Allele Scer\GAL4^c306

General Information
Symbol	Scer\GAL4^c306	Species	S. cerevisiae
Name		FlyBase ID	FBal0048787
Feature type	allele	Associated gene	Scer\GAL4

Allele class
Mutagen
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{GawB}c306 (Lee et al., 1996, McDonald et al., 2003, Silver et al., 2005, Silver and Montell, 2001, Seroude, 2002, Bai and Montell, 2002, Bai et al., 2000, Verkhusha et al., 1999, Adam and Montell, 2004, Pinheiro and Montell, 2004, Loureiro et al., 2001, Manseau et al., 1997, Geisbrecht et al., 2008, McDonald et al., 2008, Jang et al., 2009, Assaker et al., 2010, Laflamme et al., 2012, Furriols et al., 2007, Dornier et al., 2012, Wang et al., 2006)
Cytology
Phenotypic Data
Phenotypic Class
	cell migration defective, with CG4552^GD11348 (Laflamme et al., 2012) cell migration defective, with CG4552^KK101438 (Laflamme et al., 2012) cell migration defective, with CG8155^GD13821 (Laflamme et al., 2012) cell migration defective, with CG8155^KK100131 (Laflamme et al., 2012) cell migration defective, with Evi5^GD6735 (Laflamme et al., 2012) cell migration defective, with Evi5^KK102267 (Laflamme et al., 2012) cell migration defective, with Rab3-GAP^GD12118 (Laflamme et al., 2012) cell migration defective, with Rab3-GAP^KK101062 (Laflamme et al., 2012) cell migration defective, with Rab11^{S25N.Scer\UAS} (Laflamme et al., 2012) cell migration defective, with RN-tre^GD12373 (Laflamme et al., 2012) cell migration defective, with RN-tre^KK102661 (Laflamme et al., 2012) cell migration defective, with Scer\GAL4^slbo.2.6, kuz^KK103555 (Dornier et al., 2012) decreased cell number, with Scer\GAL4^slbo.2.6, kuz^KK103555 (Dornier et al., 2012)
Phenotype Manifest In
	border follicle cell, with ab^EY09709 (Jang et al., 2009) border follicle cell, with baz^GD1384 (McDonald et al., 2008) border follicle cell, with baz^{S151A.S1085A.Scer\UAS.P\T.T:Avic\GFP} (McDonald et al., 2008) border follicle cell, with baz^{Scer\UAS.P\T.T:Avic\GFP} (McDonald et al., 2008) border follicle cell, with CG4552^GD11348 (Laflamme et al., 2012) border follicle cell, with CG4552^KK101438 (Laflamme et al., 2012) border follicle cell, with CG8155^GD13821 (Laflamme et al., 2012) border follicle cell, with CG8155^KK100131 (Laflamme et al., 2012) border follicle cell, with Evi5^GD6735 (Laflamme et al., 2012) border follicle cell, with Evi5^KK102267 (Laflamme et al., 2012) border follicle cell, with hop^Tum.Scer\UAS (Silver et al., 2005) border follicle cell, with Mmmm\ralA^N28.Scer\UAS (Lee et al., 1996) border follicle cell, with Mmmm\ras^N17.Scer\UAS (Lee et al., 1996) border follicle cell, with os^Scer\UAS.cZa (Silver and Montell, 2001) border follicle cell, with par-1^27C1, par-1^{dsRNA.Scer\UAS.cMDa} (McDonald et al., 2008) border follicle cell, with par-1^70D3, par-1^{dsRNA.Scer\UAS.cMDa} (McDonald et al., 2008) border follicle cell, with par-1^{dsRNA.Scer\UAS.cMDa} (McDonald et al., 2008) border follicle cell, with par-1^Δ-16, par-1^{dsRNA.Scer\UAS.cMDa} (McDonald et al., 2008) border follicle cell, with Rab3-GAP^GD12118 (Laflamme et al., 2012) border follicle cell, with Rab3-GAP^KK101062 (Laflamme et al., 2012) border follicle cell, with Rab11^{S25N.Scer\UAS} (Laflamme et al., 2012) border follicle cell, with Rab11^VDRC.cUa (Assaker et al., 2010) border follicle cell, with Ras85D^N17.Scer\UAS (Lee et al., 1996) border follicle cell, with RN-tre^GD12373 (Laflamme et al., 2012) border follicle cell, with RN-tre^KK102661 (Laflamme et al., 2012) border follicle cell, with Scer\GAL4^slbo.2.6, kuz^KK103555 (Dornier et al., 2012) border follicle cell, with sec5^GD13789 (Assaker et al., 2010) border follicle cell, with sec6^VDRC.cUa (Assaker et al., 2010) border follicle cell, with sec8^VDRC.cUa (Assaker et al., 2010) border follicle cell, with sec15^VDRC.cUa (Assaker et al., 2010) border follicle cell, with Socs36E^{Scer\UAS.P\T.cCa} (Silver et al., 2005) border follicle cell, with Socs36E^{ΔSB.Scer\UAS.P\T} (Silver et al., 2005) border follicle cell \| ectopic, with hop^Scer\UAS.cHa (Silver and Montell, 2001) border follicle cell \| ectopic, with hop^Tum.Scer\UAS (Silver and Montell, 2001) border follicle cell \| ectopic, with os^Scer\UAS.cZa (Silver and Montell, 2001) egg chamber, with emc^EP415 (Adam and Montell, 2004) egg chamber, with emc^EP3620 (Adam and Montell, 2004) egg chamber, with emc^{Scer\UAS.cdCa} (Adam and Montell, 2004)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Scer\GAL4^c306/Evi5^{Scer\UAS.T:Disc\RFP-mCherry} rescues Evi5^GD6735 (Laflamme et al., 2012) Scer\GAL4^c306/tai^Scer\UAS.cBa rescues tai^61G1 (Bai et al., 2000, Jang et al., 2009)
Partially rescues	Scer\GAL4^c306/tai^ΔB.Scer\UAS partially rescues tai^61G1 (Jang et al., 2009)
Fails to rescue	Scer\GAL4^c306/Evi5^{R160A.Scer\UAS.T:Disc\RFP-mCherry} fails to rescue Evi5^GD6735 (Laflamme et al., 2012) Scer\GAL4^c306/tai^{bHLH.Scer\UAS.T:Zzzz\FLAG,T:Uuuu\nls6} fails to rescue tai^61G1 (Jang et al., 2009) Scer\GAL4^c306/tai^{PAS.Scer\UAS.T:Zzzz\FLAG,T:Uuuu\nls6} fails to rescue tai^61G1 (Jang et al., 2009) tai^{BP.Scer\UAS.T:Zzzz\FLAG,T:Uuuu\nls6}/Scer\GAL4^c306 fails to rescue tai^61G1 (Jang et al., 2009) tai^{LXXLL.Scer\UAS.T:Avic\GFP,T:Uuuu\nls6}/Scer\GAL4^c306 fails to rescue tai^61G1 (Jang et al., 2009)
Comments
Stocks ( 2 )
Bloomington	3743 P{GawB}c306, w¹¹¹⁸
Kyoto	107215 P{GawB}c306, w¹¹¹⁸
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	GAL4^c306 Scer\GAL4^c306
Name Synonym
Secondary FlyBase IDs

