FlyBase Allele Report: Dmel\Delta[UAS.cDa]

(Even et al., 2019, Vicente et al., 2018, Wong et al., 2014, De Keersmaecker et al., 2013, Bossuyt et al., 2009, Lee et al., 2009, Ferres-Marco et al., 2006, Dominguez et al., 2004, Dominguez and de Celis, 1998)

eye, with Scer\GAL4^ey.PU

(Barrios et al., 2015, Zhai et al., 2012)

eye disc, with Scer\GAL4^ey.PH

(Vicente et al., 2018)

eye disc | third instar larval stage, with Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

eye photoreceptor cell, with Scer\GAL4^hs.2sev

(Strutt et al., 2002)

femur & joint, with Scer\GAL4^klu-G410

(Bishop et al., 1999)

filamentous actin & dorsal mesothoracic disc, with Scer\GAL4^Act5C.PI

(Major and Irvine, 2005)

genitalia | heat sensitive, with Scer\GAL4^ptc-559.1

(Doherty et al., 1996)

germarium cap cell | ectopic | heat sensitive, with Scer\GAL4^hs.PB

(Song et al., 2007)

germarium cap cell | increased number | heat sensitive, with Scer\GAL4^hs.PB

(Song et al., 2007)

head | heat sensitive, with Scer\GAL4^ptc-559.1

(Doherty et al., 1996)

interommatidial bristle | increased number, with Scer\GAL4^GMR.PF

(Mishra-Gorur et al., 2002)

leg, with Scer\GAL4^Act5C.PI

(Rauskolb and Irvine, 1999)

leg | distal, with Scer\GAL4^ap-md544

(Mishra et al., 2001)

leg | distal, with Scer\GAL4^Dll-md23

(Mishra et al., 2001)

leg | heat sensitive, with Scer\GAL4^ptc-559.1

(Doherty et al., 1996)

leg joint, with Scer\GAL4^Act5C.PI

(Rauskolb and Irvine, 1999)

leg joint, with Scer\GAL4^ap-md544

(Mishra et al., 2001)

lens, with Scer\GAL4^GMR.PF

(Mishra-Gorur et al., 2002)

mesothoracic postnotum | heat sensitive, with Scer\GAL4^ptc-559.1

(Doherty et al., 1996)

metatarsus, with Scer\GAL4^dpp.blk1

(de Celis et al., 1998)

microchaeta | ectopic, with Scer\GAL4^Eq

(Ahmed et al., 2003)

ommatidium, with Scer\GAL4^hs.2sev

(Strutt et al., 2002)

oocyte & pericentriolar material, with Scer\GAL4^hs.PB

(Larkin et al., 1999)

oocyte nucleus, with Scer\GAL4¹⁰⁹

(Larkin et al., 1999)

photoreceptor neuron | increased number, with Scer\GAL4^GMR.PF

(Mishra-Gorur et al., 2002)

pigment cell | increased number, with Scer\GAL4^GMR.PF

(Mishra-Gorur et al., 2002)

pretarsus, with Scer\GAL4^ap-md544

(Mishra et al., 2001)

pronotum | heat sensitive, with Scer\GAL4^ptc-559.1

(Doherty et al., 1996)

scutum | heat sensitive, with Scer\GAL4^ptc-559.1

(Doherty et al., 1996)

sense organ, with Scer\GAL4^sca-109-68

(Doherty et al., 1997)

sense organ, with Scer\GAL4^sca-537.4

(Doherty et al., 1997)

stalk follicle cell, with Scer\GAL4^hs.PB

(Larkin et al., 1999)

tarsal segment 2, with Scer\GAL4^dpp.blk1

(de Celis et al., 1998)

tarsal segment 4, with Scer\GAL4^ap-md544

(Mishra et al., 2001)

tarsal segment, with Scer\GAL4^ap-md544

(Bishop et al., 1999)

tarsal segment, with Scer\GAL4^dpp.blk1

(de Celis et al., 1998)

tarsal segment, with Scer\GAL4^klu-G410

(Bishop et al., 1999)

tarsal segment & joint, with Scer\GAL4^klu-G410

(Bishop et al., 1999)

tibia & joint, with Scer\GAL4^klu-G410

(Bishop et al., 1999)

tracheal branch primordium, with Scer\GAL4^btl.PS

(Llimargas, 1999)

wing, with Scer\GAL4^A9

(Mishra-Gorur et al., 2002)

wing, with Scer\GAL4^vg.int2.1

(Mishra-Gorur et al., 2002)

wing | dorsal, with Scer\GAL4^ptc-559.1

(Panin et al., 1997)

wing | dorsal, with Scer\GAL4^Ubx.PdC

(de Celis and Bray, 1997)

wing | heat sensitive, with Scer\GAL4^ptc-559.1

(Doherty et al., 1996)

wing disc, with Scer\GAL4^dpp.blk1

(Go et al., 1998)

wing disc, with Scer\GAL4^ptc-559.1

(Go et al., 1998)

wing disc | dorsal, with Scer\GAL4^dpp.blk1

(Lai et al., 2005)

wing vein, with Scer\GAL4^Ubx.PdC

(de Celis and Bray, 1997)

Detailed Description

Statement

Reference

Expression of Dl^UAS.cDa under the control of Scer\GAL4^ey.PH leads to eye tumor and metastasis.

(Even et al., 2019)

The expression of Dl^UAS.cDa under the control of Scer\GAL4^ey.PH induces an increase in eye size, but only a low frequency of tumors. The eye disc is exhibits an increase in cell divisions (BrdU labelling and pH3 immunostaining), as compared to controls.

(Vicente et al., 2018)

Expression of Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PU results in slightly enlarged eyes.

(Barrios et al., 2015)

Over-expression of Dl, through expression of Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PH causes slightly enlarged eyes.

(Wong et al., 2014)

Scer\GAL4^ey.PH Dl^Scer\UAS.cDa eyes are large but rarely develop tumours.

(De Keersmaecker et al., 2013)

Flies expressing Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PU have mildly overgrown eyes and never display eye tumours or invasive tumours.

(Zhai et al., 2012)

Scer\GAL4^ey.PH-mediated expression of Dl^Scer\UAS.cDa results in an increase in proliferation, leading to a slight overgrowth of the eye, but no tumors.

Scer\GAL4^ey.PH-mediated expression of Dl^Scer\UAS.cDa in third instar eye discs results in modest increased cell proliferation (as measured by phospho-histoneH3) posterior to the second mitotic wave.

Scer\GAL4^ey.PH Dl^Scer\UAS.cDa third instar eye discs show a wild type regular and stereotypical differentiation and epithelial organization of the developing retina, although the discs are clearly larger.

(Bossuyt et al., 2009)

Expression of Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PH results in an overproliferation phenotype in the eye.

(Lee et al., 2009)

Expression of Dl^Scer\UAS.cDa under the control of Scer\GAL4^sca-537.4 is lethal at 29[o]C. No salivary gland defects are seen when flies are raised at room temperature and shifted to 29[o]C at the second instar larval stage.

(Commisso and Boulianne, 2008)

Expression of Dl^Scer\UAS.cDa under the control of Scer\GAL4^hs.PB using heat shock during the second larval instar or after the mid-pupal stage does not result in an increase in cap cell number at the normal location in the female germarium and does not induce ectopic cap cell formation.

Expression of Dl^Scer\UAS.cDa under the control of Scer\GAL4^hs.PB using heat shock during during the third instar or during the early pupal stage results in an increase in the number of cap cells at the tip of some female germaria. In addition, about 10% of the germaria have ectopic cap cells.

(Song et al., 2007)

Expression of Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PH results in a large eye phenotype.

(Ferres-Marco et al., 2006)

Misexpression of Dl^Scer\UAS.cDa along the anteroposterior compartment boundary of the wing disc using Scer\GAL4^dpp.blk1 strongly induces disc overgrowth and ectopic wing margin in the dorsal wing pouch. By contrast, Dl^Scer\UAS.cDa expression does not induce ectopic margin ventrally.

