FB2025_01 , released February 20, 2025
Allele: Dmel\wunspecified
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General Information
Symbol
Dmel\wunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0044450
Feature type
allele
Associated gene
Dmel\w
Associated Insertion(s)
Carried in Construct
Also Known As
unspecified, w-
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mutant flies have white eyes.

        (Cheli et al., 2010)

        Mutant adults are defective in aggression, as evidenced by lengthened fighting latency and reduced frequency of lunging and high-intensity fighting (holding, boxing and tussling) when two flies are placed in a small closed chamber containing a food pad in the centre. When mutant flies are paired with wild-type flies in the aggression assay, fights are initiated and won more by the wild-type flies than by the mutant flies.

        (Zhou et al., 2008)

        The spectral sensitivity curve of the whole eye in the visible range is significantly narrower than the absorption spectrum of the template visual pigments.

        (Gribakin and Ukhanov, 1990)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        Suppressor of
        Statement
        Reference

        wunspecified is a suppressor of abnormal courtship behavior | male phenotype of Blos1ex2

        (Cheli et al., 2010)
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        wunspecified/wunspecified is an enhancer of eye phenotype of Diap1RNAi.UAS.cLa, Scer\GAL4GMR.PF

        (Mallik and Lakhotia, 2009)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The increased male-to-male courtship behaviour of blos1ex2 males is suppressed by wunspecified.

        (Cheli et al., 2010)

        Scer\GAL4GMR.PF-mediated expression of thdsRNA.Scer\UAS.cLa results in a more severe eye phenotype and increased pupal lethality in a homozygous wunspecified background compared to a wunspecified/+ background.

        (Mallik and Lakhotia, 2009)

        SceD1 enhances the z-w interaction.

        (Gildea et al., 2000)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Partially complements

        wsp1

        (Lefevre and Wilkins, 1966)
        Rescued by

        wunspecified is rescued by wGMR.PT

        (Tomlinson, 2012)

        wunspecified is rescued by wUAS.cTa/Scer\GAL4GMR.PF

        (Cheli et al., 2010)
        Comments

        wGMR.PT restores all eye pigmentation in a wunspecified fly, including the subretinal pigment.

        (Tomlinson, 2012)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        The distribution of ry protein in the tissues of the adult fly is altered in this mutant.

        (Reaume et al., 1991)

        Turnover of the photoreceptor membrane in wunspecified mutant flies has been studied using electron microscopy.

        (Sapp et al., 1991)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (5)
        References (25)