FlyBase Allele Report: Scer\GAL4[c739]

ScerGAL4^NP0385 drives expression in neurons with cell bodies located lateral to the antennal lobes (AL). Some of the labeled neurons innervate the AL.

(Thum et al., 2011)

ScerGAL4^c739 labels the mushroom body alpha/beta neurons. Co-expression with presynaptic and postsynaptic markers labels distinct domains of Kenyon cell terminals in the calyx of the mushroom body.

(Christiansen et al., 2011)

ScerGAL4^c739 is expressed in a subset of cells in the adult brain, including the mushroom body alpha/beta neurons.

(Lee et al., 2011)

ScerGAL4^c739 drives expression in approximately 16 columnar neurons in the superior medial protocerebrum that innervate the fan shaped body.

(Kahsai et al., 2010)

Expression is limited to alpha and beta neurons in the adult mushroom body.

(Blum et al., 2009)

Expression of ScerGAL4^c739 is not evident in the alpha'-lobes, the beta'-lobes, or the gamma-lobes.

(Krashes et al., 2007)

In early larval stages ScerGAL4^c739 is widely expressed in most of the Kenyon cells, and is seen throughout most axons of the pedunculus and mushroom body lobes in a pattern similar to Fas2. By third instar, expression becomes restricted to a small group of cells near each neuroblast whose projections pass through the inner layer of the pedunculus and lobes.

(Kurusu et al., 2002)

Expression of ScerGAL4^c739 in the alpha- and beta-lobes of the mushroom body is restricted in early and mid-pupal stages, but becomes extensive from late-pupal stage onwards. Gamma-lobe expression is extensive in mid-pupal stage, but is reduced by late-pupal stage and lost in adults.

(Armstrong et al., 1998)

In third instar larva, expression in central brain; in 2 longitudinal stripes in the ventral ganglion; in the pouch region of the wing and haltere discs; little or no expression in other discs.

(Manseau et al., 1997)

Larval expression is observed in subset of Kenyon cells in each of four clusters, in the calyx, and the in the circumference of the pedunculus. In the second and third larval instars, expression is also observed in the cores of the α, α', β and γ lobes of the mushroom body.

(Tettamanti et al., 1997)

Marker for

adult mushroom body beta-lobe

(Mao and Davis, 2009)

alpha/beta Kenyon cell

(Christiansen et al., 2011, Lee et al., 2011)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal courtship behavior | male, with tra^UAS.cFa

(O'Dell et al., 1995)

abnormal heat stress response, with Pgam5^NIG.14816R

(Ishida et al., 2012)

abnormal learning, with drk^RNAi.Sym.UAS

(Moressis et al., 2009)

abnormal learning, with Ent2^GD953

(Knight et al., 2010)

abnormal learning, with Ras85D^V12.UAS

(Moressis et al., 2009)

abnormal learning, with Rdl^RNAi.2-7.UAS

(Liu et al., 2009)

abnormal learning, with Rdl^{RNAi.8-10.UAS}

(Liu et al., 2007)

abnormal learning, with sra^UAS.Tag:HA

(Chang et al., 2003)

abnormal locomotor behavior | adult stage, with Tk^RNAi.UAS.cWa

(Kahsai et al., 2010)

abnormal locomotor behavior | adult stage | heat sensitive, with shi^1.UAS

(Kahsai et al., 2010)

abnormal long-term memory, with uex^HMS01492

(Wu et al., 2020)

abnormal medium-term memory | adult stage, with 5-HT1A^KK108407

(Muria et al., 2021)

abnormal medium-term memory | adult stage | :heat sensitive | conditional, with shi^ts.UAS.cUa