(Lai et al., 2005)

Clones of cells expressing Dl^Scer\UAS.cDa in third instar wing discs under the control of Scer\GAL4^Act5C.PI have smooth edges and appear round. Dl^Scer\UAS.cDa expression repositions the compartment boundary away from the normal dorsoventral interface by creating an ectopic stripe of N activation within dorsal cells and eliminating N activation at the dorsoventral interface. Scer\GAL4^Act5C.PI>Dl^Scer\UAS.cDa clones are often associated with an upregulation of F-actin and a smooth interface at the adherens junctions.

(Major and Irvine, 2005)

Overexpression of Dl^Scer\UAS.cDa under control of Scer\GAL4^ey.PH results in overgrown eyes.

(Dominguez et al., 2004)

Expression of Dl^Scer\UAS.cDa under the control of Scer\GAL4^Eq1 results in a slight increase in the number of microchaetae on the adult thorax.

(Ahmed et al., 2003)

Increased numbers of crystal cells are seen in heat shocked Dl^Scer\UAS.cDa; Scer\GAL4^hs.PB larvae at late third instar. These larvae also have increased numbers of prophenoloxidase expressing cells in the larval lymph glands.

(Duvic et al., 2002)

Some hindgut boundary cells form when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^byn-Gal4, but the boundary rows and rings are interrupted.

(Iwaki and Lengyel, 2002)

Expression of Dl^Scer\UAS.cDa, under the control of Scer\GAL4^GMR.PF, results in duplication of eye bristles and melting and smoothing of lens material. There are also extra photoreceptors and extra interommatidial pigment cells. Flies expressing Dl^Scer\UAS.cDa, under the control of either Scer\GAL4^vg.int2.1 or Scer\GAL4^A9, have rudimentary wings.

(Mishra-Gorur et al., 2002)

When Dl^Scer\UAS.cDa is driven by Scer\GAL4^hs.2sev, some ommatidia are seen with abnormal numbers of photoreceptors.

(Strutt et al., 2002)

When Dl^Scer\UAS.cDa is drive by Scer\GAL4^Dll-md23, adult legs show a loss of both growth and segmental joints in the distal leg domains. When Dl^Scer\UAS.cDa is driven by Scer\GAL4^ap-md544, mutant adults have compound tarsal segments. A loss the joint between the T4 and T5 segments is seen, as are misaligned bristles. In the head segment a loss of the basal cylinder of the antenna is also seen.

(Mishra et al., 2001)

Expression of Dl^Scer\UAS.cDa under the control of Scer\GAL4^klu-G410 results in pharate adults at 18^oC. No visible phenotype is seen in the interjoint regions of the femur and tibia, but expansion of the areas which differentiate joint characteristics like naked and thick cuticle is seen in the femoral, tibial and tarsal joints. Tarsal loss is also seen when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^klu-G410 or Scer\GAL4^ap-md544.

(Bishop et al., 1999)

When Dl^Scer\UAS.cDa is expressed in embryos under the control of Scer\GAL4^btl.PS, the number of esg-expressing cells at the tip of the dorsal trunk in the tracheal system is increased.

(Ikeya and Hayashi, 1999)

The normally anterior oocyte nucleus is mislocalised to the posterior of the oocyte when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4¹⁰⁹. An abnormal microtubule organisation, indicative of retention of the posterior microtubule organising centre (MTOC) is seen in oocytes when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^hs.PB, in contrast to wild type where the MTOC disappears from the posterior during mid-oogenesis. No anterior-posterior defects are seen in oocytes expressing Dl^Scer\UAS.cDa under the control of Scer\GAL4^107c1, Scer\GAL4^c709 or Scer\GAL4^A62. Overexpression of Dl^Scer\UAS.cDa under the control of Scer\GAL4^hs.PB results in the formation of long stalklike structures in the germarium. These long stalks do not contain differentiated stalk or polar cells.

(Larkin et al., 1999)

When expression is driven by Scer\GAL4^btl.PS, tracheal phenotypes similar to both loss and gain of function N mutations occur. Ectopic fusions and unfused branches are evident, as well as missing or extra terminal branches, with variable frequency. Cell markers indicate lack or excess of cells expressing fusion and terminal markers.

(Llimargas, 1999)

Formation of normal joints is inhibited in clones in the leg expressing Dl^Scer\UAS.cDa under the control of Scer\GAL4^Act5C.PI, and an ectopic indentation that may represent an incomplete attempt at joint formation is formed. The clones can also result in outgrowth of leg tissue. The outgrowth is composed of a mixture of wild-type cells and cells expressing Dl^Scer\UAS.cDa under the control of Scer\GAL4^Act5C.PI.

(Rauskolb and Irvine, 1999)

When expression is driven by Scer\GAL4^ey.PH, the eye is enlarged, mainly in the dorso-ventral axis. Disruptions in dorsoventral polarity occur.

(Dominguez and de Celis, 1998)

The wing pouch is enlarged in larvae expressing Dl^Scer\UAS.cDa under the control of either Scer\GAL4^dpp.blk1 or Scer\GAL4^ptc-559.1, and cells in the peripheral region of the wing pouch actively divide.

(Go et al., 1998)

Reversals of ommatidial chirality occur equatorially to clones expressing Dl^Scer\UAS.cDa under the control of Scer\GAL4^Act5C.PI.

(Papayannopoulos et al., 1998)

Expression of Dl^Scer\UAS.cDa under the control of Scer\GAL4^dpp.blk1 disrupts joint formation in the tarsal segments, resulting in foreshortened tarsi. An abnormal structure forms at the junction between the first and second tarsal segments, which seems to consist of a partial perpendicular joint.

(de Celis et al., 1998)

Dl^Scer\UAS.cDa causes essentially no phenotype or moderate increases in sense organs and rare hair-to-socket transformations when expressed using Scer\GAL4^sca-537.4 or Scer\GAL4^sca-109-68.

(Doherty et al., 1997)

Ectopic wing margin is formed in dorsal cells of the wing when Dl^Scer\UAS.cDa is expressed using Scer\GAL4^ptc-559.1.

(Panin et al., 1997)

When expression is driven by Scer\GAL4^Ubx.PdC outgrowths of the wing occur only when the clone is induced in the dorsal surface of the wing and in the hinge/pleural region. Thickening of wing veins and notches in the wing margin also occur.

(de Celis and Bray, 1997)

Shifting Dl^Scer\UAS.cDa (insert 30A1) flies carrying Scer\GAL4^ptc-559.1 to 29^oC from 22^oC for 24hr during the second larval instar causes wing outgrowth on the dorsal side of the wing blade. Patches of large bristles similar to anterior double row or posterior wing margin are present at the distal tip of the outgrowth. Other inserts of Dl^Scer\UAS.cDa cause defects in wing, legs, heads, nota and genitalia when driven by Scer\GAL4^ptc-559.1.

(Doherty et al., 1996)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, enhanceable by DEF8^KK101896, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, enhanceable by DEF8^KK101896, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, enhanceable by HINT1^KK108645, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, enhanceable by HINT1^KK108645, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, enhanceable by Mp20^GD11396, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, enhanceable by Mp20^GD11396, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, enhanceable by Tctp^GD11431, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, enhanceable by Tctp^GD11431, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, enhanceable by Liprin-α^KK100116, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, enhanceable by Liprin-α^KK100116, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, enhanceable by Rap1^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, enhanceable by Rap1^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, enhanceable by Cam^KK109037, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, enhanceable by Cam^KK109037, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, enhanceable by Axn^GD1334, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, enhanceable by Axn^GD1334, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Mgat1^KK101668, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by Mgat1^KK101668, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by RhoGAP68F^KK102738, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by RhoGAP68F^KK102738, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by HINT1^KK108645, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by HINT1^KK108645, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Cam^KK109037, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by Cam^KK109037, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Rap1^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by Rap1^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by DEF8^KK101896, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by DEF8^KK101896, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Axn^GD1334, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by Axn^GD1334, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Ide^KK107536, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by Ide^KK107536, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by YL-1^KK100166, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by YL-1^KK100166, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Mp20^GD11396, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by Mp20^GD11396, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Liprin-α^KK100116, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by Liprin-α^KK100116, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Tctp^GD11431, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by Tctp^GD11431, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Hsc70-3^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by Hsc70-3^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Fen1^KK107731, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by Fen1^KK107731, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, enhanceable by Mgat1^KK101668, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, enhanceable by Mgat1^KK101668, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, enhanceable by Ide^KK107536, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, enhanceable by Ide^KK107536, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, enhanceable by YL-1^KK100166, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, enhanceable by YL-1^KK100166, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, enhanceable by RhoGAP68F^KK102738, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, enhanceable by RhoGAP68F^KK102738, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by Not3[+]/Not3^KG10496

