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General Information
Symbol
Dmel\rlunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0044315
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    In rlunspecified mutant embryos, the initial generation of the midline glia (MG) appears to be normal (stage 13) but none survive to stage 17.

    Rolled wing edges.

    Homozygotes have rough eyes. E(S)1 has little or no effect on this phenotype in double heterozygotes.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Enhancer of
    Statement
    Reference

    rl[+]/rlunspecified is an enhancer of lethal phenotype of Raf12

    Suppressor of
    Statement
    Reference

    rl[+]/rlunspecified is a suppressor of visible phenotype of Ras85DV12.sev

    Other
    Phenotype Manifest In
    NOT Enhanced by
    Statement
    Reference

    rlunspecified has phenotype, non-enhanceable by E(S)1

    Suppressed by
    Statement
    Reference
    Enhancer of
    Statement
    Reference

    rl[+]/rlunspecified is an enhancer of eye phenotype of ksr::torΔNksr.hs.sev

    NOT Enhancer of
    Statement
    Reference

    rlunspecified is a non-enhancer of phenotype of Hsap\RALAG23V.GMR

    Suppressor of
    Statement
    Reference

    rl[+]/rlunspecified is a suppressor of eye phenotype of Ras85DV12.sev

    NOT Suppressor of
    Statement
    Reference

    rlunspecified is a non-suppressor of embryonic epidermis | dorsal phenotype of arm3

    rlunspecified is a non-suppressor of embryonic epidermis | ventral phenotype of arm3

    rlunspecified is a non-suppressor of phenotype of Hsap\RALAG23V.GMR

    Other
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    The absence of midline glia (MG) in rlunspecified embryos is suppressed by Wunspecified/Wunspecified, although the resulting cells are mislocated, lying directly below the cuticle, often in clusters of up to 20 cells. Approximately twice as many MG cells survive as in wild-type.

    The eye size of rlunspecified flies is reduced in various combinations with Su(var)2-11, Su(var)2-1213, Su(var)2-1214, Su(var)2-1216, Su(var)205unspecified or Su(var)208unspecified. The effects are generally more pronounced in females and by and large appear to be additive.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    rlunspecified
    Name Synonyms
    Secondary FlyBase IDs
      References (8)