FlyBase Allele Report: Dmel\aop[pok-1]

General Information

Symbol

Dmel\aop^pok-1

Species

D. melanogaster

Name

FlyBase ID

FBal0045355

Feature type

allele

Associated gene

Dmel\aop

Associated Insertion(s)

P{BmΔ-w}aop^pok-1

Carried in Construct

Also Known As

pok¹

Key Links

Genomic Maps

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Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Tei et al., 1992)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:2,174,887..2,176,283

(Tei et al., 1992)

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Cytology

Nature of the lesion

Statement

Reference

Insertion of P{BmΔ-w} within an intron.

(Tei et al., 1992)

Insertion components

P{BmΔ-w}aop^pok-1

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with aop^GT1)

(Lukacsovich et al., 2001)

lethal | recessive

(Tei et al., 1992)

short lived

(Yamamoto et al., 1996)

some die during immature adult stage | recessive

(Tei et al., 1992)

some die during larval stage

(Tei et al., 1992)

some die during pupal stage

(Tei et al., 1992)

visible

(Tei et al., 1992)

Phenotype Manifest In

ommatidium

(Tei et al., 1992)

Detailed Description

Statement

Reference

The lifespan of homozygous flies is reduced after eclosion compared to wild-type flies.

(Yamamoto et al., 1996)

Lethality occurs during larval, pupal and early adult stages. Adults have a rough eye phenotype, ommatidia contain an excess number of rhabdomeres that may have an abnormal shape. Ommatidia of double mutants with sev¹ contain a variable number of R7-like cells.

(Tei et al., 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

aop^pok-1 has short lived phenotype, suppressible by Raf[+]/Raf¹

(Yamamoto et al., 1996)

Suppressor of

Statement

Reference

aop^pok-1/aop[+] is a suppressor | partially of short lived phenotype of Raf¹

(Yamamoto et al., 1996)

Phenotype Manifest In

Suppressor of

Statement

Reference

aop^pok-1/aop[+] is a suppressor of photoreceptor cell R7 phenotype of Raf¹

(Yamamoto et al., 1996)

Other

Statement

Reference

aop^pok-1, ttk^bose1 has eye phenotype

(Yamamoto et al., 1996)

aop^pok-1, ttk[+]/ttk^bose45 has eye phenotype

(Yamamoto et al., 1996)

Additional Comments

Genetic Interactions

Statement

Reference

The longevity of aop^pok-1 homozygotes is prolonged in a phl¹ heterozygous background, although the longevity of phl¹ hemizygotes is not affected by the presence of aop^pok-1. Photoreceptor cell R7 is rescued in phl¹ hemizygotes that are also heterozygous for aop^pok-1. Does not alter the sina³ phenotype (lack of R7 photoreceptor cells) in double mutant flies. Homozygosity for ttk^bose1 or heterozygosity for ttk^bose45 reduces the size of the compound eye in the aop^pok-1 homozygous background.

(Yamamoto et al., 1996)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

aop^pok-1

aop^pok1

(Lukacsovich et al., 2001)

pok¹

(Yamamoto et al., 1996, Tei et al., 1992, Yamamoto et al., 1991)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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