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH has increased occurrence of cell division | larval stage phenotype, enhanceable by Not3[+]/Not3^KG10496

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Not3[+]/Not3^KG10496

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by twin^KK108897, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by twin^KK108897, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by Rga^GL00386, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Rga^GL00386, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by Not1^GD9640, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Not1^GD9640, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, enhanceable by Pop2^GD12804, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by Pop2^GD12804, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PU has visible phenotype, enhanceable by Df(3L)iro^EGP7/+

(Barrios et al., 2015)

Delta^UAS.cDa, Scer\GAL4^ey.PU has visible phenotype, enhanceable by caup^KK109669, Scer\GAL4^ey.PU

(Barrios et al., 2015)

Delta^UAS.cDa, Scer\GAL4^ey.PU has visible phenotype, enhanceable by mirr^GD16318, Scer\GAL4^ey.PU

(Barrios et al., 2015)

Delta^UAS.cDa, Scer\GAL4^ey.PU has visible phenotype, enhanceable by ara^KK110191, Scer\GAL4^ey.PU

(Barrios et al., 2015)

Delta^UAS.cDa, Scer\GAL4^ey.PU, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, enhanceable by mirr^DFM3/mirr[+]

(Barrios et al., 2015)

Delta^UAS.cDa, Scer\GAL4^ey.PU, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, enhanceable by mirr^GD16318, Scer\GAL4^ey.PU

(Barrios et al., 2015)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by mir-7^GS(2)518ND2, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by ihog^GD14317, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by ihog^KK112149, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by smo^JF02363, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by ci^GD1403, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by ci^KK100760, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by ci^JF01715, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by hh^JF01804, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, enhanceable by hh^GD193, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PU, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, enhanceable by ct^RNAi.cGa.UAS/BacA\p35^UAS.cUa, Scer\GAL4^ey.PU

(Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PU, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, enhanceable by ct^RNAi.cGa.UAS, Scer\GAL4^ey.PU

(Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PU, ct^RNAi.cGa.UAS has neoplasia phenotype, enhanceable by BacA\p35^UAS.cUa, Scer\GAL4^ey.PU

(Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has abnormal size phenotype, enhanceable by Utx[+]/Utx¹

(Herz et al., 2010)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, enhanceable by ato^RNAi.UAS.J, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, enhanceable by ato^{ERD.UAS.Tag:MYC}, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, enhanceable by bsk^DN.UAS, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible phenotype, enhanceable by Hipk^UAS.Tag:HA, Scer\GAL4^ey.PH

(Lee et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, enhanceable by Rbf¹⁴/Rbf[+]

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible phenotype, enhanceable by Rbf¹⁴/Rbf[+]

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^Eq has visible phenotype, enhanceable by ed^Ext.UAS, Scer\GAL4^Eq

(Ahmed et al., 2003)

Delta^UAS.cDa, Scer\GAL4^sca-537.4 has visible phenotype, enhanceable by bib^UAS.cDa, Scer\GAL4^sca-537.4

(Doherty et al., 1997)

Delta^UAS.cDa, Scer\GAL4^sca-109-68 has visible phenotype, enhanceable by bib^UAS.cDa, Scer\GAL4^sca-109-68

(Doherty et al., 1997)

NOT Enhanced by

Statement

Reference

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, non-enhanceable by Hsc70-3^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, non-enhanceable by Hsc70-3^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, non-enhanceable by Fen1^KK107731, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, non-enhanceable by Fen1^KK107731, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, non-enhanceable by boi^KK103113, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, non-enhanceable by trx^unspecified

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible phenotype, non-enhanceable by trx^unspecified

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, non-enhanceable by ash1^unspecified

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible phenotype, non-enhanceable by ash1^unspecified

(Ferres-Marco et al., 2006)

Suppressed by

Statement

Reference

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, suppressible by Hsc70-5^KK100233, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, suppressible by Ip259^KK101346, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, suppressible by Arf1^KK101396, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, suppressible by Hsc70-5^KK100233, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, suppressible by Arf1^KK101396, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, suppressible by Ip259^KK101346, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, suppressible by Ip259^KK101346, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, suppressible by Ip259^KK101346, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has visible | adult stage phenotype, suppressible by Hsc70-5^KK100233, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, suppressible by Hsc70-5^KK100233, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has visible | adult stage phenotype, suppressible by upd3^Δ

(Vicente et al., 2018)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, suppressible by upd3^Δ

(Vicente et al., 2018)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has visible | adult stage phenotype, suppressible by Fancl^GD7835, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has visible | adult stage phenotype, suppressible by CycB^HMS01015, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has visible | adult stage phenotype, suppressible by CycB²

(Vicente et al., 2018)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, suppressible by CycB^HMS01015, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, suppressible by Fancl^GD7835, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype, suppressible by CycB²

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has visible | adult stage phenotype, suppressible | partially by upd3^Δ

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has neoplasia | adult stage phenotype, suppressible | partially by upd3^Δ

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has visible | adult stage phenotype, suppressible | partially by upd3^Δ/upd2^Δ

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has visible | adult stage phenotype, suppressible | partially by CycB^HMS01015, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has visible | adult stage phenotype, suppressible | partially by Fancl^GD7835, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has visible | adult stage phenotype, suppressible | partially by Df(1)os^o

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has visible | adult stage phenotype, suppressible | partially by CycB²

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has neoplasia | adult stage phenotype, suppressible | partially by Df(1)os^o

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has neoplasia | adult stage phenotype, suppressible | partially by Fancl^GD7835, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has neoplasia | adult stage phenotype, suppressible | partially by upd3^Δ/upd2^Δ

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has neoplasia | adult stage phenotype, suppressible | partially by CycB²

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has neoplasia | adult stage phenotype, suppressible | partially by CycB^HMS01015, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, suppressible by Not3^UAS.cVa, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has increased occurrence of cell division | larval stage phenotype, suppressible by Not3^UAS.cVa, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, suppressible by Not3^UAS.cVa, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, suppressible by Not3^ΔCC.UAS, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, suppressible by Not3^ΔCC.UAS, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, mir-7^UAS.cLb has visible | adult stage phenotype, suppressible by boi^UAS.cHa, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH, mir-7^UAS.cLb has visible | adult stage phenotype, suppressible by hh^UAS.cCa, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH, mir-7^UAS.cLb has visible | adult stage phenotype, suppressible | partially by ci^UAS.Tag:HA, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has abnormal developmental rate phenotype, suppressible by Ilp8^MI00727

(Garelli et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PU, ct^RNAi.cGa.UAS has neoplasia phenotype, suppressible | partially by Pi3K92E^KK102291, Scer\GAL4^ey.PU

(Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, suppressible by mir-8^SC1, Scer\GAL4^ey.PH

(Vallejo et al., 2011)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, suppressible by ato^UAS.cJa, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, suppressible by dap^UAS.cUa, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, suppressible by Jra^UAS.cEa, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, suppressible by Mmus\Atoh1^UAS.cQa, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, suppressible by HDAC1⁰⁴⁵⁵⁶/Rpd3[+]

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, suppressible by Su(var)3-9[+]/Su(var)3-9¹⁷

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, suppressible by E(z)[+]/E(z)⁷³¹

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible phenotype, suppressible by HDAC1⁰⁴⁵⁵⁶/Rpd3[+]

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible phenotype, suppressible by Su(var)3-9[+]/Su(var)3-9¹⁷

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible phenotype, suppressible by E(z)[+]/E(z)⁷³¹