(Muria et al., 2021)

abnormal memory, with 5-HT1A^KK108407

(Lee et al., 2011)

abnormal memory, with 5-HT1A^KK108407, Scer\GAL80^ts.αTub84B

(Lee et al., 2011)

abnormal memory, with Bper\ptxA^act.UAS

(Ferris et al., 2006)

abnormal memory, with brp^RNAi.B.UAS, brp^RNAi.C.UAS

(Knapek et al., 2011)

abnormal memory, with CrebB^b.UAS

(Chen et al., 2012, Yu et al., 2006)

abnormal memory, with hiw^ΔRING.UAS

(Huang et al., 2012)

abnormal memory, with scrib^KK106065

(Cervantes-Sandoval et al., 2016)

abnormal memory, with shi^1.UAS

(Tonoki and Davis, 2015)

abnormal memory | adult stage, with Appl^{Aβ.UAS.Tag:HA}

(Turrel et al., 2017)

abnormal memory | adult stage, with Dop1R1^HMC02344

(Ichinose et al., 2015)

abnormal memory | adult stage, with DopEcR^KK111211

(Ishimoto et al., 2013)

abnormal memory | adult stage, with hop^RNAi.UAS.cCa

(Copf et al., 2011)

abnormal memory | adult stage, with Hsap\APP^{695.UAS.Tag:MYC}

(Shaw et al., 2015)

abnormal memory | adult stage, with Hsap\MAPT^R406W.UAS

(Haddadi et al., 2016)

abnormal memory | adult stage, with Hsap\MAPT^UAS.cWa

(Haddadi et al., 2016)

abnormal memory | adult stage, with Hsap\MAPT^V337M.UAS

(Haddadi et al., 2016)

abnormal memory | adult stage, with Inx5^GD1177

(Shyu et al., 2019)

abnormal memory | adult stage, with Nep1^GD11797

(Turrel et al., 2017)

abnormal memory | adult stage, with Pde4^RNAi.UAS.WIZ

(Bouzaiane et al., 2015)

abnormal memory | adult stage, with Rgk1^RNAi.UAS

(Murakami et al., 2017)

abnormal memory | adult stage, with shi^1.UAS

(Krashes et al., 2007)

abnormal memory | adult stage, with sra^JF02557

(Shaw et al., 2015)

abnormal memory | adult stage, with sra^UAS.Tag:HA

(Shaw et al., 2015)

abnormal memory | adult stage, with tau^RNAi.UAS

(Papanikolopoulou et al., 2019)

abnormal memory | adult stage, with tau^{UAS.A.Tag:FLAG}

(Papanikolopoulou et al., 2019)

abnormal memory | adult stage | conditional, with Npha\HR^{eNpHR(Unk).UAS.YFP.cUa}

(Shyu et al., 2019)

abnormal memory | adult stage | heat sensitive, with Scer\GAL4^5-HT1B.PY, shi^1.UAS

(Xie et al., 2013)

abnormal memory | adult stage | heat sensitive, with Scer\GAL4^VT030604, shi^1.UAS

(Yang et al., 2016)

abnormal memory | adult stage | heat sensitive, with Scer\GAL80^ChAT.3.3P, shi^1.UAS

(Perisse et al., 2013)

abnormal memory | adult stage | heat sensitive, with shi^1.UAS

(Yang et al., 2016, Bouzaiane et al., 2015, Ichinose et al., 2015, Perisse et al., 2013, Xie et al., 2013, Zhang et al., 2013)

abnormal memory | adult stage | heat sensitive, with shi^{ts1.IVS.p10.20xUAS}

(Shyu et al., 2017)

abnormal memory | heat sensitive, with shi^1.UAS

(Isabel et al., 2004, McGuire et al., 2001)

abnormal neuroanatomy, with CrebB^b.UAS

(Chen et al., 2012)

abnormal neuroanatomy, with EcR^RNAi.UAS.cCa

(Kucherenko et al., 2012)

abnormal neuroanatomy, with Mtch^UY627

(Nicolai et al., 2003)

abnormal neuroanatomy, with RN-tre^UY333

(Nicolai et al., 2003)

