

Statement

Reference

Suppresses rough eye phenotype of phl::tor^12D.hs.sev, almost completely eliminating the extra R7 cells. Dominantly enhances the photoreceptor phenotype of phl¹² and 'sev³⁵¹'.

(Dickson et al., 1995)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescued by

phyl⁴/phyl²²⁴⁵ is partially rescued by phyl^3.4.ORF

(Pi et al., 2004)

phyl⁴/phyl²²⁴⁵ is partially rescued by phyl^3.4ΔES.ORF

(Pi et al., 2004)

phyl⁴/phyl²²⁴⁵ is partially rescued by phyl^3.4ΔE.ORF

(Pi et al., 2004)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

phyl⁴

(Shi and Noll, 2009)

Name Synonyms

Secondary FlyBase IDs

References (6)

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