FB2025_01 , released February 20, 2025
Allele: Scer\GAL4C41
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General Information
Symbol
Scer\GAL4C41
Species
S. cerevisiae
Name
FlyBase ID
FBal0047060
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{GawB}C41
Carried in Construct
Also Known As
c41
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Yeh et al., 1995)
Delta2-3 transposase
(Gustafson and Boulianne, 1996)
Progenitor genotype
Associated Insertion(s)
P{GawB}C41
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{GawB}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      No Assay Recorded
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage
      presumptive embryonic/larval peripheral nervous system
      (Yeh et al., 1995)
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      late embryonic stage
      larval peripheral nervous system | restricted
      (Gustafson and Boulianne, 1996)
      third instar larval stage
      distal rostral sensillum | precursor
      (Gustafson and Boulianne, 1996)
      postoccipital trichoid sensillum | precursor
      (Gustafson and Boulianne, 1996)
      proximal rostral sensillum | precursor
      (Gustafson and Boulianne, 1996)
      eye disc | restricted
      (Gustafson and Boulianne, 1996)
      wing sensillum | precursor
      (Gustafson and Boulianne, 1996)
      postgenal trichoid sensillum | precursor
      (Gustafson and Boulianne, 1996)
      wing disc | restricted
      (Gustafson and Boulianne, 1996)
      photoreceptor neuron | precursor
      (Gustafson and Boulianne, 1996)
      antennal disc | restricted
      (Gustafson and Boulianne, 1996)
      scutellum | precursor
      (Gustafson and Boulianne, 1996)
      adult stage
      ellipsoid body
      (Sakai and Kitamoto, 2006)
      adult mushroom body | faint | restricted
      (Sakai and Kitamoto, 2006)
      adult gnathal ganglion | restricted
      (Sakai and Kitamoto, 2006)
      adult pars intercerebralis | restricted
      (Sakai and Kitamoto, 2006)
      Additional Information
      Statement
      Reference

      ScerGAL4C41 drives expression in the ellipsoid body, faintly in some mushroom body neurons, in the pars intercerebralis and in some neurons of the subesophageal ganglion.

      (Sakai and Kitamoto, 2006)

      In late embryo, expression in subset of cells in the PNS. In third instar larva antennal disc, expression in precursors of the postgenal sensilla, proximal and distal rostral sensilla, and the postoccipital sensilla; in the eye disc, expression in the presumptive photoreceptor cells. In third instar wing disc, expressed in presumptive scutellum, in precursors of the dorsal sensilla campaniformia and the ventral sensilla campaniformia.

      (Gustafson and Boulianne, 1996)

      Expressed in most, but not all cells of the peripheral nervous system.

      (Yeh et al., 1995)
       
      Marker for
      larval central brain
      (Kucherenko et al., 2016)
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using shi1.UAS at 32[o]C) of Scer\GAL4C41 cells in adults does not affect startle-induced climbing behavior, compared to controls.

      Thermogenetic activation (using TrpA1UAS.(B).cKa at 32[o]C) of Scer\GAL4C41 cells in adults does not affect startle-induced climbing behavior, compared to controls.

      (Sun et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      GAL4C41
      Scer\GAL4C41
      Name Synonyms
      Secondary FlyBase IDs
        References (7)