abnormal neuroanatomy, with ttk^p69.UAS

(Nicolai et al., 2003)

abnormal neuroanatomy, with ttk^UY181

(Nicolai et al., 2003)

abnormal neuroanatomy, with UY2635^UY2635

(Nicolai et al., 2003)

abnormal neuroanatomy, with Wnt5^UAS.cFa

(Reynaud et al., 2015)

abnormal neuroanatomy | adult stage, with Fas2^UAS.cLa

(Fushima and Tsujimura, 2007)

abnormal neuroanatomy | adult stage, with Graf^HMC03427

(Kim et al., 2021)

abnormal neuroanatomy | larval stage, with Fas2^UAS.cLa

(Fushima and Tsujimura, 2007)

abnormal neuroanatomy | pupal stage, with Fas2^UAS.cLa

(Fushima and Tsujimura, 2007)

abnormal neuroanatomy | third instar larval stage, with Dsk^GD6123

(Chen and Ganetzky, 2012)

abnormal neurophysiology | heat sensitive, with shi^1.UAS

(van Swinderen et al., 2009)

abnormal size, with sd^KK108877

(Rohith and Shyamala, 2017)

abnormal size | adult stage, with Fas2^UAS.cLa

(Fushima and Tsujimura, 2007)

abnormal sleep | adult stage, with Nf1^KK101909

(Machado Almeida et al., 2021)

abnormal visual behavior | heat sensitive, with shi^1.UAS

(van Swinderen et al., 2009)

decreased efficacy of long-term memory | adult stage, with milt^HMC02365

(Pavlowsky et al., 2024)

decreased efficacy of long-term memory | adult stage, with Miro^JF02775

(Pavlowsky et al., 2024)

lethal, with Hsap\TMEM63B^{G580C.UAS.Tag:MYC}

(Vetro et al., 2023)

lethal, with Hsap\TMEM63B^{V44M.UAS.Tag:MYC}

(Vetro et al., 2023)

lethal, with mys^RNAi.Sym.UAS

(Bhandari et al., 2006)

viable, with UY2635^UY2635

(Nicolai et al., 2003)

visible | male limited, with tra^{mw(-).UAS.cFa}

(An et al., 2000)

visible | male limited, with tra^UAS.cFa

(An et al., 2000)

Phenotype Manifest In

abdomen | male, with tra^UAS.cFa

(O'Dell et al., 1995)

abdominal segment 1, with Abd-B^UAS.cCa

(Casares et al., 1996)

abdominal segment 1, with Scer\GAL4^C-765, abd-A^1dB5.UAS

(Casares et al., 1996)

adult external abdomen, with tra^{mw(-).UAS.cFa}

(An et al., 2000)

adult external abdomen, with tra^UAS.cFa

(An et al., 2000)

adult mushroom body, with CrebB^b.UAS

(Chen et al., 2012)

adult mushroom body, with Mtch^UY627

(Nicolai et al., 2003)

adult mushroom body, with RN-tre^UY333

(Nicolai et al., 2003)

adult mushroom body, with ttk^p69.UAS

(Nicolai et al., 2003)

adult mushroom body, with ttk^UY181

(Nicolai et al., 2003)

adult mushroom body alpha'-lobe, with Fas2^UAS.cLa

(Fushima and Tsujimura, 2007)

adult mushroom body alpha'-lobe | pupal stage, with Fas2^UAS.cLa

(Fushima and Tsujimura, 2007)

adult mushroom body alpha-lobe, with Fas2^UAS.cLa

(Fushima and Tsujimura, 2007)

adult mushroom body alpha-lobe, with Wnt5^UAS.cFa

(Reynaud et al., 2015)

adult mushroom body alpha-lobe | pupal stage, with Fas2^UAS.cLa

(Fushima and Tsujimura, 2007)

adult mushroom body beta-lobe, with EcR^RNAi.UAS.cCa

(Kucherenko et al., 2012)

adult mushroom body beta-lobe, with Fas2^UAS.cLa

(Fushima and Tsujimura, 2007)

adult mushroom body beta-lobe, with Graf^HMC03427

(Kim et al., 2021)

adult mushroom body beta-lobe, with UY2635^UY2635

(Nicolai et al., 2003)

axon | adult stage, with Graf^HMC03427

(Kim et al., 2021)

embryonic/larval neuromuscular junction | third instar larval stage, with Dsk^GD6123

