FlyBase Allele Report: Dmel\CycB[Δ90]

General Information

Symbol

Dmel\CycB^Δ90

Species

D. melanogaster

Name

FlyBase ID

FBal0048169

Feature type

allele

Associated gene

Dmel\CycB

Associated Insertion(s)

Carried in Construct

P{Hs-SUΔ90cyclinB}

Key Links

Transgenic product class

inframe_deletion

(Sigrist et al., 1995)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

inframe_deletion

(Sigrist et al., 1995)

Mutagen

in vitro construct

(Sigrist et al., 1995)

Progenitor genotype

CycB^hs.PK

(Sigrist et al., 1995)

Carried in construct

P{Hs-SUΔ90cyclinB}

Cytology

Description

Deletion of the N-terminal 90 amino acids.

(Sigrist et al., 1995)

Allele components

Component

Use(s)

Regulatory region(s)

Hsp70

Encoded product / tool

CycB

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

CycB^Δ90, CycB3^Δ, Cdk1^hs.PS is a non-suppressor of abnormal mitotic cell cycle | embryonic stage phenotype of CycA^C8LR1

(Reber et al., 2006)

CycB^Δ90, CycB3^Δ, stg^hs.PE2 is a non-suppressor of abnormal mitotic cell cycle | embryonic stage phenotype of CycA^C8LR1

(Reber et al., 2006)

Other

Statement

Reference

Cdk1^AF.hs, CycA^C8LR1, CycB3^Δ, CycB^Δ90 has abnormal mitotic cell cycle | embryonic stage phenotype

(Reber et al., 2006)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

CycB^Δ90, CycB3^Δ, Cdk1^hs.PS is a non-suppressor of embryonic epidermis phenotype of CycA^C8LR1

(Reber et al., 2006)

CycB^Δ90, CycB3^Δ, stg^hs.PE2 is a non-suppressor of embryonic epidermis phenotype of CycA^C8LR1

(Reber et al., 2006)

Other

Statement

Reference

Cdk1^AF.hs, CycA^C8LR1, CycB3^Δ, CycB^Δ90 has embryonic epidermis phenotype

(Reber et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

Coexpression of three transgenes, cdc2^AF.hs, CycB^Δ90, and CycB3^Δ, restores the entry of epidermal cells in CycA^C8LR1 embryos into mitosis 16. After entry into mitosis, the epidermal cells are unable to complete this division.

Coexpression of the transgenes, cdc2^hs.PS, CycB^Δ90, and CycB3^Δ, does not restore the entry of epidermal cells in CycA^C8LR1 embryos into mitosis 16. Likewise, coexpression of stg^hs.PE2, CycB^Δ90 and CycB3^Δ does not suppress the phenotype.

(Reber et al., 2006)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

CycB^Δ90

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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