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General Information
Symbol
Dmel\aoppok-1
Species
D. melanogaster
Name
FlyBase ID
FBal0045355
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
pok1
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
transposable element insertion site
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Insertion of P{BmΔ-w} within an intron.

Insertion components
P{BmΔ-w}aoppok-1
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The lifespan of homozygous flies is reduced after eclosion compared to wild-type flies.

Lethality occurs during larval, pupal and early adult stages. Adults have a rough eye phenotype, ommatidia contain an excess number of rhabdomeres that may have an abnormal shape. Ommatidia of double mutants with sev1 contain a variable number of R7-like cells.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference

aoppok-1 has short lived phenotype, suppressible by Raf[+]/Raf1

Suppressor of
Statement
Reference

aoppok-1/aop[+] is a suppressor | partially of short lived phenotype of Raf1

Phenotype Manifest In
Suppressor of
Statement
Reference

aoppok-1/aop[+] is a suppressor of photoreceptor cell R7 phenotype of Raf1

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The longevity of aoppok-1 homozygotes is prolonged in a phl1 heterozygous background, although the longevity of phl1 hemizygotes is not affected by the presence of aoppok-1. Photoreceptor cell R7 is rescued in phl1 hemizygotes that are also heterozygous for aoppok-1. Does not alter the sina3 phenotype (lack of R7 photoreceptor cells) in double mutant flies. Homozygosity for ttkbose1 or heterozygosity for ttkbose45 reduces the size of the compound eye in the aoppok-1 homozygous background.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (4)