FB2025_01 , released February 20, 2025
Allele: Dmel\eveunspecified
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General Information
Symbol
Dmel\eveunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0045611
Feature type
allele
Associated gene
Dmel\eve
Associated Insertion(s)
Carried in Construct
Also Known As
unspecified
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        In eveunspecified mosaic mutants, dorsal motor-axon projections show multiple defects including abnormally short projections (31%), bifurcations (20%), and inappropriate crossing of segment boundaries (20%).

        (Labrador et al., 2005)

        Mutant embryos lack cephalic furrows.

        (Blankenship and Wieschaus, 2001)

        Midgut constrictions do not form and there is some degeneration of the midgut epithelium in homozygous embryos.

        (Harbecke and Lengyel, 1995)

        In Ubxhs.PG embryos that are homozygous for eveunspecified the C2 belt is missing.

        (Gonzalez-Reyes and Morata, 1991)

        Embryos show pair rule segmentation defects.

        (Tearle and Nusslein-Volhard, 1987)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Suppressed by
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Expression of unc-5Scer\UAS.T:Ivir\HA1,T:wg in eveunspecified aCC and RP2 cells, driven by Scer\GAL4eve.RN2, results in significant rescue of dorsal motor-axon guidance.

        (Labrador et al., 2005)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        eveunspecified
        unspecified
        (Harbecke and Lengyel, 1995, Gonzalez-Reyes and Morata, 1991)
        Name Synonyms
        Secondary FlyBase IDs
          References (10)