(Chen and Ganetzky, 2012)

Kenyon cell, with Mtch^UY627

(Nicolai et al., 2003)

Kenyon cell, with RN-tre^UY333

(Nicolai et al., 2003)

Kenyon cell, with sd^KK108877

(Rohith and Shyamala, 2017)

Kenyon cell, with ttk^p69.UAS

(Nicolai et al., 2003)

Kenyon cell, with ttk^UY181

(Nicolai et al., 2003)

Kenyon cell, with UY2635^UY2635

(Nicolai et al., 2003)

lobe system of adult mushroom body, with EcR^RNAi.UAS.cCa

(Kucherenko et al., 2012)

male genitalia, with tra^UAS.cFa

(O'Dell et al., 1995)

medial lobe of adult mushroom body, with Fas2^UAS.cLa

(Fushima and Tsujimura, 2007)

midline | adult stage, with Graf^HMC03427

(Kim et al., 2021)

mushroom body, with sd^KK108877

(Rohith and Shyamala, 2017)

mushroom body & axon, with Mtch^UY627

(Nicolai et al., 2003)

mushroom body & axon, with RN-tre^UY333

(Nicolai et al., 2003)

mushroom body & axon, with UY2635^UY2635

(Nicolai et al., 2003)

NMJ bouton | third instar larval stage, with Dsk^GD6123

(Chen and Ganetzky, 2012)

pedunculus of adult mushroom body, with Fas2^UAS.cLa

(Fushima and Tsujimura, 2007)

pedunculus of larval mushroom body, with Fas2^UAS.cLa

(Fushima and Tsujimura, 2007)

salivary gland, with Hsf^UAS.GFP

(Salamanca et al., 2011)

Detailed Description

Statement

Reference

Blockade of all αβ Kenyon cells (by expressing the temperature sensitive shi^ts.UAS.cUa under the control of Scer\GAL4^c739 and shifted to the permissive 33[o]C) decreases olfactory medium term memory (1h) when experiment is carried out in crowded conditions (groups of 32 flies - socially facilitated memory).

(Muria et al., 2021)

Inhibition (using shi^1.UAS at 32[o]C) of Scer\GAL4^c739 cells during acquisition and consolidation does not affect the residual anaesthesia-resistant 3 hour aversive olfactory memory after cold-shock, compared to controls.

Hyperpolarization (using Npha\HR^{eNpHR(Unk).UAS.YFP.cUa} with 590 nm (yellow) light) of Scer\GAL4^c739 cells in adults during testing, but not during training or consolidation, significantly reduces the residual anaesthesia-resistant 3 hour aversive olfactory memory after cold-shock, compared to controls.

(Shyu et al., 2019)

Inhibition (using shi^{ts1.IVS.p10.20xUAS} at 32[o]C) of Scer\GAL4^c739 cells in adults during retrieval alone, but not acquisition and consolidation, significantly reduces 24-hour associative olfactory water-reward memory, compared to controls; inhibition has no effect on odor acuity or water preference, compared to controls.

(Shyu et al., 2017)

Inhibition (using shi^1.UAS at 31[o]C) of Scer\GAL4^c739 cells in adults during testing only significantly reduces 3-hour aversive olfactory anaesthesia-resistant memory (ARM), compared to controls; ARM is further reduced when Scer\GAL4^c739 and Scer\GAL4^VT030604 cells are simultaneously inhibited during testing, with no effect on odor or shock avoidance, compared to controls.

