FlyBase Allele Report: Dmel\elav[C155]

General Information

Symbol

Dmel\elav^C155

Species

D. melanogaster

Name

FlyBase ID

FBal0045582

Feature type

allele

Associated gene

Dmel\elav

Associated Insertion(s)

P{GawB}elav^C155

Carried in Construct

Also Known As

elav-Gal4, elav^C155-GAL4, c155-Gal4, elav-GAL4^c155, C155, elavGal4, GAL4-C155, elav^c155GAL4, P{GawB}elav^c155, elav-GAL4 (C155)

Genomic Maps

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Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Rebay and Rubin, 1995, Lin and Goodman, 1994)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

transposable element insertion site

X:523,350..523,350 [-]X:523,343..523,350 [-]

(Ogienko et al., 2020, Mallik and Lakhotia, 2011, Zeng et al., 2010, Dickman, 2006, Rebay and Rubin, 1995, Lin and Goodman, 1994, FBrf0086269)

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Cytology

Nature of the lesion

Statement

Reference

P{GawB} insertion in the promoter region of elav. The orientation of the GAL4 coding sequence within the P{GawB} element is the same as the direction of elav transcription.

(Ogienko et al., 2020)

Insertion components

P{GawB}elav^C155

Product class / Tool use(s)

Encoded product / tool

enhancer trap

GAL4

binary expression system - driver

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | progressive

(Deleault et al., 2003)

partially lethal - majority live | dominant

(Mallik and Lakhotia, 2011)

some die during P-stage | dominant

(Mallik and Lakhotia, 2011)

Phenotype Manifest In

Detailed Description

Statement

Reference

Presence of a single copy of Scer\GAL4^elav-C155 in the absence of any responder transgene causes approximately four percent of animals to die as pupae.

(Mallik and Lakhotia, 2011)

Flies homozygous for elav^C155 show a decline in climbing ability with advancing age from week 1 to week 3.

(Deleault et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

elav^C155 has some die during P-stage | dominant phenotype, non-enhanceable by Scer\GAL4^elav-C155/lncRNA:Hsrω^EP93D/ lncRNA:Hsromega [+]