Allele Dmel\Taf1^S-136

General Information
Symbol	Dmel\Taf1^S-136	Species	D. melanogaster
Name		FlyBase ID	FBal0048986
Feature type	allele	Associated gene	Dmel\Taf1
Also Known As	SR3-5^S-136

Map ( GBrowse )
Allele class
Mutagen	ethyl methanesulfonate
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	ethyl methanesulfonate (Karim et al., 1996)
Mutations Mapped to the Genome

Type Location Additional Notes References point mutation 3R:2,476,570..2,476,570 comment=Position of mutation on reference sequence inferred by FlyBase curator based on author statement (Figure 4: DADLRR changes to DANLRR). evidence=experimental na_change=G2476570A pr_change=D1038N\|Taf1-PA,D1038N\|Taf1-PB,D1038N\|Taf1-PC reported_pr_change=D1041N
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Amino acid replacement: D1041N. (Wassarman et al., 2000)
Cytology
Phenotypic Data
Phenotypic Class
	female sterile (Wassarman et al., 2000) lethal \| recessive (Karim et al., 1996)
Phenotype Manifest In
	macrochaeta (Wassarman et al., 2000)
Detailed Description
	Statement Reference Taf1^EP421/Taf1^S-136 flies are have reduced bristle numbers on both male and female heads and are female sterile. (Wassarman et al., 2000)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement Reference Taf1^S-136 is a suppressor of phenotype of Ras85D^V12.sev (Karim et al., 1996)
Additional Comments
Genetic Interactions
Statement Reference Suppresses the rough eye phenotype of Ras85D^V12.sev. Slightly suppresses the phenotype of Ras85D^N17.sev. Has little or no effect on the phenotype of phl::tor^13D.hs.sev. Suppresses the phenotype of Ras85D::Src64B^{V12.ΔCAAX.sev}. Has little or no effect on the lethality of phl¹². Has little or no effect on the phl¹² eye phenotype. Has little or no effect on the Dsor1^XS520 eye phenotype. Has little or no effect on the aop^S2382 eye phenotype. (Karim et al., 1996)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Complements	Taf1^EP421 (Wassarman et al., 2000)
Fails to complement	Taf1¹ (Wassarman et al., 2000) Taf1^EP421-EX1 (Wassarman et al., 2000) Taf1^S-625 (Wassarman et al., 2000) Taf1^XS-2232 (Wassarman et al., 2000)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Alleles of Taf1 form an allelic series based on phenotypic strength: Taf1^XS-2232/Taf1^EP421 > Taf1^S-136/Taf1^EP421 > Taf1^S-625/Taf1^EP421 > Taf1^EP421/Taf1^EP421. (Wassarman et al., 2000)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	SR3-5^S-136 (Wassarman et al., 2000, Karim et al., 1996, ) Taf1^S-136 Taf250^S-136
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Wassarman et al., 2000, Proc. Natl. Acad. Sci. U.S.A. 97(3): 1154--1159 TAF250 is required for multiple developmental events in Drosophila. [FBrf0125151] Karim et al., 1996, Genetics 143(1): 315--329 A screen for genes that function downstream of Ras1 during Drosophila eye development. [FBrf0087493]

Allele Dmel\Taf1S-136

Allele Dmel\Taf1^S-136