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General Information
Symbol
Dmel\Tm1el4
Species
D. melanogaster
Name
FlyBase ID
FBal0049225
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

dendritic arborising neuron & dendrite (with Tm1S130510)

dorsal multidendritic neuron ddaE & dendrite

dorsal multidendritic neuron ddaE & dendrite (with Tm1S130510)

Detailed Description
Statement
Reference

The dendrites of dorsal cluster dendritic arborization (DA) neurons and ddaE neurons overextend in Tm1S130510/Tm1el4 transheterozygotes. This phenotype also occurs in Tm1el4 homozygotes. The amount and length of lateral branches that extend from the dorsal dendrites is greater in Tm1S130510/Tm1el4 transheterozygotes than in wild-type embryos.

Mosaic egg chambers are viable and produce the germ cell less phenotype of Tm1gs1 and develop into sterile adults (embryos exhibit abdominal defects).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

Tm1el4/Tm1S130510 has neuroanatomy defective phenotype, enhanceable by stan[+]/stan51

Other
Phenotype Manifest In
Enhanced by
Statement
Reference

Tm1el4/Tm1S130510 has dorsal multidendritic neuron ddaE & dendrite phenotype, enhanceable by stan[+]/stan51

Tm1el4/Tm1eg9, osk[+]/osk1 has embryonic abdominal segment phenotype, enhanceable by E(To)1010/E(To)10[+]

Tm1el4/Tm1eg9, osk[+]/osk1 has embryonic abdominal segment phenotype, enhanceable by E(To)1212/E(To)12[+]

Tm1el4/Tm1eg9, osk[+]/osk1 has embryonic abdominal segment phenotype, enhanceable by E(To)13[+]/E(To)1313

Tm1el4/Tm1eg9, osk[+]/osk1 has embryonic abdominal segment phenotype, enhanceable by E(To)11/E(To)1[+]

Tm1el4/Tm1eg9, osk[+]/osk1 has embryonic abdominal segment phenotype, enhanceable by E(To)4[+]/E(To)44

Tm1el4/Tm1eg9, osk[+]/osk1 has embryonic abdominal segment phenotype, enhanceable by E(To)55/E(To)5[+]

Tm1el4/Tm1eg9, osk[+]/osk1 has embryonic abdominal segment phenotype, enhanceable by E(To)66/E(To)6[+]

Tm1el4/Tm1eg9, osk[+]/osk1 has embryonic abdominal segment phenotype, enhanceable by E(To)8[+]/E(To)88

Tm1el4/Tm1eg9, osk[+]/osk1 has embryonic abdominal segment phenotype, enhanceable by E(To)9[+]/E(To)99

Tm1el4/Tm1eg9, osk[+]/osk1 has embryonic abdominal segment phenotype, enhanceable by Rab11ETo11/Rab11[+]

Tm1el4/Tm1eg9, osk[+]/osk1 has embryonic abdominal segment phenotype, enhanceable by Rab11[+]/Rab11ETo3

Tm1el4/Tm1eg9, osk[+]/osk1 has embryonic abdominal segment phenotype, enhanceable by magoETo2/mago[+]

Tm1el4/Tm1eg9, osk[+]/osk1 has embryonic abdominal segment phenotype, enhanceable by vasETo14/vas[+]

Other
Additional Comments
Genetic Interactions
Statement
Reference

Embryos that are Tm1S130510/Tm1el4 transheterozygotes in a stan51/+ background have an enhanced dendritic overextension phenotype in ddaE neurons.

66% of eggs derived from Tm1eg9 +/Tm1el4 osk1 females do not develop into viable larvae. In 44% of the dead eggs, embryogenesis does not commence, or is terminated before cuticle formation, while 56% of the dead eggs have a characteristic "posterior group" phenotype with missing abdominal segments.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Tm1el4
Name Synonyms
Secondary FlyBase IDs
    References (3)