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype, suppressible by Rbf^UAS.cDa, Scer\GAL4^ey.PH

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible phenotype, suppressible by Rbf^UAS.cDa, Scer\GAL4^ey.PH

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ptc-559.1 has lethal phenotype, suppressible by N^l1N-ts1

(Doherty et al., 1996)

NOT suppressed by

Statement

Reference

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, non-suppressible by Hsc70-3^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, non-suppressible by Fen1^KK107731, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, non-suppressible by Hsc70-3^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, non-suppressible by Fen1^KK107731, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has increased cell death | larval stage phenotype, non-suppressible by Not3^UAS.cVa, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype, non-suppressible by Not3^ΔNB.UAS, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype, non-suppressible by Not3^ΔNB.UAS, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Enhancer of

Statement

Reference

Delta^UAS.cDa, Scer\GAL4^Eq is an enhancer of visible phenotype of Scer\GAL4^Eq, ed^Ext.UAS

(Ahmed et al., 2003)

Delta^UAS.cDa, Scer\GAL4^sca-109-68 is an enhancer of visible phenotype of Scer\GAL4^sca-109-68, bib^UAS.cDa

(Doherty et al., 1997)

Delta^UAS.cDa, Scer\GAL4^sca-537.4 is an enhancer of visible phenotype of Scer\GAL4^sca-537.4, bib^UAS.cDa

(Doherty et al., 1997)

Suppressor of

Statement

Reference

Delta^UAS.cDa, Scer\GAL4^bbg-C96 is a suppressor of visible phenotype of Nsf2^EQ.UAS, Scer\GAL4^bbg-C96

(Stewart et al., 2001)

Scer\GAL4^32B/Delta^UAS.cDa is a suppressor of visible phenotype of nmo^unspecified

(Verheyen et al., 2001)

Other

Statement

Reference

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible | adult stage phenotype

(Even et al., 2019, Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia | adult stage phenotype

(Even et al., 2019, Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has visible | adult stage phenotype

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has neoplasia | adult stage phenotype

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has increased cell death | larval stage phenotype

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has abnormal size | adult stage phenotype

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has increased occurrence of cell division | larval stage phenotype

(Vicente et al., 2018)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has visible | adult stage phenotype

(Vicente et al., 2018)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has neoplasia | adult stage phenotype

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PU, lola^GS88A8, psq^GS88A8 has neoplasia phenotype

(Barrios et al., 2015, Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PH, mir-7^UAS.cLb has visible | adult stage phenotype

(Da Ros et al., 2013)

Delta^UAS.cDa, Not3^GD4068, Scer\GAL4^ey.PH has neoplasia phenotype

(De Keersmaecker et al., 2013)

Delta^UAS.cDa, Not3^KG10496, Scer\GAL4^ey.PH has neoplasia phenotype

(De Keersmaecker et al., 2013)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has neoplasia phenotype

(De Keersmaecker et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has abnormal developmental rate phenotype

(Garelli et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PU, ct^RNAi.cGa.UAS has neoplasia phenotype

(Zhai et al., 2012)

Delta^UAS.cDa, Pi3K92E^KK102291, Scer\GAL4^ey.PU has visible phenotype

(Zhai et al., 2012)

Delta^UAS.cDa, ItgaPS4^KK105806, Scer\GAL4^ey.PU has neoplasia phenotype

(Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PU, mys^HMS00043 has neoplasia phenotype

(Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PU, Timp^KK108268 has neoplasia phenotype

(Zhai et al., 2012)

BacA\p35^UAS.cUa, Delta^UAS.cDa, Scer\GAL4^ey.PU, vvl^JF02126 has neoplasia phenotype

(Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has neoplasia phenotype

(Vallejo et al., 2011, Bossuyt et al., 2009, Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, mir-8^SC1, psq^GS88A8 has lethal | adult stage phenotype

(Vallejo et al., 2011)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has abnormal size phenotype

(Herz et al., 2010)

Delta^UAS.cDa, Scer\GAL4^ey.PH, ato^{ERD.UAS.Tag:MYC} has neoplasia phenotype

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, ato^RNAi.UAS.J has neoplasia phenotype

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, ato^UAS.cJa, lola^GS88A8, psq^GS88A8 has increased cell death | third instar larval stage phenotype

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, bsk^DN.UAS has neoplasia phenotype

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, ato^UAS.cJa, bsk^DN.UAS, lola^GS88A8, psq^GS88A8 has neoplasia phenotype

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^Bx-MS1096, lola^GS88A8, psq^GS88A8 has neoplasia phenotype

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^dpp.blk1, lola^GS88A8, psq^GS88A8 has neoplasia phenotype

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has visible phenotype

(Ferres-Marco et al., 2006)

Phenotype Manifest In

Enhanced by

Statement

Reference

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by HINT1^KK108645, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by Mp20^GD11396, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by Tctp^GD11431, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by Liprin-α^KK100116, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by Rap1^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by Cam^KK109037, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by Axn^GD1334, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Mgat1^KK101668, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by RhoGAP68F^KK102738, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by HINT1^KK108645, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Cam^KK109037, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Rap1^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by DEF8^KK101896, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Axn^GD1334, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Ide^KK107536, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by YL-1^KK100166, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Mp20^GD11396, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Liprin-α^KK100116, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Tctp^GD11431, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Hsc70-3^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Fen1^KK107731, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by Mgat1^KK101668, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by Ide^KK107536, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by YL-1^KK100166, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by RhoGAP68F^KK102738, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by DEF8^KK101896, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Not3[+]/Not3^KG10496

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye disc phenotype, enhanceable by Not3[+]/Not3^KG10496

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by twin^KK108897, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Rga^GL00386, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Not1^GD9640, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Pop2^GD12804, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PU has wing phenotype, enhanceable by Df(3L)iro^EGP7/+

(Barrios et al., 2015)

Delta^UAS.cDa, Scer\GAL4^ey.PU has eye phenotype, enhanceable by caup^KK109669, Scer\GAL4^ey.PU

(Barrios et al., 2015)

Delta^UAS.cDa, Scer\GAL4^ey.PU has wing phenotype, enhanceable by mirr^GD16318, Scer\GAL4^ey.PU

(Barrios et al., 2015)

Delta^UAS.cDa, Scer\GAL4^ey.PU has wing phenotype, enhanceable by ara^KK110191, Scer\GAL4^ey.PU

(Barrios et al., 2015)

Delta^UAS.cDa, Scer\GAL4^ey.PU, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by mirr^DFM3/mirr[+]

(Barrios et al., 2015)

Delta^UAS.cDa, Scer\GAL4^ey.PU, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by mirr^GD16318, Scer\GAL4^ey.PU

(Barrios et al., 2015)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by mir-7^GS(2)518ND2, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by ihog^GD14317, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by ihog^KK112149, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by boi^KK103113, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by smo^JF02363, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by ci^GD1403, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by ci^KK100760, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by ci^JF01715, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by hh^JF01804, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by hh^GD193, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Not3^KG10496

(De Keersmaecker et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PU, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by ct^RNAi.cGa.UAS/BacA\p35^UAS.cUa, Scer\GAL4^ey.PU

(Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PU, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by ct^RNAi.cGa.UAS, Scer\GAL4^ey.PU

(Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PU, ct^RNAi.cGa.UAS has eye phenotype, enhanceable by BacA\p35^UAS.cUa, Scer\GAL4^ey.PU

(Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by Utx[+]/Utx¹

(Herz et al., 2010)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by ato^RNAi.UAS.J, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by ato^{ERD.UAS.Tag:MYC}, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye disc | third instar larval stage phenotype, enhanceable by ato^{ERD.UAS.Tag:MYC}, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye disc | third instar larval stage phenotype, enhanceable by ato^{ERD.UAS.Tag:MYC}, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by bsk^DN.UAS, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, enhanceable by Hipk^UAS.Tag:HA, Scer\GAL4^ey.PH

(Lee et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, enhanceable by Rbf¹⁴/Rbf[+]

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^Eq has microchaeta | ectopic phenotype, enhanceable by ed^Ext.UAS, Scer\GAL4^Eq