(Yang et al., 2016)

Inhibition (using shi^1.UAS at 33[o]C) of Scer\GAL4^c739 cells in adults significantly reduces short term (5 min) aversive olfactory memory, including its anaesthesia-resistant component, compared to controls; inhibition during testing significantly reduces medium term (2 h or 3 h), aversive olfactory memory, but not its anaesthesia-resistant component, with no effect on long term (24 h after massed training) memory, compared to controls.

(Bouzaiane et al., 2015)

Inhibition (using shi^1.UAS at 32[o]C) of Scer\GAL4^c739 neurons in adults during, or immediately after, training, but not immediately before testing, significantly impairs long-term appetitive olfactory memory, compared to controls; inhibition does not affect short-term memory.

(Ichinose et al., 2015)

Inhibition (using shi^1.UAS at 32[o]C) of Scer\GAL4^c739 cells in adults does not affect 5 min (single-trial conditioned) or 30 min (multiple-trial conditioned) aversive taste memory, compared to controls.

(Kirkhart and Scott, 2015)

Blocking synaptic transmission (using shi^1.Scer\UAS at restrictive temperatures) from Scer\GAL4^c739 neurons significantly impairs sucrose-reinforced appetitive memory performance (at 2, 3 or 24 hours but not at 30 minutes since training) compared to controls. Blocking synaptic transmission from Scer\GAL4^c739 neurons significantly impairs electric-shock-reinforced aversive memory performance (at 3hrs) compared to controls. Blocking synaptic transmission from Scer\GAL4^c739/Scer\GAL80^ChAT.3.3P neurons significantly impairs sucrose-reinforced appetitive memory (3hr), but not electric-shock-reinforced aversive memory (3hr), compared to controls. Blocking synaptic transmission from Scer\GAL4^c739/Scer\GAL80^ChAT.3.3P neurons during testing (30min since conditioning) significantly impairs memory in a differential aversive conditioning paradigm (in the Y[[60]] vs Z[[30]] relative condition but not the X[[0]] vs Y[[60]] absolute condition). Flies undergo conditioning at a permissive temperature (23[o]C), whereas testing is at a restrictive temperature (33[o]C); there are no significant memory differences when training and testing is at permissive temperatures. Scer\GAL4^c739>shi^1.Scer\UAS flies exhibit normal olfactory acuity at the restrictive temperature.

(Perisse et al., 2013)

Inhibition (using shi^1.UAS at 33[o]C) of Scer\GAL4^c739 cells in adults during testing significantly reduces 3 min, 1 h and 3 h aversive or appetitive olfactory memory, compared to controls; reduction in 3 h aversive or appetitive memory, and 1 h appetitive memory, is no longer seen when inhibition is restricted to a smaller subset of Scer\GAL4^c739 cells using Scer\GAL80^Mef2.mb247; inhibition of the combined set of Scer\GAL4^5-HT1B.PY cells and Scer\GAL4^c739 significantly reduces 3 h and 3 min aversive or appetitive memory, compared to controls; inhibition of Scer\GAL4^c739 cells has no effect on naive preferences for odors, shock or sugar, compared to controls.

(Xie et al., 2013)

Inhibition (using shi^1.UAS at 31[o]C) of Scer\GAL4^c739 cells in adults significantly reduces short-term aversive olfactory, but not visual, unimodal memory, compared to controls; inhibition significantly reduces short-term aversive memory for tested olfactory cues that are associated with conditioned visual cues, compared to controls.

(Zhang et al., 2013)

Blocking synaptic transmission in Scer\GAL4^c739-expressing neurons for the 12 hour interval 6 hours after spaced training impairs aversive long term memory.

Sensorimotor abilities are impaired when synaptic transmission is blocked in Scer\GAL4^c739-expressing neurons when compared to controls without the driver, but is not significantly different from the driver only controls.

