|Feature type||allele||Associated gene||Dmel\mod(mdg4)|
|Allele class||amorphic allele - genetic evidence|
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|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
Mutation is in the 67.2 exon.
Amino acid replacement: ?578@.
Nucleotide substitution: at position 137511 of AE003734.
|Phenotype Manifest In|
mod(mdg4)[+]/mod(mdg4)T6 is an enhancer of visible | dominant | homeotic phenotype of ash1[+]/ash117, trxB11
mod(mdg4)[+]/mod(mdg4)T6 is an enhancer of visible | dominant | homeotic phenotype of brm[+]/brm2, trxE2
|Phenotype Manifest In|
y mod(mdg4)[T6] double mutant flies have a dappled abdomen with pale bristles. mod(mdg4)[T6] suppresses the "cut" wing phenotype observed in ct mutant flies, and the wing margins are fully restored in these animals. The "cut" wing phenotype observed in ct[K] mutant animals is suppressed in a mod(mdg4)[T6] mutant background.
Body colour: y2 ; mod(mdg4)T6/mod(mdg4)T16 flies have a y- phenotype (yellow bristles, wings and bodies).
mod(mdg4)T6 trxB11 double heterozygotes show a transformation of haltere to wing in 0.3% of cases. Increases the frequency of homeotic transformations seen in trxB11 ash117 double heterozygotes. Increases the frequency of homeotic transformations seen in trxE2 brm2 double heterozygotes.
|Complementation & Rescue Data|
|Fails to complement|
mod(mdg4)T6 fully complements mod(mdg4)Z3-3401, mod(mdg4)Z3-5578 and mod(mdg4)Z3-3298 with respect to X-Y chromosome nondisjunction in male meiosis. mod(mdg4)T6/Df(3R)GC14 females do not show increased X chromosome nondisjunction compared to controls and the frequency of recombination in large intervals on the second and third chromosomes in the mutant females is normal.
|Stocks ( 0 )|
|Notes on Origin|
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 3 )|
|Secondary FlyBase IDs|
|References ( 11 )|