Allele Dmel\gro^BFP2

General Information
Symbol	Dmel\gro^BFP2	Species	D. melanogaster
Name		FlyBase ID	FBal0045820
Feature type	allele	Associated gene	Dmel\gro

Allele class
Mutagen	ethyl methanesulfonate
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	ethyl methanesulfonate (Fischer-Vize et al., 1992)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	female sterile \| partially (Fischer-Vize et al., 1992) male sterile \| partially (Fischer-Vize et al., 1992) viable \| recessive (Fischer-Vize et al., 1992) visible \| recessive (Fischer-Vize et al., 1992)
Phenotype Manifest In
	ommatidium (Fischer-Vize et al., 1992)
Detailed Description
	Statement Reference No effect on the faf eye phenotype. (Huang and Fischer-Vize, 1996) Mutation has no effect on rho^hs.sev rough eye phenotype. (Freeman, 1994) Flies are only marginally fertile, and their wings are broader and slightly held out. The eyes are slightly bulged and have some bristle spacing defects. Approximately two-thirds of the ommatidia have one, two or three additional outer photoreceptor cells, and the orientation of the ommatidia is irregular. gro^BFP2/gro¹ transheterozygotes have wild-type eyes. In mosaic animals, approximately 17% of ommatidia containing both wild-type and gro^BFP2 cells are "rescued" to wild-type. Phenotypically mutant ommatidia in which the cells are genotypically wild-type are also seen at the edge of mutant clones. (Fischer-Vize et al., 1992)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Other
Statement Reference E(spl)m8-HLH^unspecified, gro^BFP2 has eye phenotype (Fischer-Vize et al., 1992, Fischer-Vize et al., 1992)
Additional Comments
Genetic Interactions
Statement Reference Heterozygotes for E(spl) that are also heterozygous for gro^BFP2 have eye defects that are similar but not identical to gro^BFP2 homozygotes. (Fischer-Vize et al., 1992)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescued by	gro^BFP2 is rescued by gro^+t10.4 (Fischer-Vize et al., 1992)
Comments	E(spl)^+t10.4 rescues the homozygous gro^BFP2 phenotype. (Fischer-Vize et al., 1992)
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	gro^BFP2 has been characterised. (Fischer-Vize et al., 1992)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	gro^BFP2 gro^FP2 (Freeman, 1994)
Name Synonym
Secondary FlyBase IDs

References ( 4 )
Research paper	Huang and Fischer-Vize, 1996, Development 122(10): 3207--3216 Undifferentiated cells in the developing Drosophila eye influence facet assembly and require the Fat facets ubiquitin-specific protease. [FBrf0090618] Freeman, 1994, Mech. Dev. 48(1): 25--33 The spitz gene is required for photoreceptor determination in the Drosophila eye where it interacts with the EGF receptor. [FBrf0078442] Fischer-Vize et al., 1992, Development 115: 89--101 A unique mutation in the Enhancer of split gene complex affects the fates of the mystery cells in the developing Drosophila eye. [FBrf0055903]
Review	Venkatesh, 1993, J. Neurobiol. 24(6): 740--756 Neuronal development in the Drosophila retina. [FBrf0058901]

Allele Dmel\groBFP2

Allele Dmel\gro^BFP2