Blocking synaptic transmission in Scer\GAL4^c739-expressing neurons during the post-training period impairs appetitive long term memory (association of an odor with sucrose). Sensorimotor abilities are unchanged compared with controls.

(Huang et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^c739, Wnt5^UAS.cFa has abnormal neuroanatomy phenotype, enhanceable by drl[+]/drl²

(Reynaud et al., 2015)

Scer\GAL4^c739, Wnt5^UAS.cFa has abnormal neuroanatomy phenotype, enhanceable by Drl-2^E124/Drl-2[+]

(Reynaud et al., 2015)

Scer\GAL4^c739, Wnt5^UAS.cFa has abnormal neuroanatomy phenotype, enhanceable by drl[+]/drl²/Drl-2^E124/Drl-2[+]

(Reynaud et al., 2015)

NOT Enhanced by

Statement

Reference

Nep1^GD11797, Scer\GAL4^c739 has abnormal memory | adult stage phenotype, non-enhanceable by Appl^{Aβ.UAS.Tag:HA}, Scer\GAL4^c739

(Turrel et al., 2017)

Scer\GAL4^c739, sra^JF02557 has abnormal memory | adult stage phenotype, non-enhanceable by Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^c739

(Shaw et al., 2015)

Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^c739 has abnormal memory | adult stage phenotype, non-enhanceable by sra^JF02557, Scer\GAL4^c739

(Shaw et al., 2015)

Suppressed by

Statement

Reference

Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^c739 has abnormal memory | adult stage phenotype, suppressible | partially by CanB^JF02616, Scer\GAL4^c739

(Shaw et al., 2015)

Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^c739 has abnormal memory | adult stage phenotype, suppressible | partially by Pka-C1^UAS.Tag:FLAG, Scer\GAL4^c739

(Shaw et al., 2015)

Scer\GAL4^c739, sra^UAS.Tag:HA has abnormal memory | adult stage phenotype, suppressible | partially by Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^c739

(Shaw et al., 2015)

NOT suppressed by

Statement

Reference

Appl^{Aβ.UAS.Tag:HA}, Scer\GAL4^c739 has abnormal memory | adult stage phenotype, non-suppressible by Nep1^EY21255, Scer\GAL4^c739

(Turrel et al., 2017)

Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^c739 has abnormal memory | adult stage phenotype, non-suppressible by sra^JF02557, Scer\GAL4^c739

(Shaw et al., 2015)

Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^c739 has abnormal memory | adult stage phenotype, non-suppressible by sgg¹

(Shaw et al., 2015)

Scer\GAL4^c739, sra^JF02557 has abnormal memory | adult stage phenotype, non-suppressible by Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^c739

(Shaw et al., 2015)

Enhancer of

Statement

Reference

Scer\GAL4^c739/Bace^UAS.cCSa is an enhancer of abnormal memory | adult stage phenotype of Appl^d

(Bourdet et al., 2015)

shi^1.UAS/Scer\GAL4^c739 is an enhancer of abnormal heat stress response phenotype of Pgam5¹

(Ishida et al., 2012)

NOT Enhancer of

Statement

Reference

Appl^{Aβ.UAS.Tag:HA}, Scer\GAL4^c739 is a non-enhancer of abnormal memory | adult stage phenotype of Nep1^GD11797, Scer\GAL4^c739

(Turrel et al., 2017)

Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^c739 is a non-enhancer of abnormal memory | adult stage phenotype of Scer\GAL4^c739, sra^JF02557

(Shaw et al., 2015)

sra^JF02557, Scer\GAL4^c739 is a non-enhancer of abnormal memory | adult stage phenotype of Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^c739

(Shaw et al., 2015)

Suppressor of

Statement

Reference

Scer\GAL4^c739/Mmus\Cnnm2^UAS.Tag:HA is a suppressor of abnormal long-term memory phenotype of uex^MI01943

(Wu et al., 2020)

CanB^JF02616, Scer\GAL4^c739 is a suppressor | partially of abnormal memory | adult stage phenotype of Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^c739

