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General Information
Symbol
Dmel\caup1
Species
D. melanogaster
Name
FlyBase ID
FBal0049382
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
iro1
Key Links
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Transposition deletion breakpoint maps to an intron between the first and second exons in the protein coding region of the caup transcription unit.

Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Heterozygotes have a very mild phenotype with some thoracic bristles occasionally being missing. Double heterozygotes with Df(4)M101-62f or Df(1)260-1 have a much stronger phenotype, with some bristles missing at a high frequency. Homozygotes lack all bristles on the lateral part of the notum, so that only a median stripe of bristles remains. The mesothorax is narrower than normal, and has no notopleural suture. The scutellum is smaller than normal, and the wings are raised. caup1/Df(3L)iro-2 flies are viable and have a phenotype similar to caup1 homozygotes. caup1/caup1 flies carrying schs.PR develop tufts of bristles in the lateral part of the notum (that is normally naked in caup1 homozygotes) after heat shock.

Only the median strip of hairs remains on the notum.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

ara1 caup1/Df(3L)iro-2 flies lack lateral macrochaetae and the most lateral of microchaetae of the notum. The humeral bristles are normal and have wild-type axonal projections in these flies although the humerus is not morphologically normal. Bristles of variable size are formed in the otherwise naked lateral region of the notum if the flies are also carrying acHw-49c, at a position corresponding to that of the posterior supraalar bristle. This bristle has a contralateral axon branch in about 70% of cases.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Isolated as a mutation that alters the pattern of bristles when doubly heterozygous with Df(4)M101-62f.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
References (9)