Allele Dmel\RpS3^unspecified

General Information
Symbol	Dmel\RpS3^unspecified	Species	D. melanogaster
Name		FlyBase ID	FBal0048877
Feature type	allele	Associated gene	Dmel\RpS3

Allele class
Mutagen
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	cell lethal \| recessive (Morris et al., 2008) visible \| dominant (Montagne et al., 1999, Morris et al., 2008)
Phenotype Manifest In
	eye (Morris et al., 2008) macrochaeta (Montagne et al., 1999)
Detailed Description
	Statement Reference Heterozygotes have slightly smaller eyes than normal. (Morris et al., 2008) Heterozygotes show no effect on body size, but are developmentally delayed and have slender bristles. (Montagne et al., 1999)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement Reference RpS3[+]/RpS3^unspecified is a suppressor of large body \| pupal stage phenotype of Maf1^{dsRNA.Scer\UAS}, Scer\GAL4^da.G32 (Rideout et al., 2012) RpS3[+]/RpS3^unspecified is a suppressor of large body \| pupal stage phenotype of tRNA:M-i:61D^+tRa (Rideout et al., 2012)
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference The increase in pupal volume caused by expression of Maf1[dsRNA.Scer\UAS] under the control of Scer\GAL4[da.G32] is suppressed by RpS3[unspecified]/+. The increase in pupal volume caused by tRNA:M-i:61D[+tRa] is suppressed by RpS3[unspecified]/+. (Rideout et al., 2012) Mutants reveal no dosage sensitive maternal modifier effect on run mutant phenotypes. (Duffy et al., 1996)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	RpS3^unspecified unspecified (Duffy et al., 1996)
Name Synonym
Secondary FlyBase IDs

References ( 6 )
Research paper	Rideout et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(4): 1139--1144 Drosophila RNA polymerase III repressor Maf1 controls body size and developmental timing by modulating tRNAiMet synthesis and systemic insulin signaling. [FBrf0217359] Morris et al., 2008, Genetics 178(2): 979--987 Mutations in the Drosophila mitochondrial tRNA amidotransferase, bene/gatA, cause growth defects in mitotic and endoreplicating tissues. [FBrf0204272] Mandal et al., 2005, Dev. Cell 9(6): 843--854 Mitochondrial regulation of cell cycle progression during development as revealed by the tenured mutation revealed in Drosophila. [FBrf0190213] Montagne et al., 1999, Science 285(5436): 2126--2129 Drosophila S6 kinase: A regulator of cell size. [FBrf0111434] de Celis et al., 1996, Development 122(9): 2719--2728 Functional relationships between N, Su(H) and the bHLH genes of the E(spl) complex: the E(spl) genes mediate only a subset of Notch activities during imaginal development. [FBrf0090023] Duffy et al., 1996, Genetics 142(3): 839--852 Dosage-sensitive maternal modifiers of the Drosophila segmentation gene runt. [FBrf0086390]

Allele Dmel\RpS3unspecified

Allele Dmel\RpS3^unspecified