Allele Dmel\y^2PR2

General Information
Symbol	Dmel\y^2PR2	Species	D. melanogaster
Name		FlyBase ID	FBal0046853
Feature type	allele	Associated gene	Dmel\y

Map ( GBrowse )	Untitled Document
Allele class
Mutagen	spontaneous, hobo activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	hobo activity (Harrison et al., 1989, Georgiev and Corces, 1995, Soldatov et al., 1999) spontaneous (Harrison et al., 1989)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site X:249,853..249,856 (Georgiev and Corces, 1995, Harrison et al., 1989)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	y² (Harrison et al., 1989, Georgiev and Corces, 1995)
Nature of the lesion	Statement Reference hobo insertion within the region of 12 su(Hw) binding sites of gypsy. (Georgiev and Corces, 1995) Insertion of a 1.8kb deleted hobo into the 5' region of the gypsy element, 813bp from the beginning of the gypsy element. (Harrison et al., 1989)
Caused by insertion	gypsy{}y² (Georgiev and Corces, 1995, Harrison et al., 1989) H{}y^2PR2 (Soldatov et al., 1999, Georgiev and Corces, 1995, Harrison et al., 1989)
Cytology
Phenotypic Data
Phenotypic Class
	body color defective (Soldatov et al., 1999)
Phenotype Manifest In
	adult (Soldatov et al., 1999) cuticle (Georgiev and Kozycina, 1996) wing (Soldatov et al., 1999, Georgiev and Kozycina, 1996)
Detailed Description
	Statement Reference Body colour: mutant flies have reduced pigmentation in the body and wings, but wild-type pigmentation in the thoracic, leg and abdominal bristles. (Soldatov et al., 1999)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement Reference y^2PR2 has body color defective phenotype, enhanceable by e(y)1¹ (Soldatov et al., 1999)
Phenotype Manifest In
Enhanced by
Statement Reference y^2PR2 has cuticle phenotype, enhanceable by mod(mdg4)^ul (Georgiev and Kozycina, 1996) y^2PR2 has macrochaeta & abdomen phenotype, enhanceable by mod(mdg4)^ul (Georgiev and Kozycina, 1996) y^2PR2 has macrochaeta & leg phenotype, enhanceable by mod(mdg4)^ul (Georgiev and Kozycina, 1996) y^2PR2 has macrochaeta & thorax phenotype, enhanceable by mod(mdg4)^ul (Georgiev and Kozycina, 1996) y^2PR2 has macrochaeta & wing phenotype, enhanceable by mod(mdg4)^ul (Georgiev and Kozycina, 1996) y^2PR2 has wing phenotype, enhanceable by mod(mdg4)^ul (Georgiev and Kozycina, 1996)
Other
Statement Reference e(y)1¹, y^2PR2 has adult thorax & macrochaeta phenotype (Soldatov et al., 1999) e(y)1¹, y^2PR2 has leg & external sensory organ phenotype (Soldatov et al., 1999)
Additional Comments
Genetic Interactions
Statement Reference Pigmentation of the thoracic and leg bristles is reduced in combination with e(y)1¹. (Soldatov et al., 1999)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Complements	y² (Georgiev and Kozycina, 1996)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer
	Revertant \partial. (Harrison et al., 1989)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	y^2PR2
Name Synonym
Secondary FlyBase IDs

References ( 4 )
Research paper	Soldatov et al., 1999, Mol. Cell. Biol. 19(5): 3769--3778 TAFII40 protein is encoded by the e(y)1 gene: biological consequences of mutations. [FBrf0108279] Georgiev and Kozycina, 1996, Genetics 142(2): 425--436 Interaction between mutations in the suppressor of Hairy wing and modifier of mgd4 genes of Drosophila melanogaster affecting the phenotype of gypsy-induced mutations. [FBrf0086415] Georgiev and Corces, 1995, Proc. Natl. Acad. Sci. U.S.A. 92(11): 5184--5188 The su(Hw) protein bound to gypsy sequences in one chromosome can repress enhancer-promoter interactions in the paired gene located in the other homolog. [FBrf0082023] Harrison et al., 1989, Dev. Genet. 10: 239--248 The gypsy retrotransposon of Drosophila melanogaster: mechanisms of mutagenesis and interaction with the suppressor of Hairy-wing locus. [FBrf0049522]

Allele Dmel\y2PR2

Allele Dmel\y^2PR2