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General Information
Symbol
Dmel\Ptp69D3
Species
D. melanogaster
Name
FlyBase ID
FBal0048916
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Deletion removing N-terminal coding sequences, including the signal sequence, the immunoglobulin domain and at least two of the fibronectin repeats.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Shows incompletely penetrant SNb (and, to a lesser extent, SNa) pathfinding defects. RP axons sometimes exhibit guidance errors within the CNS.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement
Reference

Ptp69D3 has RP neuron & axon phenotype, enhanceable by Ptp99A1

Additional Comments
Genetic Interactions
Statement
Reference

Penetrance and severity of mutant phenotypes is enhanced by Ptp99A1. This enhanced phenotype is completely rescued by one copy of Ptp69D+t10.5. The severity of the RP axon phenotype is enhanced by Ptp99A1.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Rank order for penetrance of SNb mutant phenotypes is Ptp69D1 > Ptp69D2 > Ptp69D1/Ptp69D3 > Ptp69D3.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Ptp69D3
Name Synonyms
Secondary FlyBase IDs
    References (1)