(Ahmed et al., 2003)

Delta^UAS.cDa, Scer\GAL4^sca-537.4 has sense organ phenotype, enhanceable by bib^UAS.cDa, Scer\GAL4^sca-537.4

(Doherty et al., 1997)

Delta^UAS.cDa, Scer\GAL4^sca-109-68 has sense organ phenotype, enhanceable by bib^UAS.cDa, Scer\GAL4^sca-109-68

(Doherty et al., 1997)

NOT Enhanced by

Statement

Reference

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, non-enhanceable by Hsc70-3^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, non-enhanceable by Fen1^KK107731, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, non-enhanceable by trx^unspecified

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, non-enhanceable by ash1^unspecified

(Ferres-Marco et al., 2006)

Suppressed by

Statement

Reference

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, suppressible by Hsc70-5^KK100233, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, suppressible by Ip259^KK101346, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, suppressible by Arf1^KK101396, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, suppressible by Hsc70-5^KK100233, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH has eye phenotype, suppressible by Ip259^KK101346, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has eye phenotype, suppressible by Fancl^GD7835, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has eye phenotype, suppressible by CycB^HMS01015, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has eye phenotype, suppressible by CycB²

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has eye phenotype, suppressible | partially by upd3^Δ

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has eye phenotype, suppressible | partially by CycB²

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has eye phenotype, suppressible | partially by upd3^Δ/upd2^Δ

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has eye phenotype, suppressible | partially by Fancl^GD7835, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has eye phenotype, suppressible | partially by Df(1)os^o

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has eye phenotype, suppressible | partially by CycB^HMS01015, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, suppressible by Not3^UAS.cVa, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye disc phenotype, suppressible by Not3^UAS.cVa, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, suppressible by Not3^ΔCC.UAS, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has eye phenotype, suppressible by upd3^Δ

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PH, mir-7^UAS.cLb has eye phenotype, suppressible by boi^UAS.cHa, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH, mir-7^UAS.cLb has eye phenotype, suppressible by hh^UAS.cCa, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH, mir-7^UAS.cLb has eye phenotype, suppressible | partially by ci^UAS.Tag:HA, Scer\GAL4^ey.PH

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PU, ct^RNAi.cGa.UAS has eye phenotype, suppressible | partially by Pi3K92E^KK102291, Scer\GAL4^ey.PU

(Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, suppressible by mir-8^SC1, Scer\GAL4^ey.PH

(Vallejo et al., 2011)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye-antennal disc phenotype, suppressible by mir-8^SC1, Scer\GAL4^ey.PH

(Vallejo et al., 2011)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, suppressible by ato^UAS.cJa, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye disc | third instar larval stage phenotype, suppressible by ato^UAS.cJa, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, suppressible by dap^UAS.cUa, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, suppressible by Jra^UAS.cEa, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, suppressible by Mmus\Atoh1^UAS.cQa, Scer\GAL4^ey.PH

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, suppressible by HDAC1⁰⁴⁵⁵⁶/Rpd3[+]

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, suppressible by Su(var)3-9[+]/Su(var)3-9¹⁷

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, suppressible by E(z)[+]/E(z)⁷³¹

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, suppressible by Rbf^UAS.cDa, Scer\GAL4^ey.PH

(Ferres-Marco et al., 2006)

Delta^UAS.cDa has wing disc | dorsal phenotype, suppressible by Scer\GAL4^dpp.blk1

(Lai et al., 2005)

Delta^UAS.cDa, Scer\GAL4^ap-md544 has basal cylinder phenotype, suppressible | partially by N^l1N-ts1

(Mishra et al., 2001)

Delta^UAS.cDa, Scer\GAL4^ap-md544 has leg joint phenotype, suppressible by N^l1N-ts1

(Mishra et al., 2001)

Delta^UAS.cDa, Scer\GAL4^ap-md544 has leg | distal phenotype, suppressible by N^l1N-ts1

(Mishra et al., 2001)

Delta^UAS.cDa, Scer\GAL4^ap-md544 has tarsal segment 4 phenotype, suppressible by N^l1N-ts1

(Mishra et al., 2001)

Delta^UAS.cDa, Scer\GAL4^ap-md544 has pretarsus phenotype, suppressible by N^l1N-ts1

(Mishra et al., 2001)

NOT suppressed by

Statement

Reference

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, non-suppressible by Hsc70-3^RNAi.UAS.cUa, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype, non-suppressible by Fen1^KK107731, Scer\GAL4^ey.PH

(Even et al., 2019)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye disc phenotype, non-suppressible by Not3^ΔNB.UAS, Scer\GAL4^ey.PH

(Vicente et al., 2018)

Enhancer of

Statement

Reference

Delta^UAS.cDa, Scer\GAL4^Eq is an enhancer of microchaeta | ectopic phenotype of Scer\GAL4^Eq, ed^Ext.UAS

(Ahmed et al., 2003)

Delta^UAS.cDa, Scer\GAL4^sca-109-68 is an enhancer of sense organ phenotype of Scer\GAL4^sca-109-68, bib^UAS.cDa

(Doherty et al., 1997)

Delta^UAS.cDa, Scer\GAL4^sca-537.4 is an enhancer of sense organ phenotype of Scer\GAL4^sca-537.4, bib^UAS.cDa

(Doherty et al., 1997)

Suppressor of

Statement

Reference

Delta^UAS.cDa/Scer\GAL4^elav.PLu is a suppressor of cone cell phenotype of sno⁹³ⁱ/sno^71e1

(Tsuda et al., 2002)

Delta^UAS.cDa/Scer\GAL4^elav.PLu is a suppressor of cone cell phenotype of ebi^E4/ebi^P7

(Tsuda et al., 2002)

Delta^UAS.cDa, Scer\GAL4^bbg-C96 is a suppressor of wing margin phenotype of Nsf2^EQ.UAS, Scer\GAL4^bbg-C96

(Stewart et al., 2001)

Scer\GAL4^32B/Delta^UAS.cDa is a suppressor of wing vein | ectopic phenotype of nmo^unspecified

(Verheyen et al., 2001)

NOT Suppressor of

Statement

Reference

Delta^UAS.cDa, Scer\GAL4^dpp.blk1 is a non-suppressor of wing disc phenotype of Scer\GAL4^dpp.blk1, mib1^{ΔRF.UAS.Tag:polyHis,Tag:MYC}

(Lai et al., 2005)

Scer\GAL4^btl.PS/Delta^UAS.cDa is a non-suppressor of embryonic/larval tracheal dorsal trunk phenotype of arm⁴

(Chihara and Hayashi, 2000)

Other

Statement

Reference

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye phenotype

(Even et al., 2019, Vicente et al., 2018, Vallejo et al., 2011, Herz et al., 2010, Bossuyt et al., 2009, Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye disc phenotype

(Vicente et al., 2018, Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^ey.PH, twin^KK108897 has eye phenotype

(Vicente et al., 2018)

Delta^UAS.cDa, Not3^KK102144, Scer\GAL4^ey.PH has eye phenotype

(Vicente et al., 2018)

Delta^UAS.cDa, Scer\GAL4^ey.PU, lola^GS88A8, psq^GS88A8 has eye phenotype

(Barrios et al., 2015, Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PH, ct^RNAi.cGa.UAS has eye phenotype

(Wong et al., 2014)

Delta^UAS.cDa, Scer\GAL4^ey.PH, mir-7^UAS.cLb has eye phenotype

(Da Ros et al., 2013)

Delta^UAS.cDa, Scer\GAL4^ey.PH, mir-7^UAS.cLb has eye disc | third instar larval stage phenotype

(Da Ros et al., 2013)

Delta^UAS.cDa, Pi3K92E^KK102291, Scer\GAL4^ey.PU has eye phenotype

(Zhai et al., 2012)

Delta^UAS.cDa, ItgaPS4^KK105806, Scer\GAL4^ey.PU has eye phenotype

(Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PU, mys^HMS00043 has eye phenotype

(Zhai et al., 2012)

