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General Information
Symbol
Dmel\oskM139L
Species
D. melanogaster
Name
FlyBase ID
FBal0046233
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Mutation in the second start codon.

Construct: Nucleotide substitution: A626C. Amino acid replacement: M139L.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

oskM139L; osk1/Df(3R)p-XT103 embryos express only the long osk isoform. These embryos show patterning defects and a "twisted phenotype". Muscle development is defective with embryos showing a dramatic reduction in the number of muscles, a large number of unfused myoblasts and defects in muscle morphology.

No embryos expressing oskM139L in a oskA87/Df(3R)p-XT103 background hatch. 100% of these embryos have posterior cuticle defects. 84-91% of embryos expressing both oskM1R and oskM139L in a oskA87/Df(3R)p-XT103 background hatch. The unhatched embryos develop cuticles without obvious patterning defects. 100% of females derived from the embryos that hatch have wild-type ovaries.

osk1/Df(3R)p-XT103 embryos carrying P{oskM139L} do not hatch, embryos typically develop 2 to 4 abdominal segments. The few adults that emerge are sterile.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Produces only long osk protein.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (6)