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General Information
Symbol
Dmel\rost30A
Species
D. melanogaster
Name
FlyBase ID
FBal0046383
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Insertion of a P{hsneo} element in the 5' untranslated region, 248bp upstream of the putative ATG start codon.

P{hsneo} insertion within 5' upstream sequences.

Insertion components
P{hsneo}rost30A
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Muscle specific phenotype.

Dorsal vessel and visceral mesoderm is unaffected in embryos homozygous for the "rost30A" chromosome (carrying both rost30A and sns43-49 but major distortions occur in somatic mesoderm. Late stages of embryonic development show many unfused myoblasts. First distortions are visible during germ-band retraction. Unfused myoblasts are often arranged in specific locations where in the wild type ventral, pleural and longitudinal muscles form.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Separable from: sns43-49. The "rost30A" chromosome contains mutations in two genes that affect muscle fusion. One mutation is in rost (rost30A) and the other is sns43-49.

Comments
Comments

Excision of the P{hsneo} element reverts the lethality of rost30A.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
rost30A
rostP20
Name Synonyms
Secondary FlyBase IDs
    References (6)