Allele Dmel\TfIIA-S^E32

General Information
Symbol	Dmel\TfIIA-S^E32	Species	D. melanogaster
Name		FlyBase ID	FBal0049209
Feature type	allele	Associated gene	Dmel\TfIIA-S

Allele class	amorphic allele - genetic evidence
Mutagen	Delta2-3
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class	amorphic allele - genetic evidence (Zeidler et al., 1996)
Mutagen	Delta2-3 (Zeidler et al., 1996)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	P{FZ}Pli^F125 (Zeidler et al., 1996)
Nature of the lesion	Statement Reference Deletion of TfIIA-S coding region. P{FZ}F125 may have locally reinserted into the 5' region of TfIIA-S and then subsequently imprecisely excised. (Zeidler et al., 1996)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| embryonic stage \| recessive (Zeidler et al., 1996)
Phenotype Manifest In

Detailed Description
	Statement Reference Embryos die at stage 15-16 of embryogenesis. Mutant embryos appear normal up until this stage. No clones of mutant cells are ever recovered in eye discs, adult eyes or cuticle indicating that the mutant is cell lethal and that the survival of embryos to stage 15-16 is due to maternal contribution. (Zeidler et al., 1996)
External Data
Linkouts
Interactions
Phenotypic Class
NOT Suppressor of
Statement Reference TfIIA-S^E32 is a non-suppressor of lethal phenotype of Ras85D^V12.sev, sev^{S11.T:Hsap\MYC} (Maixner et al., 1998)
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference The lethality caused by sev^{S11.T:Hsap\MYC} in combination with Ras85D^V12.sev is not suppressed by TfIIA-S^E32. (Maixner et al., 1998)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescued by	TfIIA-S^E32 is rescued by TfIIA-S^+t4 (Zeidler et al., 1996)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	TFIIA-S^E32 (Maixner et al., 1998) TfIIA-S^E32
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Maixner et al., 1998, Dev. Genet. 23(4): 347--361 A screen for mutations that prevent lethality caused by expression of activated Sevenless and Ras1 in the Drosophila embryo. [FBrf0105879] Zeidler et al., 1996, Genes Dev. 10(1): 50--59 Drosophila TFIIA-S is up-regulated and required during Ras-mediated photoreceptor determination. [FBrf0086204]

Allele Dmel\TfIIA-SE32

Allele Dmel\TfIIA-S^E32