BacA\p35^UAS.cUa, Delta^UAS.cDa, Scer\GAL4^ey.PU, vvl^JF02126 has eye phenotype

(Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PU, ct^RNAi.cGa.UAS has eye phenotype

(Zhai et al., 2012)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye-antennal disc phenotype

(Vallejo et al., 2011)

Delta^UAS.cDa, Scer\GAL4^ey.PH, ato^{ERD.UAS.Tag:MYC} has eye phenotype

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, ato^{ERD.UAS.Tag:MYC} has eye disc | third instar larval stage phenotype

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, ato^RNAi.UAS.J has eye phenotype

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, ato^UAS.cJa, lola^GS88A8, psq^GS88A8 has eye disc | third instar larval stage phenotype

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, bsk^DN.UAS has eye phenotype

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, ato^UAS.cJa, bsk^DN.UAS, lola^GS88A8, psq^GS88A8 has eye phenotype

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8 has eye disc | third instar larval stage phenotype

(Bossuyt et al., 2009)

Delta^UAS.cDa, Scer\GAL4^sca-537.4, neur^{UAS.PA.Tag:V5} has salivary gland phenotype

(Commisso and Boulianne, 2008)

Delta^UAS.cDa, Scer\GAL4^Bx-MS1096, lola^GS88A8, psq^GS88A8 has wing disc phenotype

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^dpp.blk1, lola^GS88A8, psq^GS88A8 has wing disc phenotype

(Ferres-Marco et al., 2006)

Delta^UAS.cDa, Scer\GAL4^dpp.blk1, mib1^{UAS.Tag:polyHis,Tag:MYC} has wing disc | ventral phenotype

(Lai et al., 2005)

Delta^UAS.cDa, Scer\GAL4^ey.PH, eyg^XE119/eyg^PxA1 has eye phenotype

(Dominguez et al., 2004)

Delta^UAS.cDa, Scer\GAL4^ptc-559.1, fng^D4 has wing phenotype

(Panin et al., 1997)

Delta^UAS.cDa, Scer\GAL4^ptc-559.1, fng^UAS.cKa has wing phenotype

(Panin et al., 1997)

Delta^UAS.cDa, Scer\GAL4^ptc-559.1, fng^UAS.cKa has wing | ventral phenotype

(Panin et al., 1997)

Delta^UAS.cDa, Scer\GAL4^ptc-559.1, fng^D4 has wing | ventral phenotype

(Panin et al., 1997)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of lola^GS88A8. psq^GS88A8 and Dl^UAS.cDa under the control of Scer\GAL4^ey.PH leads to eye tumor and metastasis.

(Even et al., 2019)

The triple expression of Dl^UAS.cDa, lola^GS88A8 and psq^GS88A8 under the control of Scer\GAL4^ey.PH induces excessively enlarged eyes and eye tumors and macroscopically visible metastases, as compared to controls. The eye disc shows a disorganized epithelium with defects in the pattern of differentiated cell; there is a decrease in cell divisions (BrdU labelling and pH3 immunostaining) and an increase in apoptosis (Dcp1a immunostaining), as compared to controls.

(Vicente et al., 2018)

Expression of caup^KK109669 enhances both the size and number of eyes that exhibit severe folding when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PU.

Expression of mirr^GD16318 enhances both the size and number of eyes that exhibit severe folding when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PU.

Expression of ara^KK110191 enhances both the size and number of eyes that exhibit severe folding when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PU.

One copy of Df(3L)iro^EGP7 enhances both the size and number of eyes that exhibit severe folding when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PU.

Co-expression of Dl^Scer\UAS.cDa with lola and psq (using P{GSV1}lola^GS88A8, which is comprised of the lola^GS88A8 and psq^GS88A8 alleles) under the control of Scer\GAL4^ey.PU induces tumor-like overgrowths in the eye.

The tumor-like overgrowth phenotype seen when Dl^Scer\UAS.cDa is co-expressed P{GSV1}lola^GS88A8 (comprised of the lola^GS88A8 and psq^GS88A8) under the control of Scer\GAL4^ey.PU is seen with increased frequency when one copy of mirr^DFM3 is also present.

(Barrios et al., 2015)

Co-expression of Dl^Scer\UAS.cDa with ct^{dsRNA.cGa.Scer\UAS}, under the control of Scer\GAL4^ey.PH results in dramatically altered eyes.

(Wong et al., 2014)

mir-7^GS(2)518ND2 enhances the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PH. Eyes are 250%-320% larger than wild type eyes and the phenotype is seen with 54% penetrance.

Co-expression of mir-7^Scer\UAS.cLb and Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PH results in overgrown eye discs, resulting in overgrown and folded eyes in 70% of flies.

ihog^GD14317 enhances the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PH. 80% of flies have severely overgrown eyes.

ihog^KK112149 enhances the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PH. 80% of flies have severely overgrown eyes.

boi^KK103113 is unable to enhance the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PH.

Expression of boi^Scer\UAS.cHa fully suppresses the eye disc overgrowth seen when mir-7^Scer\UAS.cLb and Dl^Scer\UAS.cDa are co-expressed under the control of Scer\GAL4^ey.PH.

smo^GD577 enhances the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PH. Approximately 80% of flies exhibit eye overgrowth.

smo^JF02363 enhances the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PH. Approximately 80% of flies exhibit eye overgrowth.

ci^GD1403 enhances the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PH, resulting in flies with secondary eye growths within the thorax and abdomen. The phenotype is seen with 100% penetrance.

ci^KK100760 enhances the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PH, resulting in flies with secondary eye growths within the thorax and abdomen. The phenotype is seen with 10% penetrance.

ci^JF01715 enhances the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PH, resulting in flies with secondary eye growths within the thorax and abdomen. The phenotype is seen with 100% penetrance.

hh^JF01804 enhances the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PH. The phenotype is seen with 100% penetrance.

hh^GD193 enhances the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PH. 30% of flies exhibit eye overgrowth.

Expression of hh^Scer\UAS.cCa suppresses the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa and mir-7^Scer\UAS.cLb are expressed under the control of Scer\GAL4^ey.PH. The phenotype is seen with 100% penetrance.

Expression of ci^{Scer\UAS.T:Ivir\HA1} partially suppresses the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa and mir-7^Scer\UAS.cLb are expressed under the control of Scer\GAL4^ey.PH. Many eyes are substantially reduced in size but still exhibit abnormal patterned growth.

ci^76.Scer\UAS enhances the eye overgrowth phenotype seen when Dl^Scer\UAS.cDa is expressed under the control of Scer\GAL4^ey.PH. Eye overgrowth is seen with 75% penetrance.

Eye discs from flies expressing Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PH and also carrying small patches of hh^AC cells are 170% larger than control wild type eye discs, and 126% larger than flies expressing Dl^Scer\UAS.cDa alone.

(Da Ros et al., 2013)

Addition of Not3^GD4068, Not3^KK102144 or Not3^KG10496 to the Scer\GAL4^ey.PH Dl^Scer\UAS.cDa background markedly increases tumor incidence in the eyes.

(De Keersmaecker et al., 2013)

Co-expression of Dl^Scer\UAS.cDa, lola^GS88A8 and psq^GS88A8 using Scer\GAL4^ey.PH (the so-called 'eyeful' background) results in a delay in pupariation of 26.6 +/- 7.5 hours. This is reverted to a delay of 5.9 +/- 7.1 hours in a Ilp8^MI00727 background.

(Garelli et al., 2012)

72.5% of flies expressing Dl^Scer\UAS.cDa, psq^GS88A8 and lola^GS88A8 under the control of Scer\GAL4^ey.PU have eye tumours, with 4.9% having macroscopically visible secondary tumour growths derived from the developing retina. The incidence of primary and secondary tumours in these "eyeful" flies is slightly enhanced by co-expression of ct^{dsRNA.cGa.Scer\UAS}, but is greatly enhanced if the "eyeful" flies also co-express both ct^{dsRNA.cGa.Scer\UAS} and BacA\p35^Scer\UAS.cUa.

