Type II neuroblasts are completely absent in the brains of late third larval instar dpn1/dpn7 larvae. The number of type I neuroblasts is close to that of wild type at 9-12 hours after larval hatching (ALH), but is reduced compared to wild type at 48 hours ALH, and does not reduce further from 48 hours to 96 hours ALH.
Mushroom body neuroblasts are progressively lost in dpn1/dpn7 mutants: at the late third instar larval stage nearly half of the mushroom body neuroblasts are missing, and by the start of pupariation, 90% of them are lost.
Homozygous mushroom body neuroblast clones generated immediately after larval hatching have mostly lost their neuroblasts by 1-2 days after pupariation, in contrast to wild-type control clones, which always contain a neuroblast at this stage.
Heterozygous larvae show a slight decrease in the number of type II neuroblasts in the brain compared to wild type.
The few Df(2R)dpn-2/dpn7 mutant escapers that are seen are uncoordinated and flightless. The total number of neuroblasts is reduced during the larval stages. Type II neuroblasts are never observed at late stages of larval development although one is occasionally seen in early larval brains.
dpn7 mutant clones generated in type II neuroblasts are smaller than control clones. In contrast, clones that originate in type I clones are similar in size to controls.
Strongly feminizes triploid intersexes. Degree of feminization of the foreleg is unusually high (35% of forelegs are entirely female). May be cell lethal in germ-line clones.