References ( 20 )
Research paper	Dornier et al., 2012, J. Cell Biol. 199(3): 481--496 TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammals. [FBrf0219816] Laflamme et al., 2012, J. Cell Biol. 198(1): 57--67 Evi5 promotes collective cell migration through its Rab-GAP activity. [FBrf0218839] Assaker et al., 2010, Proc. Natl. Acad. Sci. U.S.A. 107(52): 22558--22563 Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration. [FBrf0212585] Jang et al., 2009, Nat. Cell Biol. 11(5): 569--579 Border-cell migration requires integration of spatial and temporal signals by the BTB protein Abrupt. [FBrf0207765] Geisbrecht et al., 2008, Dev. Biol. 314(1): 137--149 Drosophila ELMO/CED-12 interacts with Myoblast city to direct myoblast fusion and ommatidial organization. [FBrf0202723] McDonald et al., 2008, Curr. Biol. 18(21): 1659--1667 PAR-1 Kinase Regulates Epithelial Detachment and Directional Protrusion of Migrating Border Cells. [FBrf0206227] Furriols et al., 2007, Proc. Natl. Acad. Sci. U.S.A. 104(28): 11660--11665 Two distinct but convergent groups of cells trigger Torso receptor tyrosine kinase activation by independently expressing torso-like. [FBrf0201744] Wang et al., 2006, Dev. Cell 10(4): 483--495 Analysis of cell migration using whole-genome expression profiling of migratory cells in the Drosophila ovary. [FBrf0190227] Silver et al., 2005, Development 132(15): 3483--3492 Requirement for JAK/STAT signaling throughout border cell migration in Drosophila. [FBrf0187483] Adam and Montell, 2004, Development 131(23): 5971--5980 A role for extra macrochaetae downstream of Notch in follicle cell differentiation. [FBrf0180182] Pinheiro and Montell, 2004, Development 131(21): 5243--5251 Requirement for Par-6 and Bazooka in Drosophila border cell migration. [FBrf0180163] McDonald et al., 2003, Development 130(15): 3469--3478 PVF1, a PDGF/VEGF homolog, is sufficient to guide border cells and interacts genetically with Taiman. [FBrf0160786] Bai and Montell, 2002, Development 129(23): 5377--5388 Eyes Absent, a key repressor of polar cell fate during Drosophila oogenesis. [FBrf0151937] Seroude, 2002, genesis 34(1-2): 34--38 GAL4 drivers expression in the whole adult fly. [FBrf0152373] Loureiro et al., 2001, Dev. Biol. 235(1): 33--44 Activated armadillo/beta-catenin does not play a general role in cell migration and process extension in Drosophila. [FBrf0136851] Silver and Montell, 2001, Cell 107(7): 831--841 Paracrine Signaling through the JAK/STAT Pathway Activates Invasive Behavior of Ovarian Epithelial Cells in Drosophila. [FBrf0141417] Bai et al., 2000, Cell 103(7): 1047--1058 Regulation of invasive cell behavior by taiman, a Drosophila protein related to AIB1, a steroid receptor coactivator amplified in breast cancer. [FBrf0132259] Verkhusha et al., 1999, FEBS Lett. 445(2-3): 395--401 Actin dynamics in lamellipodia of migrating border cells in the Drosophila ovary revealed by a GFP-actin fusion protein. [FBrf0108052] Manseau et al., 1997, Dev. Dyn. 209(3): 310--322 GAL4 enhancer traps expressed in the embryo, larval brain, imaginal discs, and ovary of Drosophila. [FBrf0095642] Lee et al., 1996, Development 122(2): 409--418 Two distinct roles for Ras in a developmentally regulated cell migration. [FBrf0088383]

Allele Scer\GAL4c306

Allele Scer\GAL4^c306