Flies co-expressing ct^{dsRNA.cGa.Scer\UAS} and Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PU show a low frequency of primary eye tumours and secondary tumours. The incidence of primary and secondary tumours is enhanced by co-expression of BacA\p35^Scer\UAS.cUa.

Co-expression of Pi3K92E^KK102291 partially suppresses the tumorous eye growth seen in flies co-expressing ct^{dsRNA.cGa.Scer\UAS} and Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PU.

Flies co-expressing Pi3K92E^KK102291 and Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PU have small eyes.

Flies co-expressing Timp^KK108268 and Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PU show a low frequency of secondary tumours.

Flies co-expressing mys^HMS00043 and Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PU show a high frequency of primary eye tumours and a low frequency of secondary tumours.

Flies co-expressing αPS4^KK105806 and Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PU show a high frequency of primary eye tumours and a low frequency of secondary tumours.

Flies co-expressing vvl^JF02126, Dl^Scer\UAS.cDa and BacA\p35^Scer\UAS.cUa under the control BacA\p35^Scer\UAS.cUaof Scer\GAL4^ey.PU show a low frequency of primary eye tumours and of secondary tumours.

(Zhai et al., 2012)

Flies expressing Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PH and also carrying the P{GSV1}lola^GS88A8 insertion (which causes overexpression of psq and lola) show an eye tumour phenotype. In addition, distant metastasis in the thorax and abdomen is seen in 15% of cases. Co-expression of mir-8^SC1 significantly reduces the primary eye tumour size, completely inhibits the incidence of metastases and results in a high incidence of adult lethality.

(Vallejo et al., 2011)

Scer\GAL4^ey.PH-mediated expression of Dl^Scer\UAS.cDa, psq^GS88A8 and lola^GS88A8 causes mild overgrowth of the eye (the 'eyeful' phenotype) at 18[o]C. This phenotype is enhanced by heterozygosity for Utx¹ : approximately 80% of flies show enlarged ventral halves of the eyes, while the remaining 20% have ventrally located outgrowths and ectopic eye tissue.

(Herz et al., 2010)

Scer\GAL4^ey.PH-mediated co-expression of Dl^Scer\UAS.cDa, psq^GS88A8 and lola^GS88A8 ("eyeful" flies) results in excessively enlarged eyes, and eye tumours occur in 57% of eyes, with 3% of flies showing macroscopically visible metastases derived from the developing retina.

Co-expression of ato^Scer\UAS.cJa almost completely suppresses the formation of eye tumours seen in 'eyeful' (Scer\GAL4^ey.PH, Dl^Scer\UAS.cDa, psq^GS88A8, lola^GS88A8) flies.

Co-expression of ato^{dsRNA.Scer\UAS.J} results in a dramatic increase in tumour and metastases incidence in 'eyeful' (Scer\GAL4^ey.PH, Dl^Scer\UAS.cDa, psq^GS88A8, lola^GS88A8) flies.

Co-expression of ato^{Scer\UAS.T:Rep-en.T:Hsap\MYC} results in a dramatic increase in tumour and metastases incidence in 'eyeful' (Scer\GAL4^ey.PH, Dl^Scer\UAS.cDa, psq^GS88A8, lola^GS88A8) flies: differentiated eye tissue is lost in 30% of the eye fields, and tumors are seen in 100% of the remaining eyes. These tumors include large patches of undifferentiated tissue.

Co-expression of ato^{Scer\UAS.T:Rep-en.T:Hsap\MYC} in a Scer\GAL4^ey.PH Dl^Scer\UAS.cDa background leads to loss of retinal differentiation and to a 9% de novo tumor incidence in the remaining eye fields, with 6% of flies showing metastasis.

Co-expression of ato^{dsRNA.Scer\UAS.J} in a Scer\GAL4^ey.PH Dl^Scer\UAS.cDa background leads to tumors in 0.5% of eyes, with 0.3% of flies showing metastasis (mostly present in the thorax and head).

Co-expression of ato^Scer\UAS.cJa in 'eyeful' third instar eye discs (Scer\GAL4^ey.PH, Dl^Scer\UAS.cDa, psq^GS88A8, lola^GS88A8) results in dramatically increased apoptosis, as measured by decay staining.

Scer\GAL4^ey.PH-mediated co-expression of Dl^Scer\UAS.cDa, psq^GS88A8 and lola^GS88A8 ("eyeful") third instar eye discs exhibit increased cell proliferation (as measured by phospho-histoneH3) posterior to the second mitotic wave.

Co-expression of ato^Scer\UAS.cJa reduces ectopic proliferation in "eyeful" (Scer\GAL4^ey.PH Dl^Scer\UAS.cDa, psq^GS88A8 and lola^GS88A8) third instar eye discs.

Co-expression of ato^{Scer\UAS.T:Rep-en.T:Hsap\MYC} increases ectopic proliferation in "eyeful" (Scer\GAL4^ey.PH Dl^Scer\UAS.cDa, psq^GS88A8 and lola^GS88A8) third instar eye discs.

Co-expression of ato^{Scer\UAS.T:Rep-en.T:Hsap\MYC} in a Scer\GAL4^ey.PH Dl^Scer\UAS.cDa background leads to the appearance of significant numbers of proliferating cells in the posterior region of third instar eye discs.

Co-expression of ato^{Scer\UAS.T:Rep-en.T:Hsap\MYC} in Scer\GAL4^ey.PH Dl^Scer\UAS.cDa third instar eye discs increases the proportion of undifferentiated to differentiated cells and, in some cases, results in lobes of proliferative and undifferentiated tissue.

"Eyeful" (Scer\GAL4^ey.PH Dl^Scer\UAS.cDa, psq^GS88A8 and lola^GS88A8) third instar eye discs exhibit disorganization of the epithelium.

Co-expression of ato^Scer\UAS.cJa restores the size and organization of "eyeful" (Scer\GAL4^ey.PH Dl^Scer\UAS.cDa, psq^GS88A8 and lola^GS88A8) third instar eye discs.

Co-expression of ato^{Scer\UAS.T:Rep-en.T:Hsap\MYC} severely worsens the retinal patterning of "eyeful" (Scer\GAL4^ey.PH Dl^Scer\UAS.cDa, psq^GS88A8 and lola^GS88A8) third instar eye discs, to the extent that the morphogenetic furrow is difficult to discriminate.

Co-expression of dap^Scer\UAS.cUa leads to a significant inhibition of the tumor occurrence and a partial reduction in the metastasis seen in 'eyeful' (Scer\GAL4^ey.PH, Dl^Scer\UAS.cDa, psq^GS88A8, lola^GS88A8) flies.

Co-expression of bsk^DN.Scer\UAS in the 'eyeful' (Scer\GAL4^ey.PH, Dl^Scer\UAS.cDa, psq^GS88A8, lola^GS88A8) background leads to tumors in 61% of eyes and an approximately 7-fold increase in metastasis.

Co-expression of bsk^DN.Scer\UAS in a Scer\GAL4^ey.PH Dl^Scer\UAS.cDa background leads to the induction of tumors and metastasis.

Co-expression of Jra^Scer\UAS.cEa reduces tumor and metastasis incidence in the 'eyeful' (Scer\GAL4^ey.PH, Dl^Scer\UAS.cDa, psq^GS88A8, lola^GS88A8) background.

Co-expression of bsk^DN.Scer\UAS in a ato^Scer\UAS.cJa 'eyeful' (Scer\GAL4^ey.PH, Dl^Scer\UAS.cDa, psq^GS88A8, lola^GS88A8) background leads to a suppression of the inhibitory effects of ato^Scer\UAS.cJa on the 'eyeful' tumor phenotype, restoring tumor formation and enhancing metastasis.

(Bossuyt et al., 2009)

The eye overproliferation defect caused by expression of Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PH is enhanced by co-expression of hipk^{Scer\UAS.T:Ivir\HA1}.

(Lee et al., 2009)

Co-expression of Dl^Scer\UAS.cDa and neur^{Scer\UAS.PA.T:SV5\V5} under the control of Scer\GAL4^sca-537.4 results in mild defects in salivary gland morphology.