(Shaw et al., 2015)

Pka-C1^UAS.Tag:FLAG, Scer\GAL4^c739 is a suppressor | partially of abnormal memory | adult stage phenotype of Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^c739

(Shaw et al., 2015)

Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^c739 is a suppressor | partially of abnormal memory | adult stage phenotype of Scer\GAL4^c739, sra^UAS.Tag:HA

(Shaw et al., 2015)

sra^UAS.Tag:HA/Scer\GAL4^c739 is a suppressor of abnormal memory | adult stage phenotype of Hsap\APP^{695.UAS.Tag:MYC}

(Shaw et al., 2015)

BacA\p35^UAS.cHa/Scer\GAL4^c739 is a suppressor of abnormal heat stress response phenotype of Pgam5¹

(Ishida et al., 2012)

Hsap\SLC12A5^UAS.cHa/Scer\GAL4^c739 is a suppressor of paralytic | recessive phenotype of kcc^DHS1

(Hekmat-Scafe et al., 2010)

kcc^UAS.cHb/Scer\GAL4^c739 is a suppressor of paralytic phenotype of para^bss1

(Hekmat-Scafe et al., 2010)

kcc^UAS.cHb/Scer\GAL4^c739 is a suppressor of paralytic phenotype of eas²

(Hekmat-Scafe et al., 2010)

NOT Suppressor of

Statement

Reference

Mmus\Cnnm2^{T568I.UAS.Tag:HA}/Scer\GAL4^c739 is a non-suppressor of abnormal long-term memory phenotype of uex^MI01943

(Wu et al., 2020)

Scer\GAL4^c739/Mmus\Cnnm2^{E357K.UAS.Tag:HA} is a non-suppressor of abnormal long-term memory phenotype of uex^MI01943

(Wu et al., 2020)

Mmus\Cnnm2^{E122K.UAS.Tag:HA}/Scer\GAL4^c739 is a non-suppressor of abnormal long-term memory phenotype of uex^MI01943

(Wu et al., 2020)

Mmus\Cnnm2^{S269W.UAS.Tag:HA}/Scer\GAL4^c739 is a non-suppressor of abnormal long-term memory phenotype of uex^MI01943

(Wu et al., 2020)

Nep1^EY21255, Scer\GAL4^c739 is a non-suppressor of abnormal memory | adult stage phenotype of Appl^{Aβ.UAS.Tag:HA}, Scer\GAL4^c739

(Turrel et al., 2017)

sra^JF02557, Scer\GAL4^c739 is a non-suppressor of abnormal memory | adult stage phenotype of Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^c739

(Shaw et al., 2015)

Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^c739 is a non-suppressor of abnormal memory | adult stage phenotype of Scer\GAL4^c739, sra^JF02557

(Shaw et al., 2015)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^c739, Wnt5^UAS.cFa has adult mushroom body alpha-lobe phenotype, enhanceable by drl[+]/drl²

(Reynaud et al., 2015)

Scer\GAL4^c739, Wnt5^UAS.cFa has adult mushroom body alpha-lobe phenotype, enhanceable by Drl-2^E124/Drl-2[+]

(Reynaud et al., 2015)

Scer\GAL4^c739, Wnt5^UAS.cFa has adult mushroom body alpha-lobe phenotype, enhanceable by drl[+]/drl²/Drl-2^E124/Drl-2[+]

(Reynaud et al., 2015)

Suppressed by

Statement

Reference

Hsf^UAS.GFP, Scer\GAL4^c739 has salivary gland phenotype, suppressible by Zzzz\aptamer^Hsf.X8.UAS/Scer\GAL4^αTub84B.PL

(Salamanca et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

uex^UAS.cWa/Scer\GAL4^c739 rescues uex^MI01943

(Wu et al., 2020)

DopEcR^UAS.cIb/Scer\GAL4^c739 rescues DopEcR^c02142

(Ishimoto et al., 2013)

