Allele Dmel\RfC4^B6

General Information
Symbol	Dmel\RfC4^B6	Species	D. melanogaster
Name		FlyBase ID	FBal0045036
Feature type	allele	Associated gene	Dmel\RfC4
Also Known As	RfC40^B6

Allele class
Mutagen
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| pupal stage \| recessive (Harrison et al., 1995) lethal \| recessive (Harrison, 1999.5.12)
Phenotype Manifest In
	imaginal disc (Harrison et al., 1995)
Detailed Description
	Statement Reference Heterozygotes have wild-type eyes. (Jaffe and Jongens, 2001) Homozygous larvae have no imaginal discs, suggesting a defect in imaginal disc proliferation. (Harrison et al., 1995)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement Reference RfC40[+]/RfC4^B6 is an enhancer of eye photoreceptor cell phenotype of cutlet^rJ865a (Jaffe and Jongens, 2001) RfC40[+]/RfC4^B6 is an enhancer of ommatidium phenotype of cutlet^rJ865a (Jaffe and Jongens, 2001)
Additional Comments
Genetic Interactions
Statement Reference The cutlet^rJ865a eye phenotype is enhanced by one copy of RfC40^B6; the majority of ommatidial clusters in these flies have an abnormal number of photoreceptor cells and a large number of ommatidia are fused. (Jaffe and Jongens, 2001)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
Bloomington	5158 bw¹; RfC4^B6 st¹/TM6B, Tb¹
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	l(3)64Ai^B6 (Harrison et al., 1995) l(3)rfc40^B6 (Jaffe and Jongens, 2001) RfC4^B6 RfC40^B6 (Christensen et al., 2009.2.28, Christensen et al., 2009.2.28) rfc^40B6 (Harrison, 1999.5.12)
Name Synonym
Secondary FlyBase IDs

References ( 5 )
Research paper	Jaffe and Jongens, 2001, Dev. Biol. 230(2): 161--176 Structure-specific abnormalities associated with mutations in a DNA replication accessory factor in Drosophila. [FBrf0134541] Harrison et al., 1995, Genetics 139(4): 1701--1709 A genetic analysis of the 63E-64A genomic region of Drosophila melanogaster: Identification of mutations in a replication factor C subunit. [FBrf0080079]
Personal communication to FlyBase	Christensen et al., 2009.2.28, Isolation and characterization of Df(3L)BSC735. Isolation and characterization of Df(3L)BSC735. [FBrf0207617] Christensen et al., 2009.2.28, Isolation and characterization of Df(3L)BSC736. Isolation and characterization of Df(3L)BSC736. [FBrf0207618] Harrison, 1999.5.12, 63E-64B mutant stocks. 63E-64B mutant stocks. [FBrf0108507]

Allele Dmel\RfC4B6

Allele Dmel\RfC4^B6