(Commisso and Boulianne, 2008)

Flies expressing Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PH and also carrying the P{GSV1}lola^GS88A8 insertion (which results

in the lola^GS88A8 and psq^GS88A8 alleles being expressed under

the control of Scer\GAL4^ey.PH) usually develop tumours in the eyes.

Additionally, in approximately 30% of the flies, secondary eye growths

are seen throughout the body, with the whole body filling up with eye

tissue in some cases. The secondary eye growths have ragged borders,

indicating invasion of the mutant tissue into the surrounding normal

tissue.

Eye discs show massive uncontrolled overgrowth in animals expressing

Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PH and also

carrying the P{GSV1}lola^GS88A8 insertion (which results in the

lola^GS88A8 and psq^GS88A8 alleles being expressed under the

control of Scer\GAL4^ey.PH). In most of the discs, the epithelial

cells have lost their apical-basal polarity and some have a disrupted

basement membrane and grow without differentiating.

Wing discs of animals expressing Dl^Scer\UAS.cDa under the control

of Scer\GAL4^dpp.blk1 and also carrying the P{GSV1}lola^GS88A8

insertion (which results in the lola^GS88A8 and psq^GS88A8 alleles

being expressed under the control of Scer\GAL4^dpp.blk1) show massive

overgrowth and mutant cells are found invading adjacent regions of

the disc.

Wing discs of animals expressing Dl^Scer\UAS.cDa under the control

of Scer\GAL4^Bx-MS1096 and also carrying the P{GSV1}lola^GS88A8

insertion (which results in the lola^GS88A8 and psq^GS88A8 alleles

being expressed under the control of Scer\GAL4^Bx-MS1096) show massive

overgrowth, which initiates in the dorsal region but progressively

extends to occupy the whole disc.

Flies expressing Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PH

and also carrying psq^GS88A8 and lola^rev6 have reduced eye tumour

size (compared to flies expressing Dl^Scer\UAS.cDa under the control

of Scer\GAL4^ey.PH and also carrying psq^GS88A8 and lola^GS88A8)

but show sporadic secondary growth of eye tissue.

Flies expressing Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PH

and also carrying lola^GS88A8 and one of the following psq alleles

do not produce eye tumours or metastases; psq^rev7, psq^rev9,

psq^rev2, psq^rev4, psq^rev14, psq^rev12.

The eye tumour phenotype of flies expressing Dl^Scer\UAS.cDa under

the control of Scer\GAL4^ey.PH and also carrying the P{GSV1}lola^GS88A8

insertion (which results in the lola^GS88A8 and psq^GS88A8 alleles

being expressed under the control of Scer\GAL4^ey.PH) is dominantly

suppressed by one of Rpd3⁰⁴⁵⁵⁶, Su(var)3-9¹⁷ or E(z)⁷³¹,

is dominantly enhanced by Rbf¹⁴, but is not enhanced by trx^unspecified

or ash1^unspecified.

The eye tumour phenotype of flies expressing Dl^Scer\UAS.cDa under

the control of Scer\GAL4^ey.PH and also carrying the P{GSV1}lola^GS88A8

insertion (which results in the lola^GS88A8 and psq^GS88A8 alleles

being expressed under the control of Scer\GAL4^ey.PH) is suppressed

by co-expression of Rbf^Scer\UAS.cDa.

(Ferres-Marco et al., 2006)

Co-misexpression of mib1^{Scer\UAS.T:Zzzz\His6,T:Hsap\MYC} with Dl^Scer\UAS.cDa along the anteroposterior compartment boundary of the wing disc, under the control of Scer\GAL4^dpp.blk1, results in increased ventral disc overgrowth and ectopic wing margins that span the ventral compartment. Co-misexpression of mib1^{ΔRF.Scer\UAS.T:Zzzz\His6,T:Hsap\MYC} with Dl^Scer\UAS.cDa along the anteroposterior compartment boundary of the wing disc using Scer\GAL4^dpp.blk1 completely suppresses the ectopic margin and disc overgrowth seen with Dl^Scer\UAS.cDa expression alone. The expression of Dl^Scer\UAS.cDa is unable to rescue the loss of endogenous wing margin induced by mib1^{ΔRF.Scer\UAS.T:Zzzz\His6,T:Hsap\MYC}.

(Lai et al., 2005)

Flies overexpressing Dl^Scer\UAS.cDa under the control of Scer\GAL4^ey.PH that are also eyg^PxA1/eyg^XE119 mutants have eyes that are reduced in size or completely lack eyes altogether.

(Dominguez et al., 2004)

Co-expression of both Dl^Scer\UAS.cDa and ed^Ext.Scer\UAS under the control of Scer\GAL4^Eq1 significantly increases the density of microchaetae on the adult thorax (the increase is greater than an additive combination of the phenotypes seen when Dl^Scer\UAS.cDa or ed^Ext.Scer\UAS are expressed singly using Scer\GAL4^Eq1).

(Ahmed et al., 2003)

The addition of N^l1N-ts1 (with an associated growth at the restrictive temperature of 29^oC) to Dl^Scer\UAS.cDa/Scer\GAL4^ap-md544 flies completely restores the wild-type pattern of leg segmentation. It also partially restores the basal cylinder phenotype seen in Dl^Scer\UAS.cDa/Scer\GAL4^ap-md544 flies.

(Mishra et al., 2001)

Expression of Dl^Scer\UAS.cDa under the control of Scer\GAL4^32B suppresses the extra wing vein phenotype of nmo^unspecified flies.

(Verheyen et al., 2001)

Expression of Dl^Scer\UAS.cDa under the control of Scer\GAL4^btl.PS does not rescue tracheal dorsal trunk formation in arm⁴ embryos.

(Chihara and Hayashi, 2000)

N^l1N-ts1 ovarioles expressing Dl^Scer\UAS.cDa under the control of Scer\GAL4^hs.PB have the same phenotype as N^l1N-ts1 ovarioles; no stalk cells are produced.

(Larkin et al., 1999)

Dl^Scer\UAS.cDa interacts synergistically with bib^Scer\UAS.cDa producing frequent hair-to-socket transformations when they are expressed using Scer\GAL4^sca-537.4 or Scer\GAL4^sca-109-68.

(Doherty et al., 1997)

Ectopic wing margin is also formed in both dorsal and ventral cells of the wing when Dl^Scer\UAS.cDa is expressed using Scer\GAL4^ptc-559.1 in a fng^D4 background. Ectopic wing margin is formed in ventral cells of the wing when Dl^Scer\UAS.cDa and fng^Scer\UAS.cKa are co-expressed in the wing using Scer\GAL4^ptc-559.1.

(Panin et al., 1997)

Xenogenetic Interactions

Statement

Reference

Co-expression of Mmus\Atoh1^Scer\UAS.cQa almost completely suppresses the formation of eye tumours seen in 'eyeful' (Scer\GAL4^ey.PH, Dl^Scer\UAS.cDa, psq^GS88A8, lola^GS88A8) flies.

(Bossuyt et al., 2009)

Complementation and Rescue Data

Partially rescues

Scer\GAL4^btl.PS/Delta^UAS.cDa partially rescues Delta^vi1/Delta^6B

(Crowner et al., 2003)

Fails to rescue

Delta^UAS.cDa/Scer\GAL4^sim.P3.7 fails to rescue Delta^vi1/Delta^6B

(Crowner et al., 2003)

Comments

The addition of Dl^Scer\UAS.cDa driven by Scer\GAL4^btl.PS largely rescues the ISNb bypass phenotype seen in Dl^6B/Dl^vi1 animals. (6% bypass in rescued embryos versus 23% in N^l1N-ts1 and 3% in wild-type). The addition of Scer\GAL4^sim.P3.7 driven by Scer\GAL4^btl.PS does not rescue the ISNb bypass phenotype seen in Dl^6B/Dl^vi1 animals.

(Crowner et al., 2003)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Construct originally made by E Giniger.

(Crowner et al., 2003, Giniger, 2003.7.28)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Delta^UAS.cDa

Dl^Scer\UAS.cDa

Dl^UAS.cDa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Doherty

(Doherty et al., 1996)

Secondary FlyBase IDs

References (70)

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