Pgam5^UAS.cIa/Scer\GAL4^c739 rescues Pgam5¹

(Ishida et al., 2012)

Oamb^UAS.cZa/Scer\GAL4^c739 rescues Oamb^unspecified

(Zhou et al., 2012)

Scer\GAL4^c739/Dop1R1^UAS.cBa rescues Dop1R1^PL00420

(Bang et al., 2011)

Nf1^UAS.cBa/Scer\GAL4^c739 rescues Nf1^c00617

(Buchanan and Davis, 2010)

Nf1^UAS.cBa/Scer\GAL4^c739 rescues Nf1^P1

(Buchanan and Davis, 2010)

be^UAS.cZa/Scer\GAL4^c739 rescues be^P1

(Zhao et al., 2009)

sra^UAS.Tag:HA/Scer\GAL4^c739 rescues sra¹

(Chang et al., 2003)

Partially rescues

Rgk1^UAS.B/Scer\GAL4^c739 partially rescues Rgk1^Δ

(Murakami et al., 2017)

Drl-2^UAS.Tag:MYC/Scer\GAL4^c739 partially rescues Df(2R)Exel8057/Drl-2^E124

(Reynaud et al., 2015)

kcc^UAS.cHb/Scer\GAL4^c739 partially rescues kcc^DHS1

(Hekmat-Scafe et al., 2010)

drl^UAS.cCa/Scer\GAL4^c739 partially rescues drl²/drl^R343

(Moreau-Fauvarque et al., 1998)

Fails to rescue

uex^R622K.UAS/Scer\GAL4^c739 fails to rescue uex^MI01943

(Wu et al., 2020)

Dop2R^UAS.cDa/Scer\GAL4^c739 fails to rescue Dop2R^attP

(Deng et al., 2019)

Nf1^UAS.cdNa/Scer\GAL4^c739 fails to rescue Nf1^P2/Nf1^P1

(Bai et al., 2018)

Nrx-1^UAS.cZa/Scer\GAL4^c739 fails to rescue Nrx-1^Δ83

(Liu et al., 2017)

Dop1R1^f02676/Scer\GAL4^c739 fails to rescue Dop1R1^f02676

(Shyu et al., 2017)

Nab2^UAS.Tag:FLAG/Scer\GAL4^c739 fails to rescue Nab2^ex3

(Kelly et al., 2016)

Scer\GAL80^Mef2.mb247, Drl-2^UAS.Tag:MYC, Scer\GAL4^c739 fails to rescue Df(2R)Exel8057/Drl-2^E124

(Reynaud et al., 2015)

Drl-2^{Δcyto.UAS.Tag:MYC}/Scer\GAL4^c739 fails to rescue Df(2R)Exel8057/Drl-2^E124

(Reynaud et al., 2015)

Dop1R1^UAS.cLa/Scer\GAL4^c739 fails to rescue Dop1R1^f02676

(Lin et al., 2014)

Pgam5^H94A.UAS/Scer\GAL4^c739 fails to rescue Pgam5¹

(Ishida et al., 2012)

Dop1R1^UAS.cKb/Scer\GAL4^c739 fails to rescue Dop1R1^attP

(Keleman et al., 2012)

Scer\GAL4^c739, inc^f00285 fails to rescue inc^f00285

(Stavropoulos and Young, 2011)

gish^UAS.cTa/Scer\GAL4^c739 fails to rescue gish^MB896

(Tan et al., 2010)

orb2^A.UAS/Scer\GAL4^c739 fails to rescue orb2^ΔQ/orb2^Δ

(Keleman et al., 2007)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

7362

y¹ w^67c23; P{GawB}Hr39^c739

64305

y¹ w^67c23; P{GawB}Hr39^c739 P{UAS-mCD8::GFP.L}LL5

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

GAL4^c739

Scer\GAL4^c739

Name Synonyms

Secondary FlyBase IDs

References (183)

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