Allele Dmel\pk^pk-sple-26

General Information
Symbol	Dmel\pk^pk-sple-26	Species	D. melanogaster
Name		FlyBase ID	FBal0046284
Feature type	allele	Associated gene	Dmel\pk
Also Known As	pk-sple²⁶

Allele class
Mutagen	X ray
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	X ray (Gubb et al., 1999)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	In(2LR)O (Gubb et al., 1999)
Nature of the lesion	Statement Reference Lesion present between 50.3 and 53.5kb downstream of zero (zero being 973bp proximal to the pk transcription start site.). (Gubb et al., 1999)
Caused by aberration	Tp(2;2)pk-sple²⁶ (Gubb et al., 1999, Roote, 1996.3.6)
Carried on aberration	CyO-G (FlyBase Curators, 2006-, Lindsley and Zimm, 1992, Gubb, 1998.2.25)
Cytology
Phenotypic Data
Phenotypic Class
	planar polarity defective (Gubb et al., 1999) visible \| recessive (Gubb, 1998.2.25)
Phenotype Manifest In
	abdomen (Gubb et al., 1999) eye (Gubb et al., 1999) leg (Gubb et al., 1999) scutum (Gubb et al., 1999) wing (Gubb et al., 1999)
Detailed Description
	Statement Reference Causes no embryonic phenotype even when homozygous mutant embryos develop from homozygous mutant mothers. Has a weak polarity phenotype in the wing, notum, abdomen, eye and legs. Denticle belt morphology and denticle orientation remains wild-type. (Gubb et al., 1999)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference pk^pk-sple-26 is an enhancer of cell polarity defective phenotype of Scer\GAL4^hs.2sev, Vang^Scer\UAS.cWa (Jenny et al., 2003)
Phenotype Manifest In
Enhancer of
Statement Reference pk^pk-sple-26 is an enhancer of ommatidium phenotype of Scer\GAL4^hs.2sev, Vang^Scer\UAS.cWa (Jenny et al., 2003)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 5 )
Bloomington	8889 Df(2R)sple-D1, b¹ cn¹/CyO, Tp(2;2)pk-sple²⁶, pk^pk-sple-26 4130 In(2R)DX8, Dscam¹⁷ cn¹ bw¹ sp¹/CyO, Tp(2;2)pk-sple²⁶, pk^pk-sple-26 4118 Tp(2;3)DX11, l(2)43Bb³ cn¹ bw¹ sp¹/CyO, Tp(2;2)pk-sple²⁶, pk^pk-sple-26 5887 Tp(2;2)pk-sple²², b¹ l(2)42Eb^pk-sple-22 pk^pk-sple-22 cn¹/CyO, Tp(2;2)pk-sple²⁶, pk^pk-sple-26
Kyoto	107597 In(2R)DX8, Dscam¹⁷ cn¹ bw¹ sp¹/CyO, Tp(2;2)pk-sple²⁶, pk^pk-sple-26
Notes on Origin
Discoverer	D. Coulson.

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	pk²⁶ pk^pk-sple-26 pk-sple²⁶ (Jenny et al., 2003, Roote, 1996.3.6) pk-sple^81h (Roote, 1996.3.6, ) sple²⁶
Name Synonym
Secondary FlyBase IDs
	FBal0046519
References ( 6 )
Research paper	Jenny et al., 2003, EMBO J. 22(17): 4409--4420 Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signaling. [FBrf0162094] Gubb et al., 1999, Genes Dev. 13(17): 2315--2327 The balance between isoforms of the prickle LIM domain protein is critical for planar polarity in Drosophila imaginal discs. [FBrf0111378]
Personal communication to FlyBase	Gubb, 1998.2.25, pk update. pk update. [FBrf0100820] Roote, 1996.3.6, Tp pk. Tp pk. [FBrf0086265]
FlyBase analysis	FlyBase Curators, 2006-, Balancer summary information. Balancer summary information. [FBrf0189689]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]

Allele Dmel\pkpk-sple-26

Allele Dmel\pk^pk-sple-26