Allele Dmel\l(3)87Df^7.2

General Information
Symbol	Dmel\l(3)87Df^7.2	Species	D. melanogaster
Name		FlyBase ID	FBal0046075
Feature type	allele	Associated gene	Dmel\l(3)87Df

Allele class
Mutagen	in vitro construct - genomic fragment
Recent Updates
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FB2013_03	Stocks FBst0043637
FB2013_02
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Nature of the Allele
Allele class
Mutagen	in vitro construct - genomic fragment (Horowitz and Berg, 1995)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: Portion of l(3)87Df containing an intron of 70 nucleotides, the splice acceptor site and the remaining coding sequence and transcription termination sequences. (Horowitz and Berg, 1995)
Carried in construct	P{PZ} (Horowitz and Berg, 1995)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 560 )
Bloomington	4159 ry⁵⁰⁶ P{PZ}900 5374 P{PZ}ap^rK568/CyO 5530 ry⁵⁰⁶ P{PZ}hh^P30 25079 P{PZ}dpr¹; ry⁵⁰⁶ 9093 P{PZ}Gli^rL82; ry⁵⁰⁶ 684 ry⁵⁰⁶ P{PZ}fru³/MKRS 11611 ry⁵⁰⁶ P{PZ}MI02⁰³⁸⁴⁷ 11743 ry⁵⁰⁶ P{PZ}btsz¹⁰⁴¹⁸ 12047 P{PZ}dac^P/CyO; ry⁵⁰⁶ 12171 cn¹ P{PZ}cuc¹⁰⁶⁰⁷/CyO 12063 P{PZ}sls^rL182/TM3, Sb¹ 12285 P{PZ}Aph-4⁰⁷⁰²⁸, ry⁵⁰⁶
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Notes on Origin
Discoverer

Comments
	P{PZ} insertion within an psq intron causes an aberrant splicing and transcription termination event due to l(3)87Df sequences flanking the HindIII ry fragment within the P{PZ} element. The aberrant splicing event is entirely responsible for the mutant phenotype. (Horowitz and Berg, 1995)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	l(3)87Df^7.2
Name Synonym
Secondary FlyBase IDs

References ( 6 )
Research paper	Horowitz and Berg, 1996, Development 122(6): 1859--1871 The Drosophila pipsqueak gene encodes a nuclear BTB-domain-containing protein required early in oogenesis. [FBrf0088214] Horowitz and Berg, 1995, Genetics 139(1): 327--335 Aberrant splicing and transcription termination caused by P element insertion into the intron of a Drosophila gene. [FBrf0078675] Murphy and Karpen, 1995, Cell 82(4): 599--609 Localization of centromere function in a Drosophila minichromosome. [FBrf0083324] Spradling, 1993, Cold Spring Harbor Symp. Quant. Biol. 58: 585--596 Position effect variegation and genomic instability. [FBrf0074515] Tower et al., 1993, Genetics 133(2): 347--359 Preferential transposition of Drosophila P-elements to nearby chromosomal sites. [FBrf0058564] Zhang and Spradling, 1993, Genetics 133(2): 361--373 Efficient and dispersed local P-element transposition from Drosophila females. [FBrf0058565]

Allele Dmel\l(3)87Df7.2

Allele Dmel\